Acute lymphoblastic leukaemia trials in Australia

In Australia 23 Also abroad 564

23 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Where
Brisbane, Melbourne, Randwick
Age
6 months to 25 years
People
90 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06395103 · EU 2023-507178-41-00
Phase 2Taking people
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
Where
Hunter Regional Mail Centre, Parkville, Perth, South Brisbane
Age
366 days to 46 years
People
222 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06124157
Phase 1/2Taking people
Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression
Where
Fitzroy, Perth
Age
16 years and over
People
85 worldwide
Run by
AstraZeneca
See details and how to joinNCT07155226 · EU 2025-521299-76-00
Phase 3Taking people
Interfant-21 Treatment Protocol for Infants Under 1 Year With KMT2A-rearranged ALL or Mixed Phenotype Acute Leukemia
Where
Adelaide, Clayton, New Lambton Heights, Parkville, Perth, South Brisbane, Sydney, Westmead
Age
1 day to 1 year
People
160 worldwide
Run by
Princess Maxima Center for Pediatric Oncology
See details and how to joinNCT05327894 · EU 2022-502503-30-00
Phase 1/2Taking people
Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia
Where
Melbourne
Age
12 years and over
People
83 worldwide
Run by
AstraZeneca
See details and how to joinNCT07109219 · EU 2025-522372-93-00
Phase 1/2Taking people
Safety and Efficacy of Asciminib in Pediatrics and Young Adults With Relapse/Refractory (r/r) Philadelphia Positive (Ph+) or ABL-class Ph-like Acute Lymphoblastic Leukemia (ALL)
Where
Sydney
Age
1 year to 30 years
People
50 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07387926
Phase 1/2Taking people
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
Where
Melbourne
Age
12 years and over
People
255 worldwide
Run by
AstraZeneca
See details and how to joinNCT06137118 · EU 2023-505840-20-00
Phase 1/2Taking people
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
Where
Melbourne, Nedlands, Parkville, Saint Leonards
Age
30 days and over
People
447 worldwide
Run by
Syndax Pharmaceuticals
See details and how to joinNCT04065399 · EU 2024-513759-34-00
Phase 2Taking people
A Phase 2 Study of WU-CART-007, an Anti-CD7 Allogeneic CAR-T Cell Therapy in T-Cell Acute Lymphoblastic Leukemia and Lymphoblastic Lymphoma (T-RRex)
Where
Melbourne
Age
6 months and over
People
125 worldwide
Run by
Allotera Therapeutics
See details and how to joinNCT06514794
Phase 1Taking people
Dose-escalation and Dose-expansion Study of Safety of Azer-cel (PBCAR0191) in Participants With Relapsed/Refractory (r/r) Non-Hodgkin Lymphoma (NHL) and r/r B-cell Acute Lymphoblastic Leukemia (B-ALL)
Where
Adelaide, Camperdown, Fitzroy, Geelong, Liverpool
Age
18 years and over
People
135 worldwide
Run by
Imugene Limited
See details and how to joinNCT03666000
Phase 2/3Taking people
Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
Where
Melbourne, Perth, Randwick, South Brisbane, Sydney
Age
1 month to 18 years
People
1,800 worldwide
Run by
St. Anna Kinderkrebsforschung
See details and how to joinNCT01949129 · EU 2024-512657-24-00
Phase 2Taking people
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Where
Hunter Regional Mail Centre, Perth, Randwick, South Brisbane, Westmead
Age
1 year to 30 years
People
461 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT04546399
Phase 3Taking people
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
Where
Clayton, Hunter Regional Mail Centre, North Adelaide, Parkville, Perth, Saint Hobart, South Brisbane, Westmead
Age
365 days to 25 years
People
5,951 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT03959085
Phase 1/2Taking people
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
Where
Parkville, Perth, South Brisbane, Westmead
Age
Up to 22 years
People
960 worldwide
Run by
PedAL BCU, LLC
See details and how to joinNCT04726241
Phase 1/2Taking people
A Study of CTD402 in T-ALL/LBL Patients
Where
Sydney
Age
1 year and over
People
118 worldwide
Run by
Imviva Bio
See details and how to joinNCT07070219
No phaseTaking people
Physical Activity and Exercise During Early Treatment Phases for Childhood Acute Lymphoblastic Leukaemia to Protect Against Muscle Loss and Improve Frailty Outcomes
Where
Melbourne
Age
5 years to 17 years
People
60
Run by
Murdoch Childrens Research Institute
See details and how to joinNCT07325305
No phaseTaking people
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
Where
Perth
People
420 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT01790152
Phase 3Taking people
A Study of Olverembatinib in Patients With Newly Diagnosed Ph+ ALL (POLARIS-1)
Where
Adelaide, Melbourne, Perth, St Leonards
Age
18 years and over
People
350 worldwide
Run by
Ascentage Pharma Group Inc.
See details and how to joinNCT06051409 · EU 2024-511496-14-00
Phase 2Taking people
International Study for Treatment of High Risk Childhood Relapsed ALL 2010
Where
Clayton
Age
Up to 17 years
People
250 worldwide
Run by
Charite University, Berlin, Germany
See details and how to joinNCT03590171 · EU 2024-513070-21-00
No phaseTaking people
Current Practice of Ventilation Strategies in Children Undergoing General Anesthesia
Where
Perth
Age
Up to 16 years
People
10,000 worldwide
Run by
Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA)
See details and how to joinNCT06166706
Phase 3Taking people
Treatment Protocol for Children and Adolescents With Acute Lymphoblastic Leukemia - AIEOP-BFM ALL 2017
Where
Sydney, Westmead
Age
Up to 17 years
People
5,000 worldwide
Run by
Martin Schrappe
See details and how to joinNCT03643276 · EU 2023-509856-32-00
Phase 1Taking people
Tagraxofusp in Pediatric Patients With Relapsed or Refractory CD123 Expressing Hematologic Malignancies
Where
Sydney, Westmead
Age
1 year to 21 years
People
54 worldwide
Run by
Therapeutic Advances in Childhood Leukemia Consortium
See details and how to joinNCT05476770
No phaseEnrolling by invitation
A Long-Term Safety Follow-Up Study for Patients Treat With WU-CART-007
Where
Melbourne
Age
12 years and over
People
44 worldwide
Run by
Allotera Therapeutics
See details and how to joinNCT05509855