Checking how consistent portal vein pressure readings are using an endoscopic ultrasound method
Compares repeated portal pressure measurements by endoscopic ultrasound in adults with liver disease.
Plain-language title generated from the registry record
Registry title: Within-Session Repeatability of EUS-Guided Portal Pressure Gradient Measurement
Key facts
- Where
- Rome, ItalySee the site
AI summary: who the study is looking for
From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.
The trial is looking for adults who already need an endoscopic ultrasound-guided portal pressure measurement. Each person has the measurement done twice in one session.
- Age
- 18 years or older
- Sex
- All sexes can join.
Main reasons for not taking part
- Cannot safely have endoscopy, sedation or ultrasound-guided vessel puncture
- Blood clotting problem that cannot be corrected
- Unstable circulation during the procedure
- Pregnant or breastfeeding
- Cannot give informed consent
Read by machine on 13 November 2026.
Where in Italy
- Fondazione Policlinico Universitario Agostino Gemelli IRCCSRome, ItalyContact: Francesco Santoapolo, MDNo longer taking part
Questions to ask the study team
- How often do I need to come in, and for how long each time?
- Are travel costs paid?
- Can I keep my own doctor?
- What happens if I want to stop?
Contact the study team: see the registry record → Contacts and Locations
Print a page for my doctorTrial details
- Who runs it
- University Hospital Muenster
- Trial code
- NCT07877298
- Record updated
- 26 October 2026
- Original description
This prospective multicentre observational reliability study will determine how much a repeated endoscopic ultrasound-guided portal pressure gradient (EUS-PPG) measurement differs from the first measurement in the same patient during the same procedural session. Each participant will undergo two complete EUS-PPG measurement sets using an identical 22-gauge measurement setup. The study will quantify within-session repeatability when the same expert performs both sets and inter-operator reproducibility when different operators perform the sets.Read full original descriptionShow less
Within-Session Repeatability and Inter-Operator Reproducibility of EUS-Guided Portal Pressure Gradient Measurement: A Prospective Multicentre Study
This prospective multicentre observational reliability study will determine how much a repeated endoscopic ultrasound-guided portal pressure gradient (EUS-PPG) measurement differs from the first measurement in the same patient during the same procedural session. Each participant will undergo two complete EUS-PPG measurement sets using an identical 22-gauge measurement setup. The study will quantify within-session repeatability when the same expert performs both sets and inter-operator reproducibility when different operators perform the sets.
Inclusion: Age 18 years or older; Clinical indication for EUS-guided portal pressure gradient measurement established independently of the study; Written informed consent, including consent for the additional measurement set.
Exclusion: Non-correctable coagulation disorder; Contraindication to endoscopy, sedation, or endosonography-guided vascular puncture; Hemodynamic instability at the time of the procedure; Any intervention between the two measurement sets that may alter portal pressure, including fluid administration beyond maintenance requirements, vasoactive substances, paracentesis, or variceal band ligation; Technically non-evaluable first measurement set; Pregnancy or breastfeeding; Inability to provide informed consent.