Asthma trials in South Africa

In South Africa 13 Also abroad 500

13 trials · From ClinicalTrials.gov, checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseNot yet taking people in South Africa
Pulmonary Rehabilitation in African Countries
Where
Johannesburg
Age
18 years and over
People
150 worldwide
Run by
University of Edinburgh
See details and how to joinNCT07602673
Phase 2Taking people
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate-To-Severe Asthma
Where
Durban, Johannesberg, Johannesburg
Age
18 years to 75 years
People
252 worldwide
Run by
Pfizer
See details and how to joinNCT06977581 · EU 2024-517866-40-00
Phase 2Taking people
Dose Range Finding Study to Assess Efficacy and Safety of Tozorakimab in Adults With Uncontrolled Asthma on Medium-to-High Dose Inhaled Corticosteroids
Where
Bellville, Benoni, Brackenfell, Cape Town, Durban, eMkhomazi, Somerset West
Age
18 years to 75 years
People
540 worldwide
Run by
AstraZeneca
See details and how to joinNCT06932263 · EU 2024-519116-14-00
Phase 3Taking people
A Study to Investigate GB-0895 Adjunctive Therapy in Adults and Adolescents With Severe Uncontrolled Asthma (SOLAIRIA-1)
Where
Cape Town, Durban, Johannesburg, KwaDukuza, Sydenham, Welkom
Age
12 years to 80 years
People
786 worldwide
Run by
Generate Biomedicines
See details and how to joinNCT07276724 · EU 2025-521950-41-00
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of QMF149 (Indacaterol Acetate/Mometasone Furoate) Versus Budesonide in Children From 6 to Less Than 12 Years of Age With Asthma
Where
Bloemfontein, Cape Town, Centurion, George, Pretoria, Raslouw Centurion
Age
6 years to 11 years
People
200 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05562466 · EU 2022-501899-26-00
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of QVM149 (Indacaterol Acetate / Glycopyrronium Bromide / Mometasone Furoate) Versus Salmeterol Xinafoate/Fluticasone Propionate in Children From 12 Years to Less Than 18 Years of Age With Asthma.
Where
Cape Town, East London, Germiston, Krugersdorp, Lenasia, Paarl
Age
12 years to 17 years
People
188 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05776927
Phase 3Taking people
A Study to Investigate the Efficacy and Safety of Tezepelumab Compared With Placebo in Children 5 to < 12 Years Old With Severe Asthma
Where
Bellville, Cape Town, Durban, Middelburg, Thabazimbi, Vereeniging, Welkom
Age
5 years to 11 years
People
231 worldwide
Run by
AstraZeneca
See details and how to joinNCT06023589
Phase 3Taking people
Evaluating the Efficacy and Safety of PT027 Compared With PT007 Administered As Needed in Participants 12 to < 18 Years of Age With Asthma
Where
Durban, Krugersdorp, Middelburg, Panorama, Somerset West, Welkom
Age
12 years to 17 years
People
440 worldwide
Run by
AstraZeneca
See details and how to joinNCT06307665
Phase 4Not yet taking people in South Africa
Prevent Wheeze Trial
Where
Johannesburg
Age
3 months to 24 months
People
486 worldwide
Run by
Norwegian University of Science and Technology
See details and how to joinNCT07858773
Phase 2Enrolling by invitation
Long-term Safety and Efficacy Evaluation of Lunsekimig (SAR443765) in Adult Participants With Asthma
Where
Benoni, Cape Town, Durban, Pretoria
Age
18 years and over
People
900 worldwide
Run by
Sanofi
See details and how to joinNCT06609239 · EU 2025-522896-27-00
Phase 2Taking people
Pharmacokinetics, Pharmacodynamics, Safety and Tolerability of Glycopyrronium (Bromide) in Children (6 to Less Than 12 Years) With Asthma
Where
Cape Town, George
Age
6 years to 11 years
People
42 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05222529 · EU 2024-511382-11-00
Phase 2Taking people
Therapeutic Equivalence of CHF5993 pMDI 100/6/12.5 µg HFA-152a in Subjects With Mild to Moderate Asthma
Where
Bellville, Benoni, Bloemfontein, Cape Town, Chatsworth, Durban, George, KwaZulu, Middelburg, Pretoria, Welkom
Age
18 years to 75 years
People
780 worldwide
Run by
Chiesi Farmaceutici S.p.A.
See details and how to joinNCT07301736 · EU 2025-521456-35-00
Phase 3Taking people
Anti-Inflammatory Reliever South Africa
Where
Mtubatuba
Age
6 years to 18 years
People
1,038
Run by
University of KwaZulu
See details and how to joinNCT06429475