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Walking with restricted blood flow and immune cells in type 2 diabetes

Tests blood flow restriction walking and immunity in type 2 diabetes.

Plain-language title generated from the registry record
Registry title: Acute Blood Flow Restriction Walking on Immune Cell Phenotype and Function

Key facts

Where
Kelowna, CanadaSee the site

AI summary: who the study is looking for

From the trial's eligibility criteria. Machine-read from the registry text on this page, so it can be wrong. The registry text below and the trial team decide who can take part.

The trial is looking for adults with type 2 diabetes who do little exercise. It studies how walking on a treadmill with blood flow restriction affects immune cells.

Age
19 to 64 years
Sex
All sexes can join.
Disease stage
Type 2 diabetes with a current HbA1c of 5.7-9.0% (39–75 mmol/mol).
Earlier treatment
Diabetes medication must have been stable for the last 3 months.
Biomarker or test result
HbA1c of 5.7-9.0% (39–75 mmol/mol).

Main reasons for not taking part

  • Chronic muscle or joint condition, or a heart or blood vessel event within the last 2 years, that prevents exercise
  • Peripheral vascular disease or other reasons that rule out blood flow restriction
  • Low iron, anemia, or treatment for these
  • Any condition that changes red blood cells, such as sickle cell anemia
  • Heart disease, or a medicine that stops a heart rate monitor from tracking effort accurately

Read by machine on 11 November 2026.

Could this be for you?

Answer for yourself. This is not a decision: only the study team can say whether you can take part.

  • Are you between 19 and 64 years old?

Source: NCT07928531, who can take part

Where in Canada

  • University of British Columbia OkanaganKelowna, CanadaTaking people

Questions to ask the study team

  1. How often do I need to come in, and for how long each time?
  2. Are travel costs paid?
  3. Can I keep my own doctor?
  4. What happens if I want to stop?

Contact the study team: see the registry record → Contacts and Locations

Print a page for my doctor

Trial details

Who runs it
University of British Columbia
Trial code
NCT07928531
Record updated
10 November 2026
Original description
To conduct a randomized control trial to determine the impact of acute blood flow restriction treadmill walking on immune cell counts, function, and phenotype in adults living with type 2 diabetes.Read full original descriptionShow less

Impact of Acute Blood Flow Restriction Walking on Immune Cell Phenotype and Function in Adults withT2D

To conduct a randomized control trial to determine the impact of acute blood flow restriction treadmill walking on immune cell counts, function, and phenotype in adults living with type 2 diabetes.

Inclusion: Aged 19-64 years; Diagnosed with type 2 diabetes with current HbA1c 5.7-9.0%; Completing <150 minutes of moderate-vigorous physical activity per week.

Exclusion: Chronic musculoskeletal condition or recent (within 2 years) cardiovascular event preventing participation in exercise; Unstable type 2 diabetes medication of the last 3 months; Absolute contraindications to BFR (i.e., peripheral vascular disease); A self-reported diagnosis of low iron concentrations, anemia, or being treated for these conditions; A diagnosis of any red blood cell-altering condition (i.e., sickle cell anemia, poikilocytosis); Currently living with any cardiovascular disease, which would impact the ability to participate in exercise safely; Currently prescribed any medication which would impact the ability to use a heart rate monitor to accurately track intensity.

ClinicalTrials.gov NCT07928531