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Self-Applied Acupressure for Pain in People With Sickle Cell Disease

Tests acupressure with a handheld device in adults with sickle cell disease.

Plain-language title generated from the registry record
Registry title: Self-administered Acupressure in Patients With Sickle Cell Disease

Key facts

Where
Cincinnati and Irvine, United StatesSee the 2 sites

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 18 and 80 years old?

Source: NCT07875777, who can take part

Where in United States

  • University of CincinnatiCincinnati, United StatesNo longer taking part
  • University of California, IrvineIrvine, United StatesNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
University of Cincinnati
Trial code
NCT07875777
Record updated
15 October 2026
Original description
The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupressure analgesia in patients with sickle cell disease (SCD).Read full original descriptionShow less

Acupressure in Patients With Sickle Cell Disease

The proposed research is to determine the clinical efficacy and neurobiological mechanisms of acupressure analgesia in patients with sickle cell disease (SCD).

Inclusion: Any gender; 18-80 (Adults) years old; Have been diagnosed with SCD and experiencing chronic pain in the past 6 months; Either outpatient or inpatient or status changing between each other; Willing to limit the current and the introduction of any new medications or treatment modalities for control of pain symptoms during the study visits; Willing to stick to the scheduled acupressure treatments every other day for 5 weeks; Fluent in English and capable of giving written informed consent.

Exclusion: Presence of a concurrent autoimmune or inflammatory disease such as rheumatoid arthritis, systemic lupus erythematosus, inflammatory bowel disease, etc. that causes pain or any other chronic pain condition with pain greater than sickle pain; Diseases/conditions history includes but not limited to:; Head injury with substantial loss of consciousness Known non-SCD-related severe psychiatric illnesses (e.g. current schizophrenia, major depression with suicidal ideation) Significant visual, motor, or auditory impairment that would interfere with ability to perform study visits-related activities; Recent/ongoing alternative pain management with acupuncture/acupressure or acupuncture/acupressure-related techniques within the last 6 months.

ClinicalTrials.gov NCT07875777