Acute myeloid leukemia trials in Australia

In Australia 22 Also abroad 761

22 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
Bleximenib in Combination With Standard Induction and Consolidation Therapy Followed by Maintenance for Treatment of Patients With Acute Myeloid Leukemia (AML)
Where
Adelaide, Birtinya, Brisbane, Camperdown, Melbourne, Sydney
Age
18 years and over
People
875 worldwide
Run by
Stichting Hemato-Oncologie voor Volwassenen Nederland
See details and how to joinNCT07223814 · EU 2025-522767-15-00
Phase 1Enrolling by invitation
A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring
Where
Macquarie University, Melbourne, Nedlands, Randwick
Age
18 years and over
People
120 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06788509 · EU 2024-515457-21-00
Phase 3Taking people
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
Where
Bedford Park, Camperdown, Fitzroy, Kogarah, Melbourne, Woolloongabba
Age
18 years and over
People
600 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06852222 · EU 2024-520154-38-00
Phase 1Taking people
A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS
Where
Clayton, Fitzroy, Melbourne, Nedlands, Perth
Age
18 years and over
People
100 worldwide
Run by
Apollo Therapeutics Ltd
See details and how to joinNCT06372717
Phase 1/2Taking people
Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression
Where
Fitzroy, Perth
Age
16 years and over
People
85 worldwide
Run by
AstraZeneca
See details and how to joinNCT07155226 · EU 2025-521299-76-00
Phase 3Taking people
Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation
Where
Douglas, Gosford, Kingswood, Kogarah, Melbourne, Nedlands, Parkville, Perth, Randwick, South Brisbane, Wollongong
Age
12 years and over
People
468 worldwide
Run by
Syndax Pharmaceuticals
See details and how to joinNCT07211958 · EU 2025-522279-27-00
Phase 3Taking people
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
Where
Heidelberg, Kurralta Park, Melbourne, Murdoch, Waratah
Age
18 years and over
People
1,300 worldwide
Run by
Kura Oncology, Inc.
See details and how to joinNCT07007312 · EU 2025-521314-25-00
Phase 1/2Taking people
A Study of Revumenib in R/R Leukemias Including Those With an MLL/KMT2A Gene Rearrangement or NPM1 Mutation
Where
Melbourne, Nedlands, Parkville, Saint Leonards
Age
30 days and over
People
447 worldwide
Run by
Syndax Pharmaceuticals
See details and how to joinNCT04065399 · EU 2024-513759-34-00
Phase 1Taking people
A Study to Assess Adverse Events and How Intravenous (IV) Pivekimab Sunirine Moves Through the Body in Pediatric Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)
Where
Perth, Westmead
Age
6 months to 17 years
People
18 worldwide
Run by
AbbVie
See details and how to joinNCT07306832
Phase 3Taking people
A Study to Compare Standard Chemotherapy to Therapy With CPX-351 and/or Gilteritinib for Patients With Newly Diagnosed AML With or Without FLT3 Mutations
Where
Perth, Randwick, South Brisbane, Westmead
Age
6 months to 21 years
People
1,400 worldwide
Run by
Children's Oncology Group
See details and how to joinNCT04293562
Phase 2Taking people
Evaluation of Two Dose Levels of Quizartinib as Maintenance in FLT3-ITD (+) Acute Myeloid Leukemia Patients in Complete Remission
Where
Adelaide, Australia, Darlinghurst, Melbourne, Perth, Southport, Sydney
Age
18 years and over
People
130 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06824168
Phase 2Taking people
(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
Where
Kingswood, Melbourne N., Southport
Age
18 years and over
People
140 worldwide
Run by
Cogent Biosciences, Inc.
See details and how to joinNCT04996875 · EU 2024-511407-42-00
Phase 1/2Taking people
A Study of BGB-11417 in Participants With Myeloid Malignancies
Where
Clayton, Concord, Fitzroy, Heidelberg, Kogarah, Melbourne, Murdoch, Nedlands, Orange, Southport
Age
18 years and over
People
260 worldwide
Run by
BeOne Medicines
See details and how to joinNCT04771130 · EU 2023-508881-14-00
Phase 3Taking people
Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML
Where
Adelaide, Birtinya, Brisbane, Douglas, Melbourne, Perth, Sydney
Age
18 years and over
People
448 worldwide
Run by
Stichting Hemato-Oncologie voor Volwassenen Nederland
See details and how to joinNCT06652438 · EU 2024-512733-32-00
Phase 1/2Taking people
The Pediatric Acute Leukemia (PedAL) Screening Trial - A Study to Test Bone Marrow and Blood in Children With Leukemia That Has Come Back After Treatment or Is Difficult to Treat - A Leukemia & Lymphoma Society and Children's Oncology Group Study
Where
Parkville, Perth, South Brisbane, Westmead
Age
Up to 22 years
People
960 worldwide
Run by
PedAL BCU, LLC
See details and how to joinNCT04726241
Phase 1Taking people
ICP-248 in Combination With Azacitidine for the Treatment in Patients With Myeloid Malignancies
Where
Perth, Sydney
Age
18 years and over
People
266 worldwide
Run by
Beijing InnoCare Pharma Tech Co., Ltd.
See details and how to joinNCT06656494
Phase 1/2Taking people
Study to Evaluate the Safety and Tolerability of EP0042
Where
Perth
Age
18 years and over
People
70 worldwide
Run by
Ellipses Pharma
See details and how to joinNCT04581512 · EU 2024-514588-24-00
Phase 1Taking people
Combined Evaluation of Epigenetic and Sensitising Therapy in AML and MDS
Where
Sydney, Westmead
Age
18 years and over
People
12
Run by
Clinical Hub for Interventional Research (CHOIR)
See details and how to joinNCT05636514
Phase 1Taking people
Dose Escalation and Expansion Study to Evaluate the Safety, PK, PD and Efficacy of ZE46-0134 in Adults With FLT3 Mutated or Spliceosome Mutated Relapsed or Refractory Acute Myeloid Leukemia
Where
Melbourne, Perth
Age
18 years and over
People
150 worldwide
Run by
Lomond Therapeutics Holdings, Inc.
See details and how to joinNCT06366789
No phaseTaking people
Evaluation of Combined Sensitising and Hypomethylating Therapy Outcomes in AML PDX
Where
Canberra, Sydney, Westmead
Age
18 years and over
People
25
Run by
Clinical Hub for Interventional Research (CHOIR)
See details and how to joinNCT06782971
Phase 1/2Taking people
Clinical Trial to Evaluate the Safety, Tolerability, Pharmacokinetics and Pharmacodynamics of Tuspetinib (HM43239) in Patients With Relapsed or Refractory Acute Myeloid Leukemia
Where
Albury, Fitzroy, Herston, Nedlands, Townsville
Age
18 years and over
People
240 worldwide
Run by
Aptose Biosciences Inc.
See details and how to joinNCT03850574 · EU 2023-503244-14-00
Phase 1Taking people
A Study of PEP07 (Checkpoint Kinase 1 Inhibitor) in Patients With Advanced Cancer
Where
Clayton
Age
18 years and over
People
32 worldwide
Run by
PharmaEngine
See details and how to joinNCT05659732