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Monitoring the right side of the heart in people on lung life support

Checks heart scans and blood tests in adults on ECMO for severe lung failure.

Key facts

Who runs it
Papworth Hospital NHS Foundation Trust
Where
Cambridge, United KingdomSee the site
Trial code
Registry title
Right Heart Injury Monitoring on ECMO
Status
Not yet recruiting
People taking part
30 people, planned
Started
Nov 2026
Expected to end
Jan 2028
Type of study
Observational
Treatments tested
  • Transthoracic echocardiogram
  • High sensitivity troponin
  • N-terminal pro-B-type natriuretic peptide
Record updated
19 October 2026

Who can take part

AI summary

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with severe acute respiratory failure who started VV-ECMO (a machine that does the work of the lungs) less than 72 hours ago. It tests twice-weekly heart scans and blood tests to watch the right side of the heart.

Age
18 years or older
Sex
All sexes
Disease stage
Severe acute respiratory failure, started on VV-ECMO less than 72 hours ago, either brought from another hospital or already an inpatient at RPH
Earlier treatment
Must have been put on VV-ECMO less than 72 hours ago because of severe acute respiratory failure

Main reasons for not taking part

  • Under 18 years old
  • Already taken part in this study
  • VV-ECMO after pulmonary thrombo-endarterectomy, as a bridge to lung transplantation, or after lung transplantation
  • VV-ECMO for any reason other than severe acute respiratory failure
  • Patient or personal consultee not fluent in English

The registry criteria, word for word

Show all 7 criteriaShow less

Who can take part

  • Adults (≥18 years old)
  • Less than 72 hours after being established on VV-ECMO due to SARF (either retrieved to RPH from another hospital or already an inpatient at RPH)

Who cannot take part

  • Patients that had been previously included in this study
  • Patients requiring VV-ECMO support post pulmonary thrombo-endarterectomy, as a bridge to lung transplantation or post lung-transplantation
  • Patients <18 years old
  • Any other reason for VV-ECMO support that is not SARF
  • Patients and/or Personal Consultee not fluent in English

Where in United Kingdom

  • Royal Papworth Hospital NHS Foundation TrustCambridge, United KingdomContact: Ana Francisca CaetanoNot yet recruiting

About the trial

What the trial wants to find out

This study aims to find out whether it is practical to introduce a consistent monitoring approach to the right side of the heart in patients supported with VV-ECMO.

Read full original descriptionShow less

VV-ECMO is a life support machine that takes over the work of the lungs to give them time to recover. It is used when lung injury is life-threatening.

Whilst receiving VV-ECMO support, in addition to the current standard of care, the following will be performed twice weekly:

* Heart scan (echocardiogram) * Blood tests (hs-troponin and NT-proBNP)

The patient's involvement in the study lasts for as long as they are on the life support machine, plus one final heart scan 48 hours after it is removed.

The group in the trial

  • SARF

    Patients supported with VV-ECMO due to severe acute respiratory failure.

    Treatment: Transthoracic echocardiogram, High sensitivity troponin, and N-terminal pro-B-type natriuretic peptide

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Data and sources

Registry record
Listed on ClinicalTrials.gov.
Official title
Feasibility Study for Monitoring Right Ventricular Injury in Patients With Severe Acute Respiratory Failure Supported With Veno-venous Extracorporeal Membrane Oxygenation
Plain-language title
Monitoring the right side of the heart in people on lung life supportGenerated from the registry record. The registry title is the official one.
AI summary
From the trial's eligibility criteria. Read by machine on 13 November 2026.
Record updated
19 October 2026