Tests a mindfulness program for pain in people with multiple sclerosis
Tests whether mindfulness training reduces pain in adults with multiple sclerosis.
Plain-language title generated from the registry record
Registry title: Effectiveness of a Mindfulness-Based Intervention for Pain Management in Patients With Multiple Sclerosis (MPIMS).
Key facts
- Where
- Seville, SpainSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 80 years old?
Source: NCT07741864, who can take part
Where in Spain
- Hopsital Universitario Virgen MacarenaSeville, SpainNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Hospital Universitario Virgen Macarena
- Trial code
- NCT07741864
- Record updated
- 3 August 2026
- Original description
The goal of this clinical trial is to evaluate whether a mindfulness-based intervention is effective for reducing pain in adults with multiple sclerosis. It will also assess whether this intervention improves other symptoms commonly associated with pain, such as fatigue, sleep disturbances, anxiety, depression, and quality of life.Read full original descriptionShow less
Effectiveness of a Mindfulness-Based Intervention for Pain Management in Patients With Multiple Sclerosis
The goal of this clinical trial is to evaluate whether a mindfulness-based intervention is effective for reducing pain in adults with multiple sclerosis. It will also assess whether this intervention improves other symptoms commonly associated with pain, such as fatigue, sleep disturbances, anxiety, depression, and quality of life.
The main questions it aims to answer are:
* Does a mindfulness-based intervention reduce pain intensity in people with multiple sclerosis? * Does the intervention improve fatigue, sleep quality, emotional well-being, quality of life? * Does the effectiveness of the intervention differ according to the type of pain experienced by participants? Researchers will compare a mindfulness-based intervention with an educational program to determine whether mindfulness provides additional benefits for pain management in people with multiple sclerosis.
Participants will:
* Be randomly assigned to either the mindfulness intervention group or the educational control group. * Complete assessments before the intervention, immediately after the intervention, and at 1-month and 3-month follow-up visits. * If assigned to the mindfulness group, attend eight weekly 2.5-hour group sessions plus one 6-hour retreat, either in person or online. * If assigned to the control group, attend two 2-hour educational sessions during the study period. * Complete questionnaires evaluating pain, fatigue, physical function, anxiety, depression, sleep quality, quality of life, and mindfulness throughout the study.
Inclusion: Adults aged 18 to 80 years; Diagnosis of multiple sclerosis with an Expanded Disability Status Scale (EDSS) score between 1.0 and 7.0; Presence of pain; Ability to provide written informed consent.
Exclusion: If receiving stable pain medication, treatment must have been maintained for at least 4 months before enrollment; Severe cognitive impairment; Diagnosed psychiatric disorders (e.g., schizophrenia or personality disorders); Participation in another non-pharmacological intervention specifically aimed at pain management; Unwillingness to provide informed consent.