Anxiety disorders (generalised anxiety) trials in United States

In United States 104 Also abroad 254

104 trials · From ClinicalTrials.gov, checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Study of Neuro-Cognitive Correlates of Pediatric Anxiety Disorders
Where
Bethesda, College Park
Age
8 years to 65 years
People
3,500
Run by
National Institute of Mental Health (NIMH)
See details and how to joinNCT00018057
No phaseTaking people
Development of Magnetic Resonance Imaging Techniques for Studying Mood and Anxiety Disorders
Where
Bethesda
Age
18 years to 65 years
People
390
Run by
National Institute of Mental Health (NIMH)
See details and how to joinNCT00397111
Phase 3Taking people
A Trial of the Efficacy and Safety of a Fixed Dose of SEP-363856 in Adults With Generalized Anxiety Disorder
Where
Austin, Cherry Hill, Everett, Fairfax, Hallandale, Houston, Jamaica, Los Angeles, Memphis, Methuen, New York, Oklahoma City, Orlando, Philadelphia, Phoenix, Portland, Redlands, Sherman Oaks, The Bronx, Valley Village, Watertown
Age
18 years and over
People
384
Run by
Otsuka Pharmaceutical Development & Commercialization, Inc.
See details and how to joinNCT07767903 · EU 2026-526034-10-00
Phase 3Taking people
A Trial of the Safety and Tolerability of SEP-363856 in Adults With Generalized Anxiety Disorder
Where
Jacksonville, Jamaica, New York, Orlando
Age
18 years and over
People
1,120
Run by
Otsuka Pharmaceutical Development & Commercialization, Inc.
See details and how to joinNCT07786454 · EU 2026-526032-40-00
No phaseEnrolling by invitation
Pediatric Behavioral Health Integrated Care: Indiana Statewide Strategic Plan to Address the Growing Mental Health Crisis
Where
Indianapolis
Age
5 years and over
People
575
Run by
Indiana University
See details and how to joinNCT07216638
Phase 2Taking people
Gaze-Contingent Music Therapy Augmentation of CBT for Pediatric Anxiety
Where
Bethesda
Age
8 years to 17 years
People
150
Run by
National Institute of Mental Health (NIMH)
See details and how to joinNCT06595953
No phaseTaking people
LIFU for Chronic Pain and Generalized Anxiety Disorder
Where
Roanoke
Age
18 years to 65 years
People
10
Run by
Virginia Polytechnic Institute and State University
See details and how to joinNCT07686354
No phaseTaking people
Modulating Anxious Coping
Where
Charleston
Age
18 years to 65 years
People
80
Run by
Medical University of South Carolina
See details and how to joinNCT04824105
No phaseTaking people
DINO RCT - Treating Anxiety in Children With Autism
Where
Baltimore
Age
4 years to 6 years
People
70
Run by
Hugo W. Moser Research Institute at Kennedy Krieger, Inc.
See details and how to joinNCT06066983
No phaseTaking people
Parent-Based Treatment for Adolescent Anxiety
Where
New Haven
Age
14 years to 17 years
People
108
Run by
Yale University
See details and how to joinNCT07219992
No phaseNot yet taking people in United States
Parent-Based Intervention for Childhood Avoidant/Restrictive Food Intake Disorder (ARFID)
Where
New Haven
Age
6 years to 12 years
People
110
Run by
Yale University
See details and how to joinNCT07916974
Phase 2Taking people
Study of ITI-1284 as an Adjunctive Treatment in Patients With Generalized Anxiety Disorder
Where
Allentown, Ann Arbor, Atlanta, Austin, Bellevue, Brooklyn, Glendale, Imperial, Lemon Grove, Media, Miami, Miami Springs, North Canton, Oceanside, Oklahoma City, Orange, Plano, Redlands, Tampa, Toms River
Age
18 years and over
People
705 worldwide
Run by
Intra-Cellular Therapies, Inc.
See details and how to joinNCT06480383 · EU 2024-513302-56-00
Phase 2Taking people
Study of ITI-1284 as Monotherapy Treatment in Patients With Generalized Anxiety Disorder
Where
Bellevue, Birmingham, Brooklyn, Buffalo, Columbus, Culver City, Dallas, Decatur, Encino, Farmington, Flowood, Gainesville, Little Rock, Los Angeles, Media, Miami, Norman, Oceanside, Rogers, Sherman Oaks, Staten Island, Tampa, Upland, Walnut Creek
Age
18 years and over
People
570 worldwide
Run by
Intra-Cellular Therapies, Inc.
See details and how to joinNCT06701903 · EU 2024-516684-82-00
Phase 3Taking people
A Study to Asses Safety and Tolerability of ITI-1284 Given Alone or as an Additional Treatment in Participants With Generalized Anxiety Disorder (GAD)
Where
Brooklyn, Los Angeles, Miami
Age
18 years and over
People
900
Run by
Intra-Cellular Therapies, Inc.
See details and how to joinNCT07807865 · EU 2026-527316-16-00
Phase 3Taking people
A Study of JNJ-99245354 (ITI-1284) as an Adjunctive Treatment in Participants With Generalized Anxiety Disorder (GAD) Who Have an Inadequate Response to GAD Treatment
Where
Miami, New York, Springfield, Temecula
Age
18 years and over
People
705
Run by
Intra-Cellular Therapies, Inc.
See details and how to joinNCT07856420 · EU 2026-527319-40-00
No phaseTaking people
Modulating Escape Using Focused Ultrasound
Where
Charleston
Age
18 years to 65 years
People
40
Run by
Medical University of South Carolina
See details and how to joinNCT06273904
No phaseTaking people
Virtual Reality Intervention to Improve Psychological Symptom Burden for Cancer Patients Undergoing Treatment
Where
Jacksonville
Age
18 years to 90 years
People
24
Run by
Mayo Clinic
See details and how to joinNCT07221409
Phase 3Taking people
A Trial of the Efficacy and Safety of Fixed Doses of SEP-363856 in Adults With Generalized Anxiety Disorder
Where
Boston, Dallas, DeSoto, Encino, Gainesville, Independence, Jacksonville, Las Vegas, Maitland, New Orleans, New York, Oklahoma City, Sherman Oaks, Tucson, Warrenville, Washington D.C.
Age
18 years and over
People
576
Run by
Otsuka Pharmaceutical Development & Commercialization, Inc.
See details and how to joinNCT07759128 · EU 2026-526033-25-00
No phaseTaking people
Neural Mechanisms of Real-world Emotions and Internalizing
Where
Coral Gables
Age
18 years to 35 years
People
144
Run by
University of Miami
See details and how to joinNCT07891624
Phase 3Taking people
Cannabidiol-Assisted Learning for Managing Generalized Anxiety Disorder
Where
Detroit
Age
18 years to 45 years
People
90
Run by
Wayne State University
See details and how to joinNCT07123467
No phaseNot yet taking people in United States
Two Sessions of Coach-Delivered Core Transformation for Distress and Well-Being
Where
Boulder
Age
18 years and over
People
480
Run by
Andreas NLP (Legal Entity - Real People Press)
See details and how to joinNCT07879196
No phaseTaking people
Family Spirit Strengths
Where
Chinle, Pokagon, Shiprock
Age
14 years and over
People
188
Run by
Johns Hopkins Bloomberg School of Public Health
See details and how to joinNCT05836090
No phaseNot yet taking people in United States
An Interrupted Time-Series Pilot Trial of LGBTQ-Affirming Cognitive Processing Therapy for Interpersonal and Developmental Trauma
Where
Birmingham
Age
18 years to 85 years
People
25
Run by
University of Alabama at Birmingham
See details and how to joinNCT07863817
No phaseNot yet taking people in United States
Digital Coach to Support Exposure Therapy Homework for Anxious Youth
Where
Belmont, Boston, Cambridge
Age
12 years to 22 years
People
50
Run by
Massachusetts General Hospital
See details and how to joinNCT07666672
No phaseTaking people
Online Parent Education for Child Anxiety
Where
Boston
Age
18 years and over
People
90
Run by
Massachusetts General Hospital
See details and how to joinNCT07153250