PrOspEctive Metastases Imaging (POEM)
Key facts
- Where
- Wilrijk, BelgiumSee the site
Where in Belgium
- GZA St AugustinusWilrijk, BelgiumTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Cancer Research Antwerp
- Trial code
- NCT07781306
- Record updated
- 24 August 2026
- Original description
This is a non-interventional, observational study with an optional interventional biobanking activity. Liver metastases of patients undergoing partial hepatectomy will be sampled completely while respecting the orientation used for medical imaging, in order to correlate the histopathological growth patterns in a 3D-map with the imaging characteristics. The full pathological sampling will only use remnant tissue.Read full original descriptionShow less
Prospective Complete Histopathological Characterization of Liver Metastases From Colorectal and Breast Carcinoma to Predict the Histopathological Growth Patterns by Medical Imaging - PrOspEctive Metastases Imaging (POEM)
This is a non-interventional, observational study with an optional interventional biobanking activity. Liver metastases of patients undergoing partial hepatectomy will be sampled completely while respecting the orientation used for medical imaging, in order to correlate the histopathological growth patterns in a 3D-map with the imaging characteristics. The full pathological sampling will only use remnant tissue.
Inclusion: ≥ 18 years old; Patients with liver metastatic colorectal or breast carcinoma undergoing a surgical excision of the liver metastases; Therapy-naive patients as well as patients with neo-adjuvant therapy are eligible for inclusion; Willingness of the patient to participate in this study demonstrated by signed written informed consent.
Exclusion: Patients without MRI or CT of the liver prior to surgery; Prior radiofrequency ablation (RFA) or transarterial chemoembolization (TACE) on the liver metastasis that would be operated; Time interval between medical imaging, CT and/or MRI is more than 12 weeks (nb: time interval is preferably less than 4 weeks but this is not an exclusion criterium).