Aortic stenosis trials in Netherlands

In Netherlands 20 Also abroad 232

20 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 4Not yet taking people in Netherlands
Iron Infusion in Elderly Patients undergoing Transcatheter Aortic Valve Implantation (IRON TAVI) Trial
Where
Rotterdam
Age
18 years and over
People
378
Run by
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
See details and how to join2023-505095-29-03
No phaseTaking people
SYMmetric Valve fraME Expansion To Reduce hYpoattenuated Leaflet Thickening After Balloon-expandable TAVI: the SYMMETRY Trial
Where
Amsterdam, Breda, Maastricht, Rotterdam
Age
70 years and over
People
422 worldwide
Run by
Erasmus Medical Center
See details and how to joinNCT07872020
No phaseEnrolling by invitation
ENVISION IDE Trial: Safety and Effectiveness of NAVITOR in Transcatheter Aortic Valve Implantation
Where
Groningen
Age
18 years and over
People
1,500 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT05932615
No phaseEnrolling by invitation
Transfemoral TAVI With or Without Coronary Angiogram in Patients With Severe Aortic Stenosis (PURE TAVI)
Where
Amsterdam, Maastricht
Age
18 years and over
People
620 worldwide
Run by
Rede Optimus Hospitalar SA
See details and how to joinNCT06898086
No phaseTaking people
LANDMARK Trial: a Randomised Controlled Trial of Myval THV
Where
Amsterdam, Breda, Groningen, Nieuwegein, Nijmegen, Utrecht, Zwolle
Age
18 years and over
People
988 worldwide
Run by
Meril Life Sciences Pvt. Ltd.
See details and how to joinNCT04275726
Phase 3Taking people
Study to Evaluate Safety, Tolerability and Efficacy of Inclisiran in Children With Homozygous Familial Hypercholesterolemia
Where
Amsterdam
Age
2 years to 11 years
People
9 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06597006
No phaseTaking people
The Early Valve Replacement in Severe ASYmptomatic Aortic Stenosis Study
Where
Leeuwarden, Nijmegen
Age
18 years and over
People
2,104 worldwide
Run by
University of Leicester
See details and how to joinNCT04204915
No phaseTaking people
Post-Market Clinical Follow Up Study With Navitor Valve
Where
Amsterdam, Leiden, Utrecht
Age
18 years to 100 years
People
1,000 worldwide
Run by
Abbott Medical Devices
See details and how to joinNCT06008080
No phaseTaking people
Optimized Expansion of the Implanted Transcatheter Aortic Valve
Where
Amsterdam, Groningen, Leiden, Nieuwegein
Age
18 years and over
People
1,010 worldwide
Run by
Ole De Backer
See details and how to joinNCT07042529
Phase 2Taking people
A Multicenter Trial Assessing the Impact of Lipoprotein(a) Lowering With Pelacarsen (TQJ230) on the Progression of Calcific Aortic Valve Stenosis
Where
Amsterdam, Nieuwegein, Rotterdam
Age
50 years to 80 years
People
502 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05646381 · EU 2022-502135-19-00
No phaseTaking people
The Effect of Subclinical Leaflet Thrombosis and Prosthesis Type on Transcatheter Aortic Valve Degeneration (POPular PET TAVI)
Where
Amsterdam, Nieuwegein
Age
18 years and over
People
180 worldwide
Run by
St. Antonius Hospital
See details and how to joinNCT05758662
Phase 4Taking people
Personalized, CT-guided Antithrombotic Therapy Versus Lifelong Single Antiplatelet Therapy to Reduce Thromboembolic and Bleeding Events in Non-atrial Fibrillation Patients After Transcatheter Aortic Valve Implantation
Where
Amsterdam, Breda, Groningen, Leeuwarden, Leiden, Maastricht, Nieuwegein, Nijmegen
Age
18 years to 110 years
People
2,500 worldwide
Run by
St. Antonius Hospital
See details and how to joinNCT06168370 · EU 2023-504637-42-01
Phase 3Taking people
Study to Evaluate Efficacy and Safety of Inclisiran in Children With Heterozygous Familial Hypercholesterolemia
Where
Amsterdam
Age
6 years to 11 years
People
60 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT06597019
No phaseNot yet taking people in Netherlands
Valvosoft Outcomes Registry for Real-World Evidence
Where
Nijmegen
Age
18 years and over
People
200 worldwide
Run by
Cardiawave SA
See details and how to joinNCT07520591
Phase 4Taking people
Iron Infusion in Patients Undergoing Transcatheter Aortic Valve Implantation
Where
Rotterdam
Age
65 years and over
People
402
Run by
Erasmus Medical Center
See details and how to joinNCT07370688
No phaseTaking people
PROGRESS: Management of Moderate Aortic Stenosis by Clinical Surveillance or TAVR
Where
Amsterdam, Leiden, Rotterdam
Age
65 years and over
People
2,250 worldwide
Run by
Edwards Lifesciences
See details and how to joinNCT04889872
No phaseTaking people
Prospective Registry of Patients Undergoing Cardiac CT With NAEOTOM Alpha PCD-CT Before TAVI Procedure
Where
Maastricht
Age
18 years and over
People
1,000 worldwide
Run by
Semmelweis University
See details and how to joinNCT07016477
Phase 3Taking people
Colchicine and Inflammation in Aortic Stenosis (CHIANTI) trial
Where
Alkmaar, Nijmegen
Age
18 years and over
People
150
Run by
Stichting Radboud universitair medisch centrum
See details and how to join2024-513486-39-00
No phaseTaking people
Future Optimal Research and Care Evaluation - Aortic Stenosis
Where
Nieuwegein
Age
18 years to 110 years
People
800
Run by
St. Antonius Hospital
See details and how to joinNCT06168123
No phaseTaking people
Myval Global Study of Myval™ THV Series Implanted in Patients With Native Severe Aortic Valve Stenosis.
Where
Breda
Age
18 years and over
People
200 worldwide
Run by
Meril Life Sciences Pvt. Ltd.
See details and how to joinNCT04703699