ALS (motor neurone disease): open trials in United States

89 open trials have a site in United States. Registry data; only the trial team decides who can take part.

NCT02567136
Imaging Biomarkers in ALS
Research · University of Minnesota
University of Minnesota, Minneapolis
Registry updated 2025-12-02
NCT06094205
Feasibility of the BrainGate2 Neural Interface System in Persons With Tetraplegia (BG-Speech-02)
Trial Treatment · Leigh R. Hochberg, MD, PhD.
University of California - Davis, Sacramento
Registry updated 2025-12-01
NCT05137665
Target ALS Biomarker Study; Longitudinal Biofluids, Clinical Measures, and At Home Measures
Research · Target ALS Foundation, Inc.
Massachusetts General Hospital, Boston · Northwestern University, Chicago · Georgetown University, Georgetown · Baylor College of Medicine, Houston · Mayo Clinic, Jacksonville · Columbia University, New York · Barrow Neurological Institute, Phoenix · University of California San Diego, San Diego · University of Washington, Seattle · Washington University, St Louis
Registry updated 2025-11-21
NCT06968468
Resiliency Intervention for Patients With ALS and Their Care-Partners
Trial Treatment · Massachusetts General Hospital
Massachusetts General Hospital, Boston
Registry updated 2025-11-17
NCT07224256
VOICE: An Early Feasibility Study of a Precise Robotically Implanted Brain-Computer Interface for Communication Restoration
Trial Treatment · Neuralink Corp
The University of Texas Southwestern Medical Center, Dallas
Registry updated 2025-11-04
NCT07209943
Augmented Reality BCI Longitudinal Study for Persons With ALS, Stroke, TBI and SCI Utilizing Cognixion + Apple Vision Pro
Trial Treatment · Cognixion
Cognixion HQ, Santa Barbara
Registry updated 2025-10-07
NCT03127267
Efficacy and Safety of Masitinib Versus Placebo in the Treatment of ALS Patients
Trial Treatment · Phase 3 · AB Science
Johns Hopkins Medicine Brain Science Institute, Baltimore · University of Alabama at Birmingham, Birmingham · Lahey Hospital and Medical Center, Burlington · University of Virginia Health System, Charlottesville · University of Kentucky, Lexington · University of Southern California, Los Angeles
Registry updated 2025-09-12
NCT07169175
A Phase Ⅰ/Ⅱa Study of SNUG01 in Adult Subjects With ALS
Trial Treatment · Phase 1/2 · SineuGene Therapeutics Co., Ltd.
Massachusetts General Hospital, Boston
Registry updated 2025-09-11
NCT06710626
Control of Assistive Devices Via Brain-Computer Interface Technology
Trial Treatment · Neuralink Corp
Barrow Neurological Institute, Phoenix
Registry updated 2025-06-05
NCT06973629
Efficacy and Safety of MSC-NTF (NurOwn) in Participants With Early Symptomatic ALS and Moderate Disease Presentation in ALS (ENDURANCE STUDY)
Trial Treatment · Phase 3 · Brainstorm-Cell Therapeutics
University of Colorado Anschutz Medical Campus School of Medicine, Aurora · Sean M. Healey & AMG Center for ALS at Massachusetts General Hospital, Boston · Northwestern Medicine, Chicago · Nova Southeastern University, Davie · Mayo Clinic, Jacksonville · University of California San Diego Medical Center, La Jolla · University of Southern California, Los Angeles · Temple University Of the Commonwealth System of Higher Education, Philadelphia · Barrow Neurological Institute, Phoenix · Providence ALS Center, Portland · Mayo Clinic, Rochester · University of California San Francisco, San Francisco · California Pacific Medical Center, San Francisco · University of South Florida, Tampa · University of Massachusetts Medical School, Worcester
Registry updated 2025-05-22
NCT05395624
Safety, PK and Biodistribution of 18F-OP-801 in Patients With ALS, AD, MS, PD and Healthy Volunteers
Trial Treatment · Phase 1/2 · Ashvattha Therapeutics, Inc.
Mayo Clinic- Jacksonville, Jacksonville · UCSF, San Francisco · Stanford University, Stanford
Registry updated 2025-05-02
NCT06885918
ALS Research Collaborative
Research · ALS Therapy Development Institute
ALS Therapy Development Institute, Watertown
Registry updated 2025-03-20
NCT06203106
NYSCF Scientific Discovery Biobank
Research · New York Stem Cell Foundation Research Institute
New York Stem Cell Foundation Research Institute, New York
Registry updated 2025-03-03
NCT06810219
Augmented Reality BCI Longitudinal Study for Persons With Late Stage ALS
Trial Treatment · Cognixion
Cognixion, Santa Barbara
Registry updated 2025-02-05

All ALS (motor neurone disease) trials and the map

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