Not yet taking people in FranceNo phase
Follow-up of people after endoscopic removal of colon lesions
Follows adults whose colon growths were removed through an endoscope.
Key facts
- Who runs it
- University Hospital, Bordeaux
- Where
- Angers, Dijon, Limoges, Lyon, Nantes, Nîmes, Paris, Pessac, Rennes, Saint-Herblain, and Vandœuvre-lès-Nancy, FranceSee the 14 sites
- Trial code
- Registry title
- Follow-up After Oncological Resection by Endoscopic Colorectal ESD (Endoscopic Submucosal Dissection)
- Status
- Not yet recruiting
- People taking part
- 1,200 people, planned
- Started
- Oct 2026
- Expected to end
- Dec 2030
- Type of study
- Observational
- Treatments tested
- Surgery, Radiochimiotherapy
- Record updated
- 16 October 2026
Who can take part
AI summary
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who had a small, early colorectal cancer removed by endoscopic submucosal dissection and whose removed tissue showed a high risk of spread to the lymph nodes.
- Age
- 18 years or older
- Sex
- All sexes can join.
- Disease stage
- Early (superficial, T1) colorectal cancer removed by endoscopy. The removed tissue must show at least one high-risk sign: invasion depth of 1000 microns or more, tumor budding grade 2 or higher, or cancer cells in lymph or blood vessels.
- Earlier treatment
- Must have had submucosal dissection (endoscopic removal) and be included in the French FECCo registry since September 2019.
Main reasons for not taking part
- Crohn's disease or ulcerative colitis
- Familial adenomatous polyposis or a genetic risk of colorectal cancer
- Colon tumor of stage T2 or higher
- Not included in the FECCo registry
- Has objected after reading the information notice
The registry criteria, word for word
Show all 9 criteriaShow less
Who can take part
- Adult patient (18 years or older)
- Presumed diagnosis of localized superficial colorectal cancer (T1) during endoscopy using the Conecct classification, confirmed by subsequent histopathological analysis
- Patient included in the French Colorectal ESD Cohort in Experts Centers (FECCo registry) since September 2019 for submucosal dissection
- Histological analysis of the resection specimen revealing a superficial colorectal adenocarcinoma with high risk of lymphatic recurrence, defined by at least one of the following criteria: submucosal invasion depth ≥ 1000 microns, tumor budding grade ≥ 2, presence of lymphatic and/or vascular emboli
Who cannot take part
- History of Crohn's disease (ICD-10: K50) or ulcerative colitis (ICD-10: K51)
- History of familial adenomatous polyposis and/or genetic predisposition to colorectal cancer (ICD-10: D12.6+0/1/2/4/5 and 6)
- Malignant tumor of the colon staged ≥ T2
- Patients not included in the FECCo registry
- Documented objection through the non-opposition form following review of the information notice
Where in France
- Clinique de l'AnjouAngers, FranceContact: Edouard CHABRUN, MDNo longer taking part
- Chu Dijon BourgogneDijon, FranceContact: Thibault DEGAND, MDNo longer taking part
- CHU de LimogesLimoges, FranceContact: Jérémie JACQUES, PROFNo longer taking part
- Clinique Jean MermozLyon, FranceContact: Sarah LEBLANC, MDNo longer taking part
- Hospices Civils de Lyon - Hôpital Édouard HerriotLyon, FranceContact: Mathieu PIOCHE, PROFNo longer taking part
- Clinique Jules VerneNantes, FranceContact: Bertrand BRIEAU, MDNo longer taking part
- CHU NîmesNîmes, FranceContact: Ludovic CAILLO, MDNo longer taking part
- AP-HP Hôpital CochinParis, FranceContact: Arthur BELLE, MDNo longer taking part
- AP-HP Hopital Europeen Georges PompidouParis, FranceContact: Guillaume PERROD, MDNo longer taking part
- Paris - Saint JosephParis, FranceContact: Yann LE BALEUR, MDNo longer taking part
- CHU de BordeauxPessac, FranceContact: Arthur BERGER, MDNo longer taking part
- CHU de RennesRennes, FranceContact: Timothée WALLENHORST, MDNo longer taking part
- Clinique Santé AtlantiqueSaint-Herblain, FranceContact: Nicolas MUSQUER, MDNo longer taking part
- CHRU de NancyVandœuvre-lès-Nancy, FranceContact: Marion SCHAEFER, MDNo longer taking part
About the trial
What the trial wants to find out
Colorectal cancer is a common and leading cause of death. Pre-cancerous lesions, as well as some so-called superficial cancers, can be resected via endoscopy. The technique chosen in the case of extensive lesions or superficial cancer is submucosal dissection. This technique helps avoid surgery, which has a higher morbidity and mortality (especially due to the non-preservation of the organ).
The group in the trial
- Surgery, Radiochimiotherapy, Surveillance
Patients who underwent surgery, radiochimiotherapy or nothing.
Treatment: Surgery, Radiochimiotherapy
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorData and sources
- Registry record
- Listed on ClinicalTrials.gov.
- Official title
- Follow-up After Oncological Resection by Endoscopic Colorectal ESD
- Plain-language title
- Follow-up of people after endoscopic removal of colon lesionsGenerated from the registry record. The registry title is the official one.
- AI summary
- From the trial's eligibility criteria. Read by machine on 13 November 2026.
- Record updated
- 16 October 2026