Bladder cancer trials in Canada

In Canada 41 Also abroad 626

41 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 1/2Taking people
A Clinical Study of MK-3120 in People With Bladder Cancer (MK-3120-003)
Where
Québec
Age
18 years and over
People
45 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07222488 · EU 2025-520467-40-00
Phase 3Taking people
A Clinical Trial of Sacituzumab Tirumotecan (Sac-TMT, MK-2870) to Treat Urothelial Cancer (MK-2870-031)
Where
Oshawa, Québec, Toronto
Age
18 years and over
People
590 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT07419295 · EU 2024-520014-22-00
Phase 2Taking people
Testing the Addition of the Immunotherapy Drug, Pembrolizumab, to Radiation Therapy Compared to the Usual Chemotherapy Treatment During Radiation Therapy for Bladder Cancer, PARRC Trial
Where
Montreal, Québec
Age
18 years and over
People
160 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT06770582
Phase 2/3Taking people
Testing the Role of DNA Released From Tumor Cells Into the Blood in Guiding the Use of Immunotherapy After Surgical Removal of the Bladder, Kidney, Ureter, and Urethra for Urothelial Cancer Treatment, MODERN Study
Where
Calgary, Edmonton, Kitchener, London, Ottawa, Regina, Saskatoon, Toronto, Vancouver
Age
18 years and over
People
992 worldwide
Run by
National Cancer Institute (NCI)
See details and how to joinNCT05987241
Phase 1Taking people
A Study to Learn About the Study Medicine Called PF-08046876 in People With Advanced Solid Tumors
Where
Montreal, Toronto
Age
18 years and over
People
540 worldwide
Run by
Pfizer
See details and how to joinNCT07090499 · EU 2025-521729-33-00
Phase 1Taking people
FORAGER-1: A Study of Vepugratinib (LY3866288; LOXO-435) in Participants With Cancer With a Change in a Gene Called FGFR3
Where
Toronto, Vancouver
Age
18 years and over
People
677 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT05614739 · EU 2022-502755-59-00
Phase 2Taking people
A Study to Learn More About How Well Treatment With Sevabertinib (BAY 2927088) Tablets Works and How Safe it is in Participants Who Have a Solid Tumor With Mutations of the Human Epidermal Growth Factor Receptor 2 (HER2)
Where
Halifax, Montreal, Toronto
Age
18 years and over
People
111 worldwide
Run by
Bayer
See details and how to joinNCT06760819 · EU 2024-517419-62-00
Phase 1Taking people
Study of [177Lu]Lu-DWJ155 and [68Ga]Ga-DWJ155 in Patients With Solid Tumors
Where
Montreal
Age
18 years and over
People
156 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07660055
Phase 2Taking people
A Study to Find Out if Enfortumab Vedotin Given With Pembrolizumab Helps People With Muscle-invasive Bladder Cancer Keep Their Bladder
Where
Toronto
Age
18 years and over
People
240 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT07475806
Phase 3Taking people
Trial of Nadofaragene Firadenovec vs. Observation in Participants With Intermediate Risk Non-Muscle Invasive Bladder Cancer
Where
Burlington, Calgary, Hamilton, Toronto
Age
18 years and over
People
454 worldwide
Run by
Ferring Pharmaceuticals
See details and how to joinNCT06510374 · EU 2024-512029-10-00
Phase 3Taking people
A Trial to Evaluate Intravesical Nadofaragene Firadenovec Alone or in Combination With Chemotherapy or Immunotherapy in Participants With High-grade BCG Unresponsive Non-muscle Invasive Bladder Cancer
Where
Calgary, Hamilton, Montreal, Toronto
Age
18 years and over
People
250 worldwide
Run by
Ferring Pharmaceuticals
See details and how to joinNCT06545955 · EU 2024-512177-27-01
No phaseTaking people
Exploration of Novel AI-enabled Blue Light Enhanced Cystoscopy
Where
Vancouver
Age
18 years and over
People
500 worldwide
Run by
Photocure
See details and how to joinNCT07144319
Phase 3Taking people
Enfortumab Vedotin in Combination With Pembrolizumab vs. Concurrent Chemoradiotherapy (cCRT) in People With Muscle Invasive Bladder Cancer (EV-309)
Where
Chicoutimi, Montreal
Age
18 years and over
People
390 worldwide
Run by
Astellas Pharma Global Development, Inc.
See details and how to joinNCT07566156 · EU 2026-525612-34-00
Phase 2Taking people
A Phase II Trial of Bicalutamide in Patients Receiving Intravesical BCG for Non-muscle Invasive Bladder Cancer
Where
Lévis, London, Montreal, Québec, Sherbrooke, Toronto
Age
18 years and over
People
160
Run by
CHU de Quebec-Universite Laval
See details and how to joinNCT05327647
Phase 2Taking people
A Study of HER3-DXd in Subjects With Locally Advanced or Metastatic Solid Tumors
Where
Edmonton, Toronto, Vancouver
Age
18 years and over
People
740 worldwide
Run by
Daiichi Sankyo
See details and how to joinNCT06172478 · EU 2023-507641-29-00
Phase 3Taking people
Testing Shorter Duration Radiation Therapy Versus the Usual Radiation Therapy in Patients Receiving the Usual Chemotherapy Treatment for Bladder Cancer, ARCHER Study
Where
Montreal
Age
18 years and over
People
486 worldwide
Run by
NRG Oncology
See details and how to joinNCT07097142
Phase 2Taking people
Perioperative Durvalumab With Neoadjuvant ddMVAC in Patients With Muscle-Invasive Bladder Cancer (NIAGARA-2)
Where
Hamilton, London, Montreal, Ottawa, Québec, Sherbrooke
Age
18 years and over
People
150 worldwide
Run by
AstraZeneca
See details and how to joinNCT06960577 · EU 2024-519246-75-01
Phase 3Taking people
A Study of Vepugratinib (LY3866288) in Participants With Cancer in the Urinary Tract
Where
Calgary, Hamilton, Québec, Vancouver
Age
18 years and over
People
450 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07218380 · EU 2025-522855-25-00
Phase 3Taking people
Neoadjuvant Upper Tract Invasive Cancer Trial (NAUTICAL)
Where
Ottawa, Toronto
Age
18 years and over
People
14
Run by
University Health Network, Toronto
See details and how to joinNCT04574960
Phase 2Taking people
A Clinical Study of Intismeran Autogene (V940) and BCG in People With Bladder Cancer (V940-011/INTerpath-011)
Where
Moncton, Sherbrooke
Age
18 years and over
People
308 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06833073 · EU 2024-517335-46-00
Phase 3Not yet taking people in Canada
The Impact of Time-of-day Administration of EV/P on Objective Response Rate in Adults With Advanced Bladder Cancer
Where
Abbotsford British Columbia, Kelowna, Surrey, Vancouver, Victoria
Age
18 years and over
People
224
Run by
Guliz Ozgun
See details and how to joinNCT07346053
Phase 2Taking people
Phase 2 Study to Evaluate Safety and Efficacy of Cretostimogene Grenadenorepvec in High-Risk NMIBC
Where
Halifax
Age
18 years and over
People
325 worldwide
Run by
CG Oncology, Inc.
See details and how to joinNCT06567743
Phase 2Taking people
Safety and Efficacy Study of Intravesical Instillation of TARA-002 in Adults With High-grade Non-muscle Invasive Bladder Cancer
Where
Abbotsford British Columbia, Brampton, Montreal, Toronto
Age
18 years and over
People
131 worldwide
Run by
Protara Therapeutics
See details and how to joinNCT05951179
Phase 1/2Taking people
A Study of BMS-986340 as Monotherapy and as Combination Therapy in Participants With Advanced Solid Tumors
Where
Edmonton, Hamilton, Montreal, Ottawa, Toronto, Vancouver
Age
18 years and over
People
1,109 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT04895709
Phase 1/2Taking people
A Study of a Selective T Cell Receptor (TCR) Targeting, Bifunctional Antibody-fusion Molecule STAR0602 in Participants With Advanced Solid Tumors
Where
Toronto
Age
18 years and over
People
366 worldwide
Run by
Marengo Therapeutics, Inc.
See details and how to joinNCT05592626 · EU 2023-505334-10-01