Alzheimer disease: open trials in Japan

21 open trials have a site in Japan. Registry data; only the trial team decides who can take part.

NCT07011732
A Phase 3 Study to Evaluate the Safety and Efficacy of KarXT + KarX-EC for the Treatment of Agitation Associated With Alzheimer's Disease (ADAGIO-1)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Nippon Medical School Hospital, Bunkyo-ku · Kuramitsu Hospital, Fukuoka · Hatano Kousei Hospital, Hadano · National Hospital Organization Hizen Psychiatric Center, Kanzaki-Gun Yoshinogari-Cho · Rainbow and Sea Hospital, Karatsu-shi · Teikyo University Mizonokuchi Hospital, Kawasaki · Okayama City General Medical Center Okayama City Hospital, Okayama · Asakayama Hospital, Sakai · Jichi Medical University Hospital, Shimotsuke-shi, Tochigi
Registry updated 2026-11-06
NCT07717411
A Study of Trontinemab in Cognitively Unimpaired Individuals at Risk for Progression to Symptomatic Alzheimer's Disease
Trial Treatment · Phase 3 · Hoffmann-La Roche
National Center for Geriatrics and Gerontology, Aichi · Kobe University Hospital, Hyōgo · Higashi Shinjuku Clinic, Tokyo · Medical Corporation Asbo Tokyo Asbo Clinic, Tokyo · Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo · Tokyo Medical University Hospital, Tokyo · Clinical Research Hospital Tokyo, Tokyo
Registry updated 2026-11-06
NCT07787169
A Master Protocol Studying Multiple Amyloid-Targeting Therapies in Healthy Participants and Participants With Alzheimer's Disease
Trial Treatment · Phase 1 · Eli Lilly and Company
The University of Tokyo Hospital, Bunkyō City · National Center for Geriatrics and Gerontology, Ōbu
Registry updated 2026-11-05
NCT07589595
A Study of Donanemab (LY3002813) in Participants With Early Cognitive Decline (TRAILBLAZER-ALZ 7)
Trial Treatment · Phase 2 · Eli Lilly and Company
Memory Clinic Ochanomizu, Bunkyō City · Shonan Keiiku Hospital, Fujisawa · Hyogo Prefectural Harima-Himeji General Medical Center, Himeji · Inage Neurology and Memory Clinic, Inage · Nippon Medical School Musashi Kosugi Hospital, Kawasaki · St. Marianna University Hospital, Kawasaki · Kobe University Hospital, Kobe · Juntendo Tokyo Koto Geriatric Medical Center, Kōtoku · KATAYAMA medical Clinic, Kurashiki · Nagoya Ekisaikai Hospital, Nagoya · Nagoya University Hospital, Nagoya · National Center for Geriatrics and Gerontology, Ōbu · The University of Osaka Hospital, Suita · Tokyo Metropolitan Institute for Geriatrics and Gerontology, tabashi City · Tachikawa Hospital, Tachikawa · Memory Clinic Toride, Toride · Yokohama Minami Kyosai Hospital, Yokohama · Oita University Hospital, Yufu
Registry updated 2026-11-04
NCT06297590
A First-In-Human Study of LY3954068 in Participants With Early Symptomatic Alzheimer's Disease
Trial Treatment · Phase 1 · Eli Lilly and Company
The University of Tokyo Hospital, Bunkyō City
Registry updated 2026-10-29
NCT07602582
A Study of Donanemab (LY3002813) in Participants Who Completed Study AACM (TRAILBLAZER-ALZ 3-EXT).
Trial Treatment · Phase 3 · Eli Lilly and Company
Tokyo-Eki Center-building Clinic, Chūōku · P-One Clinic, Hachiōji · National Center for Geriatrics and Gerontology, Ōbu · Samoncho Clinic, Shinjuku · Yotsuya Internal Medicine Clinic, Shinjyuku · Tokyo Metropolitan Institute for Geriatrics and Gerontology, tabashi City
Registry updated 2026-10-28
NCT06585787
A Study to Evaluate KarXT as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-4)
Trial Treatment · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Fukuoka · Hachiōji · Hatano Kousei Hospital, Hadano · Hyogo Prefectural Harima-Himeji General Medical Center, Himeji-Shi · Funairi nou clinic, Hiroshima · Iizuka · Kanzaki-Gun Yoshinogari-Cho · Koukan Clinic, Kawasaki-Shi · Southern TOHOKU Medical Clinic, Kōriyama · Yuge Neuropsychiatric Hospital, Kumamoto · National Hospital Organization Utano National Hospital, Kyoto · Asakayama General Hospital, Sakai · Sapporo · Tokyo Metropolitan Matsuzawa Hospital, Setagaya-Ku · Kurumi Clinic, Setagaya-Ku · Sangenjaya Nakamura Mental Clinic, Setagaya-Ku · Takamatsu · Shin-Abuyama Hospital, Takatsuki · Tsutsujimental Hospital, Tatebayashi · Memory clinic Toride, Toride-shi · Tsu · Wako-Shi · Yokohama City Minato Red Cross Hospital, Yokohama · Yokohama City University Hospital, Yokohama · Yokohama · Yoshinogawa
Registry updated 2026-10-27
NCT07787182
A Study of LY4405094 in Healthy Participants and Participants With Alzheimer's Disease
Trial Treatment · Phase 1 · Eli Lilly and Company
The University of Tokyo Hospital, Bunkyō City · National Center for Geriatrics and Gerontology, Ōbu
Registry updated 2026-10-22
NCT06875986
REXULTI General Use Results Survey in Patients With Hyperactivity, or Aggressive Behavior Associated With Alzheimer's Dementia
Research · Otsuka Pharmaceutical Co., Ltd.
Pharmacovigilance Department, Osaka
Registry updated 2026-10-20
NCT07033494
A Clinical Study of MK-2214 in People With Early Alzheimer's Disease (MK-2214-004)
Trial Treatment · Phase 2 · Merck Sharp & Dohme LLC
Inage Neurology and Memory Clinic (Site 9001), Chiba · Kyushu University Hospital (Site 9010), Fukuoka · Hatsuta Neurology Clinic (Site 9017), Hirakata · National Hospital Organization Hizen Psychiatric Medical Center (Site 9004), Kanzaki-gun · Association of Healthcare Corporation Koukankai Koukan Clinic (Site 9016), Kawasaki · Katayama Medical Clinic (Site 9005), Kurashiki · Chibaken Saiseikai Narashino Hospital (Site 9000), Narashino · National Center for Geriatrics and Gerontology (Site 9002), Ōbu · Okayama City General Medical Center Okayama City Hospital (Site 9008), Okayama · Tokyo Medical University Hospital (Site 9003), Shinjuku · Mie University Hospital (Site 9011), Tsu
Registry updated 2026-10-20
NCT07177352
Screening Study to Determine Individuals With Potential Trial Eligibility for Alzheimer's Disease Studies
Trial Treatment · Phase 3 · Hoffmann-La Roche
National Center for Geriatrics and Gerontology, Aichi · National Hospital Organization Hiroshima-Nishi Medical Center, Hiroshima · Brain Attack Center Ota Memorial Hospital, Hiroshima · Kobe University Hospital, Hyōgo · Kagawa University Hospital, Kagawa · Yokohama City Minato Red Cross Hospital, Kanagawa · Kochi Medical School Hospital, Kochi · National Hospital Organization Utano National Hospital, Kyoto · Kyoto University Hospital, Kyoto · Mishuku Hospital, Meguro-Ku · Mie University Hospital, Mie · Okayama City Hospital, Okayama · Rijikai Medical Corporation Katayama Medical Clinic, Okayama · Kotobuki Social Medical Corporation Tominaga Clinic, Osaka · Iwata Neurosurgery Clinic, Osaka · Medical Corporation Heishinkai OCROM Clinic, Osaka · Tokyo Metropolitan Institute for Geriatrics and Gerontology, Tokyo · Keio University Hospital, Tokyo · Clinical Research Hospital Tokyo, Tokyo · Federation of National Public Service Personnel Mutual Aid Associations Tachikawa Hospital, Tokyo · National Center of Neurology and Psychiatry, Tokyo · Tokyo Medical University Hospital, Tokyo · Memory Clinic Ochanomizu, Tokyo · Higashi Shinjuku Clinic, Tokyo · P-One Clinic, Tokyo · The University of Tokyo Hospital, Tokyo · Medical Corporation Asbo Tokyo Asbo Clinic, Tokyo · Yamagata Tokusyukai Hospital, Yamagata
Registry updated 2026-10-19
NCT05980949
Open-Label Extension Study to Assess the Long-Term Safety and Tolerability of KarXT in Subjects With Psychosis Associated With Alzheimer's Disease (ADEPT-3)
Trial Treatment · Phase 3 · Karuna Therapeutics, Inc., a Bristol Myers Squibb company
Hachiōji · Hadano · Himeji-Shi · Funairi nou clinic, Hiroshima · Iizuka · Local Institution - 1-13H98LYW, Iizuka · Koukan Clinic, Kawasaki-Shi · Kōriyama · Kumamoto · Local Institution - 1-13H98LTZ, Kumamoto · National Hospital Organization Utano National Hospital, Kyoto · Asakayama General Hospital, Sakai · Sapporo · Setagaya-Ku · Kurumi Clinic, Setagaya-Ku · Setagaya-Ku · tabashi City · Takamatsu · Takatsuki · Tatebayashi · Memory clinic Toride, Toride-shi · Local Institution - 1-13H98LIT, Toride-shi · Tsu · Yokohama · Yokohama City University Hospital, Yokohama · Yokohama City Minato Red Cross Hospital, Yokohama · Yoshinogawa
Registry updated 2026-10-16
NCT06937229
A Study to Evaluate the Long-term Efficacy and Safety of KarXT + KarX-EC for Agitation in Alzheimer's Disease (ADAGIO-3)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Nippon Medical School Hospital, Bunkyo-ku · Kuramitsu Hospital, Fukuoka · Hatano Kousei Hospital, Hadano · National Hospital Organization Hizen Psychiatric Center, Kanzaki-Gun Yoshinogari-Cho · Rainbow and Sea Hospital, Karatsu-shi · Kawasaki · Okayama City General Medical Center Okayama City Hospital, Okayama · Asakayama Hospital, Sakai · Jichi Medical University Hospital, Shimotsuke-shi, Tochigi
Registry updated 2026-10-16
NCT06976203
A Study to Evaluate the Efficacy and Safety of KarXT + KarX-EC for Cognitive Impairment in Alzheimer's Disease (MINDSET 2)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Hirakata · Imon Yukari Neurology Clinic, Hiroshima · Ina Central Hospital, Ina · Inage Neurology and Memory Clinic, Inage · Kamakura · National Hospital Organization Niigata Hospital, Kashiwazaki · Nippon Medical School Musashi Kosugi Hospital, Kawasaki · Kokankai Kokan Clinic, Kawasaki · Kagawa University Hospital, Kita-gun · KATAYAMA medical Clinic, Kurashiki · Kyoto · Matsudo · Tominaga Clinic, Osaka · Wako Hospital, Wako · Wako · National Hospital Organization Hizen Psychiatric Center, Yoshinogari-cho, Kanzaki-gun
Registry updated 2026-10-08
NCT07843459
A Study of LY4560736 in Healthy Participants and Participants With Alzheimer's Disease (AD)
Trial Treatment · Phase 1 · Eli Lilly and Company
The University of Tokyo Hospital, Bunkyō City · National Center for Geriatrics and Gerontology, Ōbu
Registry updated 2026-10-08
NCT00869817
Dominantly Inherited Alzheimer Network (DIAN)
Research · Washington University School of Medicine
Niigata University, Niigata · Osaka City University, Osaka · Tokyo University, Tokyo
Registry updated 2026-10-05
NCT06803823
A Study of ONO-2020 in Patients With Agitation Associated With Alzheimer's Disease Dementia
Trial Treatment · Phase 2 · Ono Pharmaceutical Co., Ltd.
Hotei Hospital, Aichi · Medical Corporation Keishinkai Kyowa Hospital, Akita · Akita Prefectural Center For Rehabilitation and Psychiatric Medicine, Akita · Aiseikai General Incorporated Foundation, Hirosaki Aiseikai Hospital, Aomori · Seinan Hospital, Aomori · Matsubara Hospital, Fukui · Fukui Hospital, Fukui · Aburayama Hospital, Fukuoka · Kuramitsu Hospital, Fukuoka · Kishikai Kishi Hospital, Gunma · Hayakawa Clinic, Hiroshima · Nakamura Hospital, Hiroshima · Koseikai Cocoro Hospital Kusatsu, Hiroshima · Keiseikai Hospital, Hokkaido · NHO Obihiro National Hospital, Hokkaido · Airanomori Hospital, Kagoshima · Ishiki Hospital, Kagoshima · Sansyu Hospital, Kagoshima · Taniyama Hospital, Kagoshima · Fujisawahospital, Kanagawa · Hatano Kousei Hospital, Kanagawa · Showa Medical University Northern Yokohama Hospital, Kanagawa · Ichiyo Mental Hospital, Kochi · Hosogi Hospital, Kochi · Maizuru Medical Center, Kyoto · Nishiyama Hospital, Kyoto · Iryohojin Shadan Shoshinkai Morinohosupitaru・Aoba, Miyagi · Jizenkai Ando Hospital, Nagano · JA-Nagano North Alps Medical Center Azumi Hospital, Nagano · Nara Medical University Hospital, Nara · Osaka Institute of Clinical Psychiatry Shin-Abuyama Hospital, Osaka · Nagaokai Neyagawa Sanatorium, Osaka · Osaka Psychiatric Medical Center, Osaka · Hizen Psychiatric Center, Saga · Rainbow & Sea Hospital, Saga · Saitama Konan Hospital, Saitama · Nishigahara Hospital, Tokyo · Asuka Hospital, Tokyo · Sanyokai Sanyo Hospital, Yamagata
Registry updated 2026-09-25
NCT07142954
Epidemiology and Biomarker Study in Alzheimer's Disease
Trial Treatment · Phase 3 · Eli Lilly and Company
The University of Tokyo Hospital, Bunkyō City · Souseikai Sumida Hospital, Tokyo · Higashi Shinjuku Clinic, Tokyo
Registry updated 2026-07-07
NCT06947941
A Study to Evaluate Safety and Efficacy of KarXT + KarX-EC as a Treatment for Psychosis Associated With Alzheimer's Disease (ADEPT-5)
Trial Treatment · Phase 3 · Bristol-Myers Squibb
Nankoku-shi · Osaka · Suita
Registry updated 2026-06-30
NCT06657768
A Study of LY4006895 in Healthy Participants With Early Symptomatic Alzheimer's Disease (AD)
Trial Treatment · Phase 1 · Eli Lilly and Company
The University of Tokyo Hospital, Bunkyō City · National Center for Geriatrics and Gerontology, Ōbu
Registry updated 2026-06-04
NCT06322667
A Post Marketing Study in Participants With Early Alzheimer's Disease Treated With Lecanemab
Research · Eisai Co., Ltd.
Hiroshima · Kyoto · Tokyo
Registry updated 2026-01-23

All Alzheimer disease trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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