Acute lymphoblastic leukaemia: open trials in Canada

30 open trials have a site in Canada. Registry data; only the trial team decides who can take part.

NCT03150693
Inotuzumab Ozogamicin and Frontline Chemotherapy in Treating Young Adults With Newly Diagnosed B Acute Lymphoblastic Leukemia
Trial Treatment · Phase 3 · Alliance for Clinical Trials in Oncology
Arthur J.E. Child Comprehensive Cancer Centre, Calgary · QEII Health Sciences Centre/Nova Scotia Health Authority, Halifax · Jewish General Hospital, Montreal · Ottawa Hospital and Cancer Center-General Campus, Ottawa · CancerCare Manitoba, Winnipeg
Registry updated 2026-11-03
NCT06395103
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Trial Treatment · Phase 1/2 · Merck Sharp & Dohme LLC
Alberta Children's Hospital ( Site 1227), Calgary · McGill University Health Centre-Pediatric HematologyOncology ( Site 1223), Montreal · The Hospital for Sick Children ( Site 1225), Toronto
Registry updated 2026-10-30
NCT07570173
A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)
Trial Treatment · Phase 2/3 · Merck Sharp & Dohme LLC
Princess Margaret Cancer Center ( Site 0102), Toronto
Registry updated 2026-10-30
NCT06124157
A Study Testing the Combination of Dasatinib or Imatinib to Chemotherapy Treatment With Blinatumomab for Children, Adolescents, and Young Adults With Philadelphia Chromosome Positive (Ph+) or ABL-Class Philadelphia Chromosome-Like (Ph-Like) B-cell Acute Lymphoblastic Leukemia (B-ALL)
Trial Treatment · Phase 2 · National Cancer Institute (NCI)
Alberta Children's Hospital, Calgary · University of Alberta Hospital, Edmonton · IWK Health Centre, Halifax · McMaster Children's Hospital at Hamilton Health Sciences, Hamilton · The Montreal Children's Hospital of the MUHC, Montreal · Centre Hospitalier Universitaire Sainte-Justine, Montreal · CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Québec · Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke · Hospital for Sick Children, Toronto · British Columbia Children's Hospital, Vancouver · CancerCare Manitoba, Winnipeg
Registry updated 2026-10-27
NCT07155226
Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression
Trial Treatment · Phase 1/2 · AstraZeneca
Montreal · Toronto
Registry updated 2026-10-23
NCT07109219
Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia
Trial Treatment · Phase 1/2 · AstraZeneca
Toronto · Vancouver
Registry updated 2026-10-15
NCT06208735
CLIC-2201 for the Treatment of Relapsed/Refractory B Cell Malignancies
Trial Treatment · Phase 1 · British Columbia Cancer Agency
Alberta Children's Hospital, Calgary · Arthur J.E. Child Comprehensive Cancer Centre, Calgary · The Ottawa Hospital - General Campus, Ottawa · Princess Margaret Cancer Centre, Toronto · The Hospital for Sick Children, Toronto · BC Children ' s Hospital, Vancouver · Vancouver General Hospital, Vancouver
Registry updated 2026-10-14
NCT07648264
Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies
Trial Treatment · Phase 3 · CSL Behring
Horizon Health Network, Fredericton · McGill University Health Research Institute, Montreal
Registry updated 2026-10-14
NCT06137118
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
Trial Treatment · Phase 1/2 · AstraZeneca
Montreal · Toronto
Registry updated 2026-10-13
NCT04065399
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
Trial Treatment · Phase 1/2 · Syndax Pharmaceuticals
University Health Network, Toronto · The Hospital for Sick Children, Toronto
Registry updated 2026-10-09
NCT04094311
Study of Out of Specification for Tisagenlecleucel
Trial Treatment · Phase 3 · Novartis Pharmaceuticals
Hamilton · Montreal · Ottawa · Québec · Toronto
Registry updated 2026-09-15
NCT01949129
Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
Trial Treatment · Phase 2/3 · St. Anna Kinderkrebsforschung
Alberta Children's Hospital Division of Pediatric Oncology, Calgary · Montreal Children's Hospital, Montral · CHU Sainte-Justine Hematology-Oncology Division, Montreal · Hospital for Sick Children University of Toronto Division of Haematology/Oncology, Toronto · BC Children ' s Hospital, Vancouver · CancerCare Manitoba/University of Manitoba, Winnipeg
Registry updated 2026-09-04
NCT04546399
A Study to Compare Blinatumomab Alone to Blinatumomab With Nivolumab in Patients Diagnosed With First Relapse B-Cell Acute Lymphoblastic Leukemia (B-ALL)
Trial Treatment · Phase 2 · National Cancer Institute (NCI)
Alberta Children's Hospital, Calgary · University of Alberta Hospital, Edmonton · IWK Health Centre, Halifax · The Montreal Children's Hospital of the MUHC, Montreal · Centre Hospitalier Universitaire Sainte-Justine, Montreal · CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Québec · Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke · Janeway Child Health Centre, St. John's · British Columbia Children's Hospital, Vancouver · CancerCare Manitoba, Winnipeg
Registry updated 2026-09-01
NCT03959085
Inotuzumab Ozogamicin and Post-Induction Chemotherapy in Treating Patients With High-Risk B-ALL, Mixed Phenotype Acute Leukemia, and B-LLy
Trial Treatment · Phase 3 · Children's Oncology Group
Alberta Children's Hospital, Calgary · University of Alberta Hospital, Edmonton · IWK Health Centre, Halifax · McMaster Children's Hospital at Hamilton Health Sciences, Hamilton · Kingston Health Sciences Centre, Kingston · Children's Hospital, London · The Montreal Children's Hospital of the MUHC, Montreal · Children'S Hospital Of Eastern Ontario, Ottawa · CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Québec · Saskatoon Cancer Centre, Saskatoon · Jim Pattison Children's Hospital, Saskatoon · Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke · Janeway Child Health Centre, St. John's · Hospital for Sick Children, Toronto · British Columbia Children's Hospital, Vancouver · CancerCare Manitoba, Winnipeg
Registry updated 2026-08-25
NCT04726241
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
Trial Treatment · Phase 1/2 · PedAL BCU, LLC
Alberta Children's Hospital, Calgary · University of Alberta Hospital, Edmonton · IWK Health Centre, Halifax · Children's Hospital, London · The Montreal Children's Hospital of the MUHC, Montreal · Centre Hospitalier Universitaire Sainte-Justine, Montreal · Children'S Hospital Of Eastern Ontario, Ottawa · CHU de Quebec-Centre Hospitalier de l'Universite Laval (CHUL), Québec · Centre Hospitalier Universitaire de Sherbrooke-Fleurimont, Sherbrooke · Hospital for Sick Children, Toronto · British Columbia Children's Hospital, Vancouver · CancerCare Manitoba, Winnipeg
Registry updated 2026-08-25
NCT05702645
A Study to Learn More About the Health of Persons With Down Syndrome After Treatment for Acute Leukemia
Research · Children's Oncology Group
Children's Hospital, London
Registry updated 2026-08-25
NCT07301424
Subcutaneous Blinatumomab Plus Ponatinib for BCR-ABL+ B-ALL
Trial Treatment · Phase 2 · University of Alberta
University of Alberta, Edmonton
Registry updated 2026-08-12
NCT04877522
Asciminib Roll-over Study
Trial Treatment · Phase 4 · Novartis Pharmaceuticals
Montreal
Registry updated 2026-07-06
NCT05848687
TINI 2: Total Therapy for Infants With Acute Lymphoblastic Leukemia II
Trial Treatment · Phase 1/2 · Tanja Andrea Gruber
Alberta Children's Hospital, Calgary · Stollery Children'S Hospital, Edmonton · McMaster Children's Hospital, Hamilton · Montreal Children's Hospital, Montreal · CHU Sainte-Justine, Montreal · CHU de Quebec, Québec · BC Children ' s Hospital, Vancouver
Registry updated 2026-06-03
NCT01790152
Effects of Dexrazoxane Hydrochloride on Biomarkers Associated With Cardiomyopathy and Heart Failure After Cancer Treatment
Research · Children's Oncology Group
Alberta Children's Hospital, Calgary · McMaster Children's Hospital at Hamilton Health Sciences, Hamilton · Centre Hospitalier Universitaire Sainte-Justine, Montreal · The Montreal Children's Hospital of the MUHC, Montreal · Children'S Hospital Of Eastern Ontario, Ottawa · Centre hospitalier universitaire de Québec, Québec · Hospital for Sick Children, Toronto
Registry updated 2026-05-18
NCT07518654
Phase I Clinical Trial of ThINKK Adoptive Immunotherapy After Allogeneic Hematopoietic Transplantation in Children With Leukemia or Neuroblastoma
Trial Treatment · Phase 1 · Michel Duval
CHU Sainte-Justine, Montreal · The Hospital for Sick Children, Toronto
Registry updated 2026-04-08
NCT04988555
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
Trial Treatment · Phase 1/2 · Sumitomo Pharma America, Inc.
Tom Baker Cancer Center, Calgary · University of Alberta, Edmonton
Registry updated 2026-03-24
NCT06325280
Exercise MRI to Evaluate Cardiorespiratory Fitness in Children With Heart Disease
Research · University of Alberta
University of Alberta, Edmonton
Registry updated 2026-03-16
NCT05451979
HIIT in Pediatric Heart Transplant Recipients (MedBIKE™)
Trial Treatment · University of Alberta
University of Alberta, Edmonton
Registry updated 2026-03-13
NCT03938987
Anti-CD19, Dual Co-stimulatory (4-1BB, CD3ζ) Chimeric Antigen Receptor T-cells in Patients With Relapsed/Refractory Aggressive Lymphoma or Acute Lymphoblastic Leukemia (ALL)
Trial Treatment · Phase 1/2 · University of Alberta
Tom Baker Cancer Centre, Calgary · Alberta Children's Hospital, Calgary · Foothills Medical Centre, Calgary · Stollery Children'S Hospital, Edmonton · University of Alberta Hospital, Edmonton · Cross Cancer Institute, Edmonton
Registry updated 2026-02-09

All Acute lymphoblastic leukaemia trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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