Acute myeloid leukemia trials in United Kingdom
24 trials · From ClinicalTrials.gov, checked 10 Nov 2026. Ask the study team whether a trial fits you.
Phase 1RecruitingTrial-stage medicine
A Study of CHM-029 in Participants With NPM1 Mutated, KMT2A or NUP98 Rearranged AML
- Where
- Manchester, Oxford, Wales
- Age
- 18 years and over
- People
- 40 worldwide
- Run by
- Charm Therapeutics
See details and how to joinNCT07751991EU 2026-526409-14-00Registry updated 2026-11-06
Phase 1Enrolling by invitationTrial-stage medicine
A Rollover Study for Continued Study Treatment and Ongoing Safety Monitoring
- Where
- Leicester, London, Plymouth
- Age
- 18 years and over
- People
- 120 worldwide
- Run by
- Janssen Research & Development, LLC
See details and how to joinNCT06788509EU 2024-515457-21-00Registry updated 2026-11-04
Phase 3RecruitingTrial-stage medicine
A Study of Bleximenib, Venetoclax and Azacitidine For Treatment of Participants With Newly Diagnosed Acute Myeloid Leukemia (AML)
- Where
- Brighton, Cambridge, Canterbury, Colchester, Edinburgh, Liverpool, London, Plymouth, Worthing
- Age
- 18 years and over
- People
- 600 worldwide
- Run by
- Janssen Research & Development, LLC
See details and how to joinNCT06852222EU 2024-520154-38-00Registry updated 2026-11-03
Phase 1RecruitingTrial-stage medicine
Phase 1 Open-label Study of AMX-883 Alone in Participants With AML and High-risk MDS and in Combination in Participants With AML
- Where
- Manchester
- Age
- 18 years and over
- People
- 54 worldwide
- Run by
- Amphista Therapeutics Ltd
See details and how to joinNCT07723703Registry updated 2026-11-02
Phase 3RecruitingTrial-stage medicine
Mocravimod as Adjunctive and Maintenance Treatment in AML Patients Undergoing Allo-HCT
- Where
- Birmingham, Cardiff, Glasgow, London, Manchester, Newcastle upon Tyne, Nottingham, Oxford, Sheffield
- Age
- 18 years to 75 years
- People
- 366 worldwide
- Run by
- Priothera SAS
See details and how to joinNCT05429632Registry updated 2026-10-30
Phase 1RecruitingTrial-stage medicine
A Study to Investigate APL-4098 Alone and in Combination in Adults With AML or MDS
- Where
- Cardiff, Glasgow, London
- Age
- 18 years and over
- People
- 100 worldwide
- Run by
- Apollo Therapeutics Ltd
See details and how to joinNCT06372717Registry updated 2026-10-28
Phase 1/2RecruitingTrial-stage medicine
Study of AZD3632 Monotherapy or in Combination With Anticancer Agents in Participants With Advanced Haematologic Malignancies With KMT2Ar, NPM1m, or Other Genotypes Associated With HOX Overexpression
- Where
- Edinburgh, London, Manchester, Newcastle
- Age
- 16 years and over
- People
- 85 worldwide
- Run by
- AstraZeneca
See details and how to joinNCT07155226EU 2025-521299-76-00Registry updated 2026-10-23
Phase 3RecruitingTrial-stage medicine
Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation
- Where
- Aberdeen, Derby, Leicester, Lincoln, London, Oxford, Southampton, Sutton
- Age
- 12 years and over
- People
- 468 worldwide
- Run by
- Syndax Pharmaceuticals
See details and how to joinNCT07211958EU 2025-522279-27-00Registry updated 2026-10-21
Phase 3RecruitingTrial-stage medicine
Studies to Assess Ziftomenib in Combination With Ven+Aza or 7+3 in Patients With Untreated NPM1-m or KMT2A-r AML
- Where
- London
- Age
- 18 years and over
- People
- 1,300 worldwide
- Run by
- Kura Oncology, Inc.
See details and how to joinNCT07007312EU 2025-521314-25-00Registry updated 2026-10-13
Phase 1/2RecruitingTrial-stage medicine
Safety and Efficacy of Ponatinib for Treatment of Pediatric Recurrent or Refractory Leukemias, Lymphomas or Solid Tumors
- Where
- Glasgow, Liverpool, Sutton
- Age
- 1 year to 17 years
- People
- 70 worldwide
- Run by
- Incyte Biosciences International Sàrl
See details and how to joinNCT03934372EU 2023-509699-41-00Registry updated 2026-10-09
Phase 2/3RecruitingTrial-stage medicine
A Multi-phase Study of ASTX030 (Azacitidine and Cedazuridine) in Myeloid Neoplasm Alone or in Combination With Venetoclax in AML (AZTOUND Study)
- Where
- London, Maidstone, Manchester, Oxford, Southampton
- Age
- 18 years and over
- People
- 316 worldwide
- Run by
- Taiho Oncology, Inc.
See details and how to joinNCT04256317EU 2024-515098-93-00Registry updated 2026-10-06
Phase 1RecruitingTrial-stage medicine
A Study to Assess Adverse Events and How Intravenous (IV) Pivekimab Sunirine Moves Through the Body in Pediatric Participants With Relapsed or Refractory Acute Myeloid Leukemia (AML)
- Where
- Cambridge
- Age
- 6 months to 17 years
- People
- 18 worldwide
- Run by
- AbbVie
See details and how to joinNCT07306832Registry updated 2026-10-05
Phase 2RecruitingTrial-stage medicine
(Apex) Bezuclastinib in Patients With Advanced Systemic Mastocytosis
- Where
- Leeds, London
- Age
- 18 years and over
- People
- 140 worldwide
- Run by
- Cogent Biosciences, Inc.
See details and how to joinNCT04996875EU 2024-511407-42-00Registry updated 2026-09-15
Phase 1/2RecruitingTrial-stage medicine
A Study of BGB-11417 in Participants With Myeloid Malignancies
- Where
- Edinburgh, Greater Manchester
- Age
- 18 years and over
- People
- 260 worldwide
- Run by
- BeOne Medicines
See details and how to joinNCT04771130EU 2023-508881-14-00Registry updated 2026-09-14
Phase 3RecruitingTrial-stage medicine
Revumenib in Combination With Azacitidine + Venetoclax in Patients NPM1-mutated or KMT2A-rearranged AML
- Where
- Belfast, Birmingham, Blackpool, Bodelwyddan, Bristol, Cardiff, Cosham, Coventry, Derby, Edinburgh, Glasgow, Harrow, Hull, Leeds, Leicester, London, Manchester, Newcastle, Nottingham, Oxford, Southampton, Stoke-on-Trent, Sutton, Swindon, Truro, Wolverhampton
- Age
- 18 years and over
- People
- 448 worldwide
- Run by
- Stichting Hemato-Oncologie voor Volwassenen Nederland
See details and how to joinNCT06652438EU 2024-512733-32-00Registry updated 2026-09-02
Phase 1/2RecruitingTrial-stage medicine
Study to Evaluate CCS1477 (Inobrodib) in Haematological Malignancies
- Where
- Bebington, Bristol, Cardiff, Derby, Edinburgh, Glasgow, Leicester, London, Manchester, Newcastle upon Tyne, Nottingham, Oxford, Southampton, Stoke-on-Trent, Sutton
- Age
- 18 years and over
- People
- 250 worldwide
- Run by
- CellCentric Ltd.
See details and how to joinNCT04068597Registry updated 2026-06-24
Phase 1/2RecruitingTrial-stage medicine
Study to Evaluate the Safety and Tolerability of EP0042
- Where
- London, Manchester
- Age
- 18 years and over
- People
- 70 worldwide
- Run by
- Ellipses Pharma
See details and how to joinNCT04581512EU 2024-514588-24-00Registry updated 2026-06-22
Phase 2RecruitingTrial-stage medicine
Methods of T Cell Depletion Trial (MoTD)
- Where
- Birmingham, Bristol, Cambridge, Cardiff, Glasgow, Leeds, London, Manchester, Newcastle upon Tyne, Nottingham, Oxford, Plymouth, Sheffield, Sutton
- Age
- 16 years to 70 years
- People
- 400
- Run by
- University of Birmingham
See details and how to joinNCT04888741Registry updated 2026-05-05
No phaseRecruitingResearch participation
WearAble Technology for Collecting Health Data in People Who Are the Transfused (WATCH Transfused) - A UK Exploratory Study to Improve Quality of Life and the Efficacy of Transfusion Supportive Care in People With Blood Cancers Undergoing Treatment
- Where
- Oxford
- Age
- 18 years and over
- People
- 80
- Run by
- University of Oxford
See details and how to joinNCT07511829Registry updated 2026-04-06
Phase 1/2RecruitingTrial-stage medicine
A Phase 1/2 Study of Enzomenib (DSP-5336) in Patients With Acute Leukemia (Horizen-1)
- Where
- Birmingham, Bristol, Edinburgh, London, Manchester, Oxford, Stoke-on-Trent, Sutton
- Age
- 12 years and over
- People
- 606 worldwide
- Run by
- Sumitomo Pharma America, Inc.
See details and how to joinNCT04988555Registry updated 2026-03-24
Phase 1/2Not yet recruitingTrial-stage medicine
GRanulocyte Augmented Cord Blood Transplantation for Poor Risk leukaEmia
- Where
- London, Manchester
- Age
- 16 years to 55 years
- People
- 50
- Run by
- University of Manchester
See details and how to joinNCT07372885Registry updated 2026-03-11
Phase 3RecruitingTrial-stage medicine
Ivosidenib and Azacitidine With or Without Venetoclax in Adult Patients With Newly Diagnosed IDH1-Mutated AML or MDS/AML Considered Ineligible for Intensive Chemotherapy
- Where
- Birmingham, Blackpool, Bristol, Cardiff, Glasgow, Leeds, Leicester, London, Manchester, Newcastle upon Tyne, Nottingham, Oxford, Portsmouth, Southampton, Wolverhampton
- Age
- 18 years and over
- People
- 227 worldwide
- Run by
- Stichting Hemato-Oncologie voor Volwassenen Nederland
See details and how to joinNCT07075016Registry updated 2025-08-19
Phase 2RecruitingTrial-stage medicine
Intestinal Microbiota Transplant Prior to Allogeneic Stem Cell Transplant (MAST) Trial
- Where
- Birmingham, Leeds, London, Manchester
- Age
- 18 years and over
- People
- 50
- Run by
- Imperial College London
See details and how to joinNCT06355583Registry updated 2025-04-17
No phaseRecruitingResearch participation
Gut Health in Children With Cancer
- Where
- London
- Age
- 1 month to 16 years
- People
- 40
- Run by
- Great Ormond Street Hospital for Children NHS Foundation Trust
See details and how to joinNCT06899581Registry updated 2025-03-28
All Acute myeloid leukemia trials and the map
This page is not medical advice. Talk to your doctor before contacting a trial.