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Results of knife-assisted full-thickness removal of rectal growths in colorectal cancer

Reviews past outcomes of knife-assisted rectal growth removal in adults.

Plain-language title generated from the registry record
Registry title: Outcomes of Knife-Assisted Full-Thickness Resection for Rectal Lesions: A Multicenter Study

Key facts

Where
Ghent, BelgiumSee the site

Where in Belgium

  • University Hospital GhentGhent, BelgiumTaking people

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Trial details

Who runs it
University Hospital, Ghent
Trial code
NCT07923682
Record updated
6 November 2026
Original description
This study looks at the results of a new technique called knife-assisted full-thickness resection (kFTR) for removing rectal lesions. In kFTR, a doctor uses an electrical knife to remove a rectal growth along with the full thickness of the rectal wall. Current methods for removing early rectal tumors each have limits depending on the size and location of the growth. This study collects data from hospitals in multiple countries to find out how well kFTR works and how safe it is. Researchers review medical records and endoscopy reports from patients who already had kFTR at participating hospitals. The main measures are whether the procedure was completed successfully, whether the growth was removed in one piece, whether the edges were cancer-free, and how often complications occurred. The study also tracks hospital stay length, need for additional surgery, cancer recurrence, and death.Read full original descriptionShow less

Outcomes of Endoscopic Knife-Assisted Full-Thickness Resection for Rectal Lesions: An International Multicentre Retrospective Cohort Study

This study looks at the results of a new technique called knife-assisted full-thickness resection (kFTR) for removing rectal lesions. In kFTR, a doctor uses an electrical knife to remove a rectal growth along with the full thickness of the rectal wall. Current methods for removing early rectal tumors each have limits depending on the size and location of the growth. This study collects data from hospitals in multiple countries to find out how well kFTR works and how safe it is. Researchers review medical records and endoscopy reports from patients who already had kFTR at participating hospitals. The main measures are whether the procedure was completed successfully, whether the growth was removed in one piece, whether the edges were cancer-free, and how often complications occurred. The study also tracks hospital stay length, need for additional surgery, cancer recurrence, and death.

Inclusion: Patients aged 18 years and older; Knife-assisted full-thickness resection (kFTR) performed for a rectal lesion at a participating center.

Exclusion: Unavailable information regarding kFTR technical outcomes.

ClinicalTrials.gov NCT07923682