Studies weight gain in pregnancy after prior GLP-1 medicine use
Compares pregnancy weight gain and outcomes in women who used GLP-1 medicines before pregnancy.
Key facts
- Who runs it
- University of Kansas Medical Center
- Where
- Kansas City, United StatesSee the site
- Trial code
- Registry title
- Gestational Response, Outcomes, and Weight After GLP-1 Use
- Status
- Recruiting
- People taking part
- 400 people, planned
- Started
- 13 Apr 2026
- Expected to end
- Apr 2028
- Type of study
- Observational, 2 groups
- Record updated
- 4 August 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adult pregnant women, up to 20 weeks pregnant at the first visit. Some have used GLP-1RA weight-loss medicines before pregnancy and some have not.
- Age
- 18 Years to 45 Years
- Sex
- Women only
- Disease stage
- Pregnant, 20 weeks or less at the first visit.
- Earlier treatment
- One group has used a GLP-1RA medicine before. The other group has never used one.
Main reasons for not taking part
- Type 2 diabetes
- History of bariatric surgery
- Multiple gestation
- Cannot consent for themselves
- Cannot read and speak English
This trial only enrols pregnant participants. The registry sentence this rests on: Less than or equal to 20 weeks gestation at first visit
The registry criteria, word for word
Show all 10 criteriaShow less
Who can take part
- Adult women
- Less than or equal to 20 weeks gestation at first visit
- English speaking
Who cannot take part
- Type 2 diabetes
- History of bariatric surgery
- <18 years at time of initial visit
- Multiple gestation
- Cannot consent for themselves
- Cannot read and speak English
- Incarcerated
Check if you might fit
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 45 years old?
Where in United States
- University of Kansas Medical CenterKansas City, United StatesContact: Molly FainTaking people
About the trial
What the trial wants to find out
The goal of this observational study is to learn if using GLP-1RA medications for weight loss before pregnancy influences gestational weight gain and pregnancy outcomes. The main aims of the study are to:
Read full original descriptionShow less
* Compare gestational weight gain between women with preconception GLP-1RA exposure and those without exposure. * Compare obstetrical outcomes between women with preconception GLP-1RA exposure and those without exposure.
Researchers will compare pregnant women with a history of GLP-1RA use to pregnant women who have not used a GLP-1RA to compare differences.
Participants will be asked to complete questionnaires at multiple timepoints during and after pregnancy that ask questions about medication history, thoughts and feelings around food, etc.
The 2 groups in the trial
- GLP-1RA users
Participants with a history of GLP-1RA use.
- GLP-1RA nonusers
Participants who have never used a GLP-1RA medication.
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Gestational Response, Outcomes, and Weight After GLP-1 Use
- Plain-language title
- Studies weight gain in pregnancy after prior GLP-1 medicine useGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 13 November 2026.
- Fit questions
- Built from NCT07743567, who can take part
- Record updated
- 4 August 2026