Bipolar disorder trials in Italy

In Italy 9 Also abroad 235

9 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-2)
Where
Ancona, Genova, Milan, Pisa, Siena
Age
18 years to 65 years
People
274 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06951711
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of Adjunctive KarXT for the Treatment of Mania, With or Without Mixed Features, in Participants With Bipolar-I Disorder Taking Lithium, Valproate, or Lamotrigine
Where
Ancona, Genova, Milan, Pisa, Siena
Age
18 years to 65 years
People
424 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07140913
Phase 3Taking people
A Study to Assess the Long-term Safety of KarXT for the Treatment of Manic Episodes in Bipolar-I Disorder (BALSAM-3)
Where
Ancona, Genoa, Milan, Pisa, Siena
Age
18 years to 65 years
People
450 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT06929273 · EU 2024-520259-26-00
No phaseNot yet taking people in Italy
Chemokine Receptors on CD8+ T Cells in Patients With Bipolar Disorder
Where
Catania
Age
25 years to 35 years
People
172
Run by
University of Catania
See details and how to joinNCT07785167
No phaseNot yet taking people in Italy
Testing a New Gold Nanoparticle-Based Lithium Delivery Method for Bipolar Disorder in Laboratory Models
Where
Roma
Age
18 years to 65 years
People
20
Run by
Fondazione Policlinico Universitario Agostino Gemelli IRCCS
See details and how to joinNCT07732933
No phaseNot yet taking people in Italy
Non-Coding RNAs Gene Expression in Psychiatric Disorders
Where
Catania, Enna, Messina, Palermo
Age
18 years to 55 years
People
384
Run by
Carmen Concerto
See details and how to joinNCT07649993
Phase 3Taking people
The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.
Where
Brescia, Cagliari, Naples, Turin
Age
18 years and over
People
418 worldwide
Run by
Dr. Inge Winter
See details and how to joinNCT05973786 · EU 2023-506605-19-00
Phase 4Not yet taking people in Italy
EFFECTIVENESS OF SUPPLEMENTATION WITH VITAMIN D IN PATIENTS WITH DEPRESSIVE DISORDER OR BIPOLAR DISORDER: A RANDOMIZED CONTROLLED CLINICAL TRIAL
Where
Siena
Age
18 years and over
People
150
Run by
Azienda Ospedaliera Universitaria Senese
See details and how to join2025-520778-20-00 · EU 2025-520778-20-00
No phaseTaking people
A Study of the Behavioral Variant of Frontotemporal Dementia and Bipolar Disorder: a Neuroimaging and Epigenetics Integrated Approach
Where
Milan
Age
18 years and over
People
210
Run by
Fondazione IRCCS Ca' Granda, Ospedale Maggiore Policlinico
See details and how to joinNCT06706687