AI video avatars to invite Veterans with heart disease into clinical trials
Tests AI-generated video avatars to engage Veterans with cardiovascular disease in trials.
Plain-language title generated from the registry record
Registry title: Empowering Veterans in Research Effectively Using Virtual Engagement Tools
Key facts
- Where
- Palo Alto, United StatesSee the site
Where in United States
- VA Palo Alto Health Care System, Palo Alto, CAPalo Alto, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- VA Office of Research and Development
- Trial code
- NCT07741955
- Record updated
- 3 September 2026
- Original description
Cardiovascular disease is the leading cause of death among Veterans. Clinical trials are essential for developing better treatments, but Veterans remain underrepresented in these studies due to barriers including limited health literacy, lack of awareness, and mistrust. Current outreach approaches rely on either in-person physician conversations, which are limited by workforce constraints, or mailed letter invitations, which often fail to engage Veterans with limited health literacy. This study tests whether AI-generated video avatars can improve Veteran engagement in cardiovascular clinical trials.Read full original descriptionShow less
EVERYVET (Empowering VEterans in Research effectivelY Using Virtual Engagement Tools): A Patient-Centered Study
Cardiovascular disease is the leading cause of death among Veterans. Clinical trials are essential for developing better treatments, but Veterans remain underrepresented in these studies due to barriers including limited health literacy, lack of awareness, and mistrust. Current outreach approaches rely on either in-person physician conversations, which are limited by workforce constraints, or mailed letter invitations, which often fail to engage Veterans with limited health literacy. This study tests whether AI-generated video avatars can improve Veteran engagement in cardiovascular clinical trials.
Inclusion: Veteran receiving a mailed invitation to participate in the parent VA Cooperative Studies cardiovascular trial (therefore meeting inclusion criteria of the parent VA Cooperative Studies trial); Veteran receiving care at VAPAHCS; Recently invited (within 3 months) to participate in an existing cardiovascular clinical trial at VAPAHCS; Able to provide informed consent in English; Veteran receiving care at VAPAHCS or a participating VA-CTC site; Able to view a brief video and complete a short survey in English; VA study coordinator or trial investigator actively engaged in cardiovascular clinical trial recruitment at VAPAHCS or a VA-CTC site; Willing to participate in a 60-90 minute virtual focus group.
Exclusion: Cognitive impairment documented in the electronic health record; Any exclusion criterion of the parent VA Cooperative Studies cardiovascular trial; Inability to communicate in English at a level sufficient for qualitative interview participation; Inability to communicate in English at a level sufficient for survey completion.