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Home blood pressure checks and self-adjusted medication for people with high blood pressure

Tests people adjusting their own blood pressure medication at home, guided by a doctor.

Plain-language title generated from the registry record
Registry title: Antihypertensive Self-titration in US Primary Care

Key facts

Where
Somerville, United StatesSee the site

Where in United States

  • Mass General BrighamSomerville, United StatesNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
Brigham and Women's Hospital
Trial code
NCT07869966
Record updated
13 October 2026
Original description
The objective of this study is to pilot test self-titration intervention procedures. We are testing a new way to manage high blood pressure from home. In this study, patients will check their blood pressure at home and take steps to adjust their blood pressure medications if needed, following a plan outlined with a primary care doctor. Participation in this study will last up to 6 months.Read full original descriptionShow less

Antihypertensive Self-titration in US Primary Care

The objective of this study is to pilot test self-titration intervention procedures. We are testing a new way to manage high blood pressure from home. In this study, patients will check their blood pressure at home and take steps to adjust their blood pressure medications if needed, following a plan outlined with a primary care doctor. Participation in this study will last up to 6 months.

Participation will include a research visit to review the blood pressure management process. A primary care provider will also develop a medication plan for each participant to follow during the study and address any questions at their upcoming visit. During the study, each participant will be asked to check their blood pressure at home every day for 1-2 weeks a month using a study-provided blood pressure cuff. They will be asked to follow a set of instructions to request a medication change from their provider, based on their blood pressure readings. Participation may also include lab visits and additional visits with a primary care physician before making medication changes, if needed. There will also be a follow-up visit within 6 months.

Inclusion: Age ≥35 years; Prescribed 1 or 2 antihypertensives; Average of last 3 BPs > 130/80 (home \& clinic); Upcoming scheduled PCP visit; Averaged BP >130/80 at nurse visit.

Exclusion: Dementia or significant cognitive impairment (nurse / PCP discretion); Unable to read English or Spanish; Unable to self-monitor (by nurse assessment); Pregnant or actively seeking to become pregnant; Terminal diagnosis or hospice; Family member already participating in the trial.

ClinicalTrials.gov NCT07869966