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Looking back at 25 years of advanced radiation treatment for tumors and other conditions

Reviews past advanced radiotherapy results and side effects in people treated at one hospital.

Plain-language title generated from the registry record
Registry title: Twenty-five Years of Advanced RadioTherapy at San Raffaele Hospital

Key facts

Where
Milan, ItalySee the site

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 6 and 90 years old?

Source: NCT07894900, who can take part

Where in Italy

  • Department of Radiation Oncology, IRCCS San Raffaele Scientific InstituteMilan, ItalyNo longer taking part

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?
Print a page for my doctor

Trial details

Who runs it
IRCCS San Raffaele
Trial code
NCT07894900
Record updated
29 October 2026
Original description
This retrospective observational study aims to evaluate the efficacy and toxicity of advanced radiotherapy (ART) techniques, including intensity-modulated radiotherapy (IMRT), image-guided radiotherapy (IGRT), and stereotactic radiotherapy (SRT), used at IRCCS Ospedale San Raffaele over the past 25 years and 5 months. The study includes treatments delivered using conventional fractionation, moderate hypofractionation, and ultra-hypofractionation. The primary endpoint is local control, defined as biochemical control in patients with prostate cancer.Read full original descriptionShow less

"Twenty-five Years of Advanced RadioTherapy (ART), With Intensity Modulation, Image-guidance, and Stereotactic Radiotherapy, With Classic Fractionation, Moderate- or Ultra-hypofractionation at San Raffaele Hospital "

This retrospective observational study aims to evaluate the efficacy and toxicity of advanced radiotherapy (ART) techniques, including intensity-modulated radiotherapy (IMRT), image-guided radiotherapy (IGRT), and stereotactic radiotherapy (SRT), used at IRCCS Ospedale San Raffaele over the past 25 years and 5 months. The study includes treatments delivered using conventional fractionation, moderate hypofractionation, and ultra-hypofractionation. The primary endpoint is local control, defined as biochemical control in patients with prostate cancer.

Inclusion: Patients with cancer; Patients with benign tumors/conditions; Treated with advanced radiotherapy techniques (IMRT, IGRT, SBRT, including Gamma Knife, CyberKnife, Tomotherapy, VMAT machines); Treated between January 2001 and May 2026.

Exclusion: Treated with 2D or 3D conformational radiotherapy,; Treated with palliative radiotherapy, not including an advanced radiotherapy technique; Patients with cancer; Treated before January 2001 or after May 2026.

ClinicalTrials.gov NCT07894900