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Comparing two pulsed field ablation methods for atrial fibrillation

Compares two catheter ablation approaches in adults with atrial fibrillation likely to return.

Plain-language title generated from the registry record
Registry title: Single-Shot Versus Focal Dual-Energy Pulsed Field-Based Ablation for Atrial Fibrillation

Key facts

Where
Herne, GermanySee the site

Where in Germany

  • Marien Hospital HerneHerne, GermanyNo longer taking part

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Trial details

Who runs it
Marien Hospital Herne
Trial code
NCT07783919
Record updated
25 August 2026
Original description
Comparison of single-shot PFA systems with focal dual-energy (PFA/RF) in patients at high risk of atrial fibrillation recurrence.Read full original descriptionShow less

DUAL AF Single-Shot Versus Focal Dual-Energy Pulsed Field-Based Ablation for Atrial Fibrillation

Comparison of single-shot PFA systems with focal dual-energy (PFA/RF) in patients at high risk of atrial fibrillation recurrence.

Inclusion: Age ≥ 18 years; First-time pulmonary vein isolation; Symptomatic atrial fibrillation:; Paroxysmal atrial fibrillation (≥ 2 episodes in the last 6 months) and one of the following:; CHA2DS2VA score ≥ 2, ≥ 1 cardioversion in the last 6 months or Left atrial (LA) diameter ≥ 45 mm; o or persistent atrial fibrillation (≥ 1 episode in the last 6 months).

Exclusion: Severe mitral or tricuspid valve regurgitation requiring therapy; Previous left atrial endocardial or epicardial ablation; Atrial fibrillation due to reversible or non-cardiac causes; Pregnancy or breastfeeding; Lack of opportunity for reliable study participation.

ClinicalTrials.gov NCT07783919