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Blood Pressure Targets in Preeclampsia Before 34 Weeks of Pregnancy

Compares tight and relaxed blood pressure goals in pregnant women with severe preeclampsia.

Plain-language title generated from the registry record
Registry title: Blood Pressure Goal in Preterm Preeclampsia

Key facts

Where
Columbus, United StatesSee the site

Where in United States

  • Ohio State University Wexner Medical CenterColumbus, United StatesNo longer taking part

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Trial details

Who runs it
Ohio State University
Trial code
NCT07894705
Record updated
26 October 2026
Original description
The purpose of this study is to compare latency (prolongation of pregnancy from diagnosis till delivery) in patients with hypertensive disorders of pregnancy (HDP) with severe features < 34 weeks gestational age (GA), undergoing expectant management between tight and permissive blood pressure (BP) groups.Read full original descriptionShow less

Blood Pressure Goal in Preterm Preeclampsia (BLiPP)

The purpose of this study is to compare latency (prolongation of pregnancy from diagnosis till delivery) in patients with hypertensive disorders of pregnancy (HDP) with severe features < 34 weeks gestational age (GA), undergoing expectant management between tight and permissive blood pressure (BP) groups.

Inclusion: Pregnant individuals; Age ≥ 18 years old; HDP with severe features; Planned inpatient admission for expectant management until delivery; GA 24 - ≤ 32 weeks GA; Singleton, non-anomalous fetus; Anticipated delivery at the study institution.

Exclusion: Poorly controlled preexisting chronic hypertension on ≥2 oral antihypertensive medications; Preexisting CKD with serum creatinine > 1.0; HDP with severe features > 32 weeks gestation at the time of admission; Contraindications to expectant management of preeclampsia with severe features per ACOG (attached); Severe FGR (EFW < 3rd percentile) or FGR with umbilical artery doppler abnormalities (absent or reversed end diastolic flow) at the time of enrollment; Multiple gestation; Major fetal anomaly (attached); PPROM/active preterm labor.

ClinicalTrials.gov NCT07894705