Testing a Food Carbohydrate Powder to Increase Fullness in Teens With Obesity
Tests a carbohydrate powder for feeling fuller in adolescents with obesity.
Plain-language title generated from the registry record
Registry title: Supplementation of Gut-brain Axis (GLP-1)-Activating Carbohydrates for Increasing Satiety in Adolescents With Obesity
Key facts
- Where
- Indianapolis, United StatesSee the site
- Phase
- Phase 2
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 12 and 18 years old?
Source: NCT07823452, who can take part
Where in United States
- Riley Hospital for Children at IU HealthIndianapolis, United StatesNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- Indiana University
- Trial code
- NCT07823452
- Record updated
- 21 October 2026
- Original description
Glucagon-like peptide (GLP1) drugs have quickly become a standard treatment for the adults with obesity. These drugs target the appetite control center of the brain, which clows the rate of stomach emptying, and makes a person feel full. The researchers are exploring this response in children. This study is being conducted to better understand how two food carbohydrates affect the appetite control center of the brain. The investigators want to see if a special carbohydrate powder that is mixed with 1 cup of water twice a day will appetite.Read full original descriptionShow less
Supplementation of Gut-brain Axis (GLP-1)-Activating Carbohydrates for Increasing Satiety in Adolescents With Obesity
Glucagon-like peptide (GLP1) drugs have quickly become a standard treatment for the adults with obesity. These drugs target the appetite control center of the brain, which clows the rate of stomach emptying, and makes a person feel full. The researchers are exploring this response in children. This study is being conducted to better understand how two food carbohydrates affect the appetite control center of the brain. The investigators want to see if a special carbohydrate powder that is mixed with 1 cup of water twice a day will appetite.
Inclusion: Children ages 12 to ≤18 years and older with obesity, a BMI ≥95% for age and sex; English-speaking subjects; Children who have been on stable dosing of medications for 3 months which secondarily lead to weight gain, weight loss, or appetite suppression; Children able to stay on a stable dose of all concomitant medications throughout the study treatment period.
Exclusion: Children with any intestinal resection; Children taking any medications or supplements for weight loss within 30 days prior to enrollment in the study; Children with malabsorptive disorders including inflammatory bowel disease, Celiac disease, and short bowel syndrome; Children with Type 1 or Type 2 Diabetes Mellitus; Subject has any condition that, in the opinion of the investigator, would compromise the well-being of the subject or would compromise the study or prevent the subject from meeting or performing study requirements; Females who are or planning to become pregnant or are breastfeeding.