Alzheimer disease trials in Czechia

In Czechia 19 Also abroad 815

19 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
InRAD Observational Study
Where
Prague
Age
18 years and over
People
50,000 worldwide
Run by
Stichting International Registry for Alzheimer's Disease and other Dementias Foundation
See details and how to joinNCT07213700
Phase 2/3Taking people
Safety and Efficacy of EXV-802 and EXV-801 in the Treatment of Agitation in Alzheimer's Disease Dementia
Where
Brno-Stred, Kladno, Plzen, Praha, Prazske Predmesti
Age
55 years to 90 years
People
300 worldwide
Run by
Exciva GmbH
See details and how to joinNCT07284472 · EU 2024-517388-22-00
Phase 2/3Taking people
ACP-204 in Adults With Alzheimer's Disease Psychosis
Where
Brno-Stred, Choceň, Kladno, Prague, Prague 10, Rychnov nad Kněžnou
Age
55 years to 95 years
People
1,074 worldwide
Run by
ACADIA Pharmaceuticals Inc.
See details and how to joinNCT06159673 · EU 2023-507325-42-00
Phase 3Enrolling by invitation
ACP-204 in Adults With Alzheimer's Disease Psychosis Open Label Extension Study
Where
Brno-Stred, Choceň, Kladno, Prague, Prague 10, Rychnov nad Kněžnou
Age
55 years to 95 years
People
752 worldwide
Run by
ACADIA Pharmaceuticals Inc.
See details and how to joinNCT06194799 · EU 2023-507351-29-00
Phase 2Taking people
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Psychosis Associated With Alzheimer's Disease
Where
Brno, Hradec Králové, Prague
Age
55 years and over
People
370 worldwide
Run by
Intra-Cellular Therapies, Inc.
See details and how to joinNCT06540833
Phase 2Taking people
A Study to Assess the Efficacy and Safety of ITI-1284 in the Treatment of Agitation Associated With Alzheimer's Dementia
Where
Brno-Stred, Choceň, Plzen 3, Prague, Prague 10, Prague 6
Age
55 years and over
People
320 worldwide
Run by
Intra-Cellular Therapies, Inc.
See details and how to joinNCT06651567 · EU 2024-514680-26-00
Phase 3Taking people
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease
Where
Brno-Líšeň, Choceň, Olomouc, Plzen 3, Prague, Prague 6, Rychnov nad Kněžnou
Age
55 years to 90 years
People
426 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07011745 · EU 2025-520612-34-00
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease
Where
Brno-Líšeň, Olomouc, Plzen 3, Prague, Prague 6, Rychnov nad Kněžnou
Age
60 years to 85 years
People
586 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06976216 · EU 2025-520746-30-00
Phase 3Taking people
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
Where
Plzen 3, Prague, Prague 10, Rychnov nad Kněžnou
Age
55 years to 90 years
People
1,000 worldwide
Run by
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
See details and how to joinNCT05980949 · EU 2023-504151-27-00
Phase 3Taking people
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
Where
Brno-Líšeň, Choceň, Olomouc, Plzen 3, Prague, Prague 6, Rychnov nad Kněžnou
Age
55 years to 90 years
People
650 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06937229 · EU 2024-519994-20-00
No phaseTaking people
The Effect of Urolithin A (Mitopure®) on Alzheimer's Disease
Where
Prague
Age
55 years to 85 years
People
60
Run by
University Hospital, Akershus
See details and how to joinNCT07842146
Phase 2Taking people
A Study to Assess the Efficacy and Safety of ML-007C-MA for the Treatment of Alzheimer's Disease Psychosis
Where
Brno-Stred, Choceň, Pardubice I, Prague
Age
55 years to 90 years
People
300 worldwide
Run by
MapLight Therapeutics
See details and how to joinNCT06887192 · EU 2024-519820-26-00
Phase 2Taking people
A study to assess the efficacy and safety of ITI-1284 in the treatment of Psychosis Associated with Alzheimer's Disease
Where
Brno-Líšeň, Brno-Stred, Hradec Králové
Age
18 years and over
People
216 worldwide
Run by
Intra-Cellular Therapies Inc.
See details and how to join2024-513035-25-00 · EU 2024-513035-25-00
Phase 3Taking people
A Study to Assess Efficacy and Safety of KarXT for the Treatment of Psychosis Associated With Alzheimer's Disease (ADEPT-1)
Where
Brno, Kutná Hora, Pilsen, Prague, Rychnov nad Kněžnou
Age
55 years to 90 years
People
410 worldwide
Run by
Karuna Therapeutics, Inc., a Bristol Myers Squibb company
See details and how to joinNCT05511363
Phase 2Enrolling by invitation
An Open-Label Study of ML-007C-MA in Adults With Alzheimer's Disease Psychosis
Where
Brno-Stred, Choceň, Pardubice I, Prague
Age
55 years to 91 years
People
210 worldwide
Run by
MapLight Therapeutics
See details and how to joinNCT07459660 · EU 2025-521757-16-00
No phaseEnrolling by invitation
Telemedicine Self-examination of Speech and Memory for Rapid Detection of Cognitive Impairments Using Machine Learning Methods
Where
Pilsen, Prague
Age
40 years and over
People
500
Run by
Faculty Hospital Kralovske Vinohrady
See details and how to joinNCT07558785
Phase 1/2Taking people
A Study to Assess Safety and Tolerability and to Explore Efficacy of NSC001 in Mild to Moderate Alzheimer's Disease
Where
Brno-Líšeň, Prague, Rychnov nad Kněžnou
Age
50 years to 85 years
People
90 worldwide
Run by
NSC-Therapeutics
See details and how to joinNCT06995573 · EU 2024-518563-35-00
No phaseNot yet taking people in Czechia
Yoga-based, Movement Therapy Device as Noninvasive Glymphatic Clearance Augmentation in Alzheimer's Disease.
Where
Brno, Prague
Age
55 years and over
People
60 worldwide
Run by
CIATRIX, INC.
See details and how to joinNCT06989242
No phaseTaking people
Lifestyle for the BRAin Health - Time Restricted Eating and Mindfulness
Where
Brno
Age
60 years to 80 years
People
48
Run by
St. Anne's University Hospital Brno, Czech Republic
See details and how to joinNCT07042087