Brain Signals During Thinking Tasks in People With Drug-Resistant Epilepsy
Records brain activity during thinking tasks in adults with drug-resistant epilepsy.
Plain-language title generated from the registry record
Registry title: Study of the Intracerebral Electrophysiological Signature in the Epileptic Patient
Key facts
- Where
- Toulouse, FranceSee the site
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 18 and 65 years old?
Source: NCT07796984, who can take part
Where in France
- Electrophysiologie cérébrale, épilepsie, sommeil, Hôpital Pierre Paul RiquetToulouse, FranceNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University Hospital, Toulouse
- Trial code
- NCT07796984
- Record updated
- 1 September 2026
- Original description
As part of the clinical management of certain severe, drug-resistant forms of epilepsy, it is necessary to implant electrodes in the brain to identify the epileptic network prior to potential neurosurgical resection of the source zones. This standardized procedure, known as Stereo-Electroencephalography (SEEG), was developed in France in the 1960s. The electrodes remain implanted for several days-typically two weeks-while awaiting spontaneous epileptic seizures. During this period, the patient remains hospitalized, and their electroencephalographic activity is recorded around the clock.Read full original descriptionShow less
Study of the Intracerebral Electrophysiological Signature of Cognitive Processes and Functional Mapping in Patients With Drug-resistant Epilepsy
As part of the clinical management of certain severe, drug-resistant forms of epilepsy, it is necessary to implant electrodes in the brain to identify the epileptic network prior to potential neurosurgical resection of the source zones. This standardized procedure, known as Stereo-Electroencephalography (SEEG), was developed in France in the 1960s. The electrodes remain implanted for several days-typically two weeks-while awaiting spontaneous epileptic seizures. During this period, the patient remains hospitalized, and their electroencephalographic activity is recorded around the clock.
Patients can be asked to perform cognitive tasks (such as tasks involving memory, attention, vision, language, and decision-making) while awake or asleep; the results can then be correlated with the intracerebral electroencephalographic activity recorded simultaneously as part of their clinical care. This approach makes it possible to capture the electrophysiological signatures of specific cognitive processes, thereby enabling researchers to: 1) create a brain map of electrophysiological signatures, 2) improve standard models of cognitive function, and 3) study the dysfunction of these processes in epilepsy.
Inclusion: Patient with drug-resistant focal epilepsy undergoing SEEG evaluation as part of the pre-surgical workup for epilepsy; Intellectual capacity sufficient to perform cognitive tasks, receive information about the study procedure, and understand the information sheet.
Exclusion: Patients already participating in another research project that prohibits participation in another study.