Aortic stenosis trials in Italy

In Italy 35 Also abroad 232

35 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseNot yet taking people in Italy
Validation Of anatomY-specific Aortic Valve Implantation Guided by Software Using EncantoR
Where
Bologna, Castel Volturno, Milan, Roma, San Donato Milanese
Age
18 years and over
People
300 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT07696182
No phaseTaking people
Exercise and Diet Supplements for Older Patients Undergoing TAVI: the IRON-TAVI Trial
Where
Ferrara
Age
75 years and over
People
450
Run by
University Hospital of Ferrara
See details and how to joinNCT07895719
No phaseTaking people
Heart Failure and Aortic Stenosis Transcriptome
Where
Milan, San Donato Milanese
Age
40 years to 75 years
People
500
Run by
IRCCS Policlinico S. Donato
See details and how to joinNCT03268135
No phaseTaking people
VitaFlow LIBERTY Europe
Where
Castel Volturno, Pisa, Potenza
Age
18 years and over
People
222 worldwide
Run by
Shanghai MicroPort CardioFlow Medtech Co., Ltd.
See details and how to joinNCT06535659
No phaseTaking people
Comparison of Allegra vs Sapien Transcatheter Aortic Valves in Valve-In-Valve Indication
Where
Alessandria, Brescia, Perugia
Age
18 years and over
People
104 worldwide
Run by
Fundación EPIC
See details and how to joinNCT06049654
No phaseEnrolling by invitation
ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation
Where
Milan
Age
18 years and over
People
1,500 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT05932615
No phaseEnrolling by invitation
Transfemoral TAVI With or Without Coronary Angiogram in Patients With Severe Aortic Stenosis (PURE TAVI)
Where
Catania, Mestre, Palermo, Pisa, Roma, Siena, Trieste
Age
18 years and over
People
620 worldwide
Run by
Rede Optimus Hospitalar SA
See details and how to joinNCT06898086
No phaseTaking people
TRanscatheter Aortic-Valve Implantation Without On-site Cardiac Surgery
Where
Andria, Arezzo, Bologna, Ferrara, Grosseto, L’Aquila, Mirano, Ravenna, Rimini, Venezia, Verona
People
1,612
Run by
University Hospital of Ferrara
See details and how to joinNCT07604402
No phaseTaking people
LANDMARK Trial: a Randomised Controlled Trial of Myval THV
Where
Bologna, Catania, Milan, Tortona, Turin
Age
18 years and over
People
988 worldwide
Run by
Meril Life Sciences Pvt. Ltd.
See details and how to joinNCT04275726
Phase 4Taking people
Single Antiplatelet Treatment With Ticagrelor or Aspirin After Transcatheter Aortic Valve Implantation
Where
Catania, San Donato Milanese, Verona
Age
18 years and over
People
1,206 worldwide
Run by
Fundacin Biomedica Galicia Sur
See details and how to joinNCT05283356 · EU 2023-509290-22-00
No phaseTaking people
International Multicenter Study of the Navitor/Navitor Vision Transcatheter Aortic Valve Platform
Where
San Donato Milanese
Age
18 years and over
People
1,000
Run by
IRCCS Policlinico S. Donato
See details and how to joinNCT07359898
No phaseTaking people
Post-Market Clinical Follow Up Study With Navitor Valve
Where
Brescia, Castel Volturno, Milan, Palermo, Roma, San Donato Milanese, Torino
Age
18 years to 100 years
People
1,000 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT06008080
No phaseTaking people
In-vitro Benchmarking of Currently Available Heart Valve Prostheses for Surgical and Percutaneous Treatment of Aortic Stenosis With Small Annulus, Followed by In-vivo Validation
Where
Bari, San Donato
People
200
Run by
IRCCS Policlinico S. Donato
See details and how to joinNCT06859255
Phase 2Taking people
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Where
Ancona, Bergamo, Brescia, Caserta, Ferrara, Milan, Padova, Pordenone, Pozzilli
Age
50 years to 80 years
People
502 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05646381 · EU 2022-502135-19-00
No phaseTaking people
Derivation and Validation of the Aortic Valve Echocardiographic Calcium Score to Confirm Severe Aortic Stenosis: the Echo-AVCS Study
Where
Bologna, Milan, Roma
Age
18 years and over
People
250
Run by
Azienda Ospedaliera "Sant'Andrea"
See details and how to joinNCT07620925
No phaseTaking people
Impact of Trans-catheter Aortic Valve Implantation on Renal Function
Where
Roma
Age
18 years and over
People
1,000
Run by
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
See details and how to joinNCT07626710
No phaseTaking people
A Registry to Assess the Efficacy and Safety of Transcatheter Treatment for Aortic Valve Disease at the IRCCS Policlinico San Matteo Foundation in Pavia (Italy).
Where
Pavia
Age
18 years and over
People
500
Run by
Fondazione IRCCS Policlinico San Matteo di Pavia
See details and how to joinNCT07596394
Phase 3Taking people
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
Where
Milan, Roma, Torino, Verona
Age
6 years to 11 years
People
60 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06597019
No phaseTaking people
Surgical vs Transcatheter Aortic Valve Replacement in YOUNG Patients
Where
Mercogliano, Milan, Parma, Roma, San Donato Milanese
Age
65 years to 75 years
People
1,180 worldwide
Run by
Ceric Sàrl
See details and how to joinNCT06861361
No phaseTaking people
COronary Re-engageMent aFter randOm NavitoR alignmenT (COMFORT STUDY)
Where
Milan
Age
18 years and over
People
100
Run by
Niguarda Hospital
See details and how to joinNCT05779787
No phaseTaking people
Ischemic And Bleeding Risk Assessment After TAVR
Where
Genova, Milan, Potenza, Roma, Rozzano, San Donato Milanese, Torino
Age
18 years and over
People
2,500 worldwide
Run by
Niguarda Hospital
See details and how to joinNCT06000943
No phaseTaking people
Transcatheter Aortic Valve Replacement in Severe Low Flow, Low Gradient Aortic Stenosis
Where
Salerno
Age
18 years and over
People
1,350
Run by
University of Salerno
See details and how to joinNCT06589063
No phaseTaking people
MiECC Versus Conventional Cardiopulmonary Bypass in Cardiac Surgery (MiECS)
Where
Bari, Palermo
Age
18 years to 85 years
People
1,300 worldwide
Run by
Aristotle University Of Thessaloniki
See details and how to joinNCT05487612
No phaseTaking people
Phenotyping Left Ventricle Failure With Hemodynamic Biomarkers From 4D Flow Magnetic Resonance Imaging
Where
San Donato Milanese
Age
18 years and over
People
190
Run by
IRCCS Policlinico S. Donato
See details and how to joinNCT07455292
No phaseEnrolling by invitation
Demographic and Interpopulation Variations in Evaluation and Results of TAVI
Where
Vicenza
Age
18 years and over
People
800 worldwide
Run by
Poznan University of Medical Sciences
See details and how to joinNCT07258706