Brain activity and thinking tasks in people with early psychosis
Studies thinking tasks and brain waves in people with early psychosis and healthy volunteers.
Plain-language title generated from the registry record
Registry title: State Representation in Early Psychosis 2
Key facts
- Where
- Minneapolis, United StatesSee the 2 sites
Could this be for you?
Answer for yourself. This is not a decision: only the study team can say whether you can take part.
- Are you between 15 and 45 years old?
Source: NCT07834203, who can take part
Where in United States
- University of Minnesota Ambulatory Research CenterMinneapolis, United StatesTaking people
- University of Minnesota Department of PsychologyMinneapolis, United StatesTaking people
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Trial details
- Who runs it
- University of Minnesota
- Trial code
- NCT07834203
- Record updated
- 22 September 2026
- Original description
This observational study will examine behavioral and electroencephalography measures related to state representation in individuals with early psychosis and healthy control participants.Read full original descriptionShow less
State Representation in Early Psychosis 2
This observational study will examine behavioral and electroencephalography measures related to state representation in individuals with early psychosis and healthy control participants.
Participants will complete clinical interviews, self-report measures, cognitive assessments, computerized behavioral tasks, and EEG assessments. The study will evaluate performance and computed parameters from the Translational Orientation Pattern Expectancy task and Translational Bandit Task, along with EEG variables related to cognitive control, reward processing, and neural synchrony.
The study aims to better understand heterogeneity in early psychosis and identify neurocognitive and neurophysiologic markers that may inform future precision psychiatry approaches.
Inclusion: All participants:; Aged between 15 and 45 years; English proficiency, as determined by staff observation and participant self-report; Estimated IQ at or above 70, as estimated by cognitive assessments; Estimated visual acuity at 20/40, as estimated by the visual acuity test; Early Psychosis participants:; Clinical diagnosis of schizophrenia, schizoaffective disorder, schizophreniform disorder, psychosis NOS, bipolar disorder with psychosis, or major depressive disorder with psychosis; Age 35 years or younger, or age 36 to 45 years with onset of psychotic symptoms within the previous 5 years; Achieved clinical stability, defined as outpatient status for at least one month prior to study participation.
Exclusion: Previous clinically significant head injury or prolonged unconsciousness, as determined by the investigators; Meets criteria for severe substance or alcohol use disorder within 3 months of behavioral assessment; Presence of any major medical condition that, in the opinion of the investigators, would impede participation or put the participant at additional risk; Presence of a major neurological disorder; Healthy Control participants:; Meets DSM-5 criteria for psychotic or bipolar disorder; Has a first-degree family history of psychotic or bipolar disorder; Presence of a major neurological disorder; All participants:; Unable or unwilling to provide informed consent; Unable to demonstrate adequate decisional capacity, in the judgment of the consenting study staff member; Illiterate; Has participated in significant formal cognitive training programs, as determined by the investigators; Meets criteria for clinical risk of suicidal behavior; Early Psychosis participants:.