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Beetroot juice and exercise effects on blood pressure in young adults with excess weight

Tests beetroot juice taken with exercise on blood pressure in young adults.

Plain-language title generated from the registry record
Registry title: Post-exercise Blood Pressure With Inorganic Nitrate

Key facts

Where
Charlottesville, United StatesSee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 40 years old?

Source: NCT07869472, who can take part

Where in United States

  • University of VirginiaCharlottesville, United StatesNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
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Trial details

Who runs it
University of Virginia
Trial code
NCT07869472
Record updated
9 October 2026
Original description
This study is examining whether acute inorganic nitrate supplementation in the form of beetroot juice, paired with an acute bout of exercise, affects blood pressure and what is the magnitude of the difference compared to exercise alone.Read full original descriptionShow less

Effects of Inorganic Nitrate Supplementation on Post-exercise Hypotension Response Following Acute Exercise in Young Adults With Elevated Body Mass Index and Blood Pressure

This study is examining whether acute inorganic nitrate supplementation in the form of beetroot juice, paired with an acute bout of exercise, affects blood pressure and what is the magnitude of the difference compared to exercise alone.

Inclusion: Willingness and ability to comply with scheduled visits and study procedures; Males and females, ages 18-40 years old; Sedentary (<150 minutes of moderate intensity aerobic exercise per week, or not engaged in a regular exercise program at all; Resting systolic BP ≥ 120 mmHg; BMI ≥ 30 kg/m2; Waist circumference ≥94 cm for males and ≥80 cm for females; Be able to perform exercise on a cycle ergometer without assistance; Stable medication regimen for the last 6 months; Be able to discontinue the use of inorganic nitrate rich foods such as beets, arugula, spinach, celery, and grapefruit throughout the duration of the study.

Exclusion: Has experienced significant weight loss ~3 kg in the last three months or taking any weight loss drugs; Currently on hormone replacement of any kind; Oral antibiotic use within previous four weeks including over-the-counter antibacterial mouthwash or a mouthwash containing chlorhexidine and unwilling to discontinue use; Current medical condition that prohibits exercising at high intensities; History of medical conditions that would prohibit high intensity exercise, such as:, uncontrolled hypertension (≥140/90), diabetes, myocardial infarction, cerebrovascular event, known cardiovascular, pulmonary, renal, metabolic diseases, and acute or unstable disease other than high BMI and waist circumference; Oral cancer/severe oral disease; Currently taking or have taken any of the following medications in the last 4 weeks (calcium channel blockers, statins, ACE or renin inhibitors, angiotensin receptor blockers, organic nitrates (e.g., nitroglycerine, alpha- or beta-blockers, diuretics, proton pump inhibitors, PDE-5 inhibitors (e.g., Cialis, Viagra), or xanthine oxidase inhibitors (e.g., Allopurinol)); Body mass index ≤ 29.9 Kg/m2; Smoker within last 5 years; Current injuries that would prohibit exercising on a stationary bike; Currently restricted by medical doctor to engage in exercise; Had hysterectomy or oophorectomy; Pregnant women or planning to be pregnant, Fetuses, neonates, children, prisoners, cognitively impaired, non-English speaking participants.

ClinicalTrials.gov NCT07869472