Acute lymphoblastic leukaemia trials in Spain

In Spain 41 Also abroad 563

41 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

Phase 4Taking people
Asciminib Roll-over Study
Where
Badalona, Barcelona, Bilbao, L'Hospitalet de Llobregat, Madrid, Santa Cruz de Tenerife, Santiago de Compostela, Sevilla, Valencia
Age
7 years to 100 years
People
347 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT04877522 · EU 2023-507557-16-00
Phase 3Taking people
A Study of Fludarabine Dosing in Children and Young Adults With B-cell Acute Lymphoblastic Leukemia
Where
Esplugues de Llobregat
Age
1 year to 64 years
People
130 worldwide
Run by
Memorial Sloan Kettering Cancer Center
See details and how to joinNCT07223021 · EU 2025-523096-34-00
Phase 2Not yet taking people in Spain
Inotuzumab as Post-Trasplantation Therapy for Adult High-risk B-cell Precursor Acute Lymphoblastic Leukemia
Where
Badalona, Barcelona, Madrid, Málaga, Salamanca, San Sebastián, Santander, Seville, Valencia
Age
18 years and over
People
30
Run by
PETHEMA Foundation
See details and how to joinNCT07862946
Phase 1/2Taking people
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Where
Barcelona, Esplugues De Llobregat, Madrid, Valencia
Age
6 months to 25 years
People
90 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06395103 · EU 2023-507178-41-00
Phase 2/3Taking people
A Clinical Trial of MK-1045 in People With B-cell Acute Lymphoblastic Leukemia (MK-1045-005)
Where
Badalona, Madrid, Oviedo, Pozuelo de Alarcón, Salamanca, Valencia
Age
12 years and over
People
340 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07570173 · EU 2025-522267-15-00
Phase 3Taking people
International Study for Treatment of Childhood Relapsed Precursor B-Cell ALL 2020 (IntReALL BCP 2020)
Where
Alicante, Barakaldo, Barcelona, Esplugues de Llobregat, Madrid, Málaga, Murcia, Palma, Santiago de Compostela, Sevilla, Valencia, Zaragoza
Age
1 year to 64 years
People
750 worldwide
Run by
Charite University, Berlin, Germany
See details and how to joinNCT07476729 · EU 2023-509392-17-00
Phase 3Taking people
Interfant-21 Treatment Protocol for Infants Under 1 Year With KMT2A-rearranged ALL or Mixed Phenotype Acute Leukemia
Where
Barcelona, Madrid, Sevilla, Valencia
Age
1 day to 1 year
People
160 worldwide
Run by
Princess Maxima Center for Pediatric Oncology
See details and how to joinNCT05327894 · EU 2022-502503-30-00
Phase 1/2Taking people
Study of AZD4512 Monotherapy or in Combination With Anticancer Agents in Participants With Acute Lymphoblastic Leukemia
Where
Badalona, Barcelona, Salamanca, Santander
Age
12 years and over
People
83 worldwide
Run by
AstraZeneca
See details and how to joinNCT07109219 · EU 2025-522372-93-00
Phase 3Taking people
Single-arm Study of IgPro20 in Adults With Secondary Immune Deficiencies Due to Hematologic Malignancies Treated With B-cell Targeting Chimeric Antigen Receptor T-cell and T-cell Redirecting Therapies
Where
Badalona, Barcelona, Elche, Madrid, Santander
Age
18 years and over
People
63 worldwide
Run by
CSL Behring
See details and how to joinNCT07648264 · EU 2026-525626-38-00
Phase 1/2Taking people
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
Where
Barcelona, Madrid, Salamanca, Sevilla, Valencia
Age
12 years and over
People
255 worldwide
Run by
AstraZeneca
See details and how to joinNCT06137118 · EU 2023-505840-20-00
Phase 1/2Taking people
Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors
Where
Barcelona, Madrid, Valencia
Age
1 year to 17 years
People
70 worldwide
Run by
Incyte Biosciences International Sàrl
See details and how to joinNCT03934372 · EU 2023-509699-41-00
Phase 1/2Taking people
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
Where
L'Hospitalet de Llobregat, Sevilla, Valencia
Age
30 days and over
People
447 worldwide
Run by
Syndax Pharmaceuticals
See details and how to joinNCT04065399 · EU 2024-513759-34-00
Phase 1Taking people
A Study of CD19 Targeted CAR T Cell Therapy in Pediatric Patients With Relapsed or Refractory B Cell Acute Lymphoblastic Leukemia (B ALL) and Aggressive Mature B-cell Non-Hodgkin Lymphoma (B NHL)
Where
Barcelona, Madrid
Age
0 years to 18 years
People
30 worldwide
Run by
Autolus Limited
See details and how to joinNCT06173518 · EU 2023-506307-26-00
No phaseNot yet taking people in Spain
Digital Patient-Reported Assessment in Older Adults With Acute Leukemia
Where
Oviedo
Age
65 years and over
People
20
Run by
Fundación para la Investigación Biosanitaria del Principado de Asturias
See details and how to joinNCT07597590
Phase 1/2Not yet taking people in Spain
Study of the safety and efficacy of asciminib in pediatric and young adult participants with r/r Ph+ or ABL-class Ph-like ALL
Where
Barcelona, Esplugues de Llobregat, Madrid
Age
Up to 64 years
People
22 worldwide
Run by
Novartis Pharma AG
See details and how to join2025-522019-40-00 · EU 2025-522019-40-00
Phase 2Taking people
A Study to Learn More About the Study Medicine Called Inotuzumab Ozogamicin (InO) in Children (1 to <18 Years) With First Relapse ALL
Where
Barcelona, Esplugues de Llobregat, Madrid, Murcia, Santiago De Compostela, Sevilla, Valencia
Age
1 year to 17 years
People
100 worldwide
Run by
Pfizer
See details and how to joinNCT05748171 · EU 2023-509810-13-00
Phase 2Not yet taking people in Spain
A phase II clinical trial of inotuzumab ozogamicin as prophylaxis for relapse in patients with lymphoblastic leukaemia after allogeneic stem cell haemotopoietic transplantation
Where
Badalona, Barcelona, Donostia, Madrid, Málaga, Salamanca, Santander, Sevilla, Valencia
Age
18 years and over
People
30
Run by
Fundacion PETHEMA
See details and how to join2026-525964-17-00 · EU 2026-525964-17-00
Phase 2/3Taking people
Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
Where
Barcelona, Murcia, Oviedo
Age
1 month to 18 years
People
1,800 worldwide
Run by
St. Anna Kinderkrebsforschung
See details and how to joinNCT01949129 · EU 2024-512657-24-00
No phaseTaking people
A Treatment Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia
Where
Alicante, Barakaldo, Barcelona, Fuencarral-El Pardo, Madrid, Murcia, Palma de Mallorca, Santander, Santiago de Compostela, Seville, Valencia, Zaragoza
Age
0 years to 45 years
People
500 worldwide
Run by
Mats Heyman
See details and how to joinNCT03911128
Phase 3Taking people
A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia
Where
Barakaldo, Barcelona, Esplugues de Llobregat, Madrid, Palma, Sevilla, Valencia, Zaragoza
Age
0 years to 45 years
People
6,430 worldwide
Run by
Mats Heyman
See details and how to joinNCT04307576 · EU 2022-501050-11-01
Phase 1Taking people
A Phase I Clinical Trial of CART cell therapy for refractory/ relapsed acute lymphoblastic leukemia with unmet needs in children, adolescents and young adults: feasibility and safety study (REALL_CART)
Where
Madrid
Age
Up to 64 years
People
10
Run by
Fundacion Para La Investigacion Biomedica Del Hospital Universitario La Paz
See details and how to join2023-509723-41-01 · EU 2023-509723-41-01
Phase 2Not yet taking people in Spain
A PRECISION MEDICINE RANDOMIZED TRIAL FOR PATIENTS WITH RELAPSED OR REFRACTORY T-CELL ACUTE LYMPHOBLASTIC LEUKEMIA BASED ON A FUNCTIONAL APPROACH. ALL-TARGET TRIAL
Where
Badalona, Barcelona, Donostia, Madrid, Málaga, Murcia, Salamanca, Santander, Sevilla, Valencia
People
86 worldwide
Run by
Centre Hospitalier De Versailles
See details and how to join2024-516570-30-00 · EU 2024-516570-30-00
Phase 1/2Taking people
Inotuzumab ozogamicin for Acute Lymphoblastic Leukemia
Where
Barcelona, Esplugues De Llobregat, Madrid, Valencia
Age
Up to 17 years
People
142 worldwide
Run by
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
See details and how to join2023-504694-20-00 · EU 2023-504694-20-00
Phase 1/2Taking people
Phase I/IIa clinical trial with dose escalation to evaluate safety and efficacy of the infusion of CART84 in relapsed/refractory (R/R) acute myeloid leukemia (AML) and acute lymphoblastic T leukemia patients (T-ALL).
Where
Barcelona, Valencia
Age
18 years and over
People
39
Run by
Gyala Therapeutics S.L.
See details and how to join2024-519966-31-00 · EU 2024-519966-31-00
Phase 1/2Taking people
Single-center phase I/IIa study with CART cells produced using the anti-CD19 transposon technique (TranspoCART19) for patients with CD19+ acute lymphoblastic leukemia resistant or refractory to treatment
Where
Pamplona
People
24
Run by
Clinica Universidad De Navarra
See details and how to join2025-522673-11-00 · EU 2025-522673-11-00