Childhood cancers trials in Brazil

In Brazil 32 Also abroad 2459

32 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Effectiveness and Safety of Tisagenlecleucel Therapy in Brazilian Patients With B-lymphocyte Malignancies
Where
Curitiba, Minas Gerais, Salvador, São Paulo
Age
0 years to 100 years
People
200
Run by
Novartis Pharmaceuticals
See details and how to joinNCT05541341
Phase 3Taking people
Study of Volrustomig in Women With High Risk Locally Advanced Cervical Cancer (eVOLVE-Cervical)
Where
Barretos, Belo Horizonte, Curitiba, Fortaleza, Goiânia, Ijuí, Natal, Porto Alegre, Porto Velho, Recife, Rio de Janeiro, Salvador, São Paulo, Teresina
Age
15 years and over
People
800 worldwide
Run by
AstraZeneca
See details and how to joinNCT06079671 · EU 2023-504374-38-00
Phase 2Taking people
Study to Determine the Efficacy and Safety of Asciminib in Pediatric Patients With Ph+ CML-CP
Where
Barretos, Rio de Janeiro, São Paulo
Age
1 year to 18 years
People
50 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT07354074
Phase 4Taking people
Asciminib Roll-over Study
Where
Rio de Janeiro, São Paulo
Age
7 years to 100 years
People
347 worldwide
Run by
Novartis Pharmaceuticals
See details and how to joinNCT04877522 · EU 2023-507557-16-00
Phase 2Taking people
Target Validation and Efficacy of Metformin in Patients With Posterior Fossa Group A (PFA) Ependymoma
Where
São Paulo
Age
1 year to 39 years
People
30 worldwide
Run by
University of California, San Francisco
See details and how to joinNCT07226453
Phase 1/2Taking people
A Study to Evaluate Glofitamab Monotherapy and Glofitamab + Chemoimmunotherapy in Pediatric and Young Adult Participants With Relapsed/Refractory Mature B-Cell Non-Hodgkin Lymphoma
Where
Curitiba, São Paulo
Age
6 months to 30 years
People
65 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT05533775
Phase 1/2Taking people
A Phase 1/2 Study of Bleximenib in Participants With Acute Leukemia (cAMeLot-1)
Where
Brasília, Natal, Rio de Janeiro, São Paulo
Age
2 years and over
People
420 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT04811560 · EU 2023-506581-31-00
No phaseTaking people
Adult Acute Lymphoblastic Leukemia Treated With Pediatric Regimen in Brazil
Where
São Paulo
Age
16 years to 50 years
People
180
Run by
Instituto do Cancer do Estado de São Paulo
See details and how to joinNCT05959720
Phase 2Taking people
Entrectinib as a Single Agent in Upfront Therapy for Children <3 Years of Age With NTRK1/2/3 or ROS1-FUSED CNS Tumors
Where
Barretos, São Paulo
Age
Up to 3 years
People
52 worldwide
Run by
St. Jude Children's Research Hospital
See details and how to joinNCT06528691
Phase 1/2Taking people
Substudy 01A: Zilovertamab Vedotin in Pediatric and Young Adult Participants With Hematologic Malignancies or Solid Tumors (MK-9999-01A/LIGHTBEAM-U01)
Where
Barretos, Curitiba, Porto Alegre, São José do Rio Preto
Age
6 months to 25 years
People
90 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06395103 · EU 2023-507178-41-00
No phaseTaking people
GYNGHER - HER2 Expression in Gynecological Malignancies: a Brazilian Cohort
Where
São Paulo
People
350
Run by
AstraZeneca
See details and how to joinNCT07101081
Phase 3Taking people
Study of Revumenib in Combination With Intensive Chemotherapy in Newly Diagnosed Acute Myeloid Leukemia (AML) With a NPM1 Mutation
Where
Barretos, Fortaleza, Jaú, Porto Alegre, São Paulo
Age
12 years and over
People
468 worldwide
Run by
Syndax Pharmaceuticals
See details and how to joinNCT07211958 · EU 2025-522279-27-00
Phase 1/2Taking people
AZD0486 as Monotherapy in B-cell Acute Lymphoblastic Leukaemia
Where
Porto Alegre, São Paulo
Age
12 years and over
People
255 worldwide
Run by
AstraZeneca
See details and how to joinNCT06137118 · EU 2023-505840-20-00
Phase 1/2Taking people
AZD3470 as Monotherapy or in Combination With Anticancer Agent(s) in Participants With Haematologic Malignancies.
Where
São Paulo
Age
12 years and over
People
161 worldwide
Run by
AstraZeneca
See details and how to joinNCT06137144 · EU 2023-506747-42-00
Phase 1/2Taking people
A Study of Patritumab Deruxtecan in Pediatric Participants With Relapsed or Refractory Solid Tumors (MK-9999-01C/LIGHTBEAM-U01)
Where
Barretos, Porto Alegre, São José do Rio Preto
Age
1 month to 17 years
People
50 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT06941272 · EU 2024-518771-66-00
Phase 2Taking people
A Study of Propranolol to Treat Kaposi Sarcoma
Where
Rio de Janeiro, Salvador
People
25 worldwide
Run by
AIDS Malignancy Consortium
See details and how to joinNCT05797662
Phase 2Taking people
Naxitamab Added to Induction for Newly Diagnosed High-Risk Neuroblastoma
Where
São Paulo
Age
12 months to 21 years
People
93 worldwide
Run by
Giselle Sholler
See details and how to joinNCT05489887 · EU 2025-524140-35-00
No phaseTaking people
International Rare Brain Tumor Registry
Where
São Paulo
Age
Up to 45 years
People
5,800 worldwide
Run by
Children's National Research Institute
See details and how to joinNCT05697874
No phaseTaking people
Screening Tool Artificial Intelligence-based for Predicting the Genetic Risk of BREAST Cancer
Where
Golania, Porto Alegre
People
800
Run by
AstraZeneca
See details and how to joinNCT07070128
Phase 1/2Taking people
A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
Where
São Paulo
Age
6 months to 17 years
People
370 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT02332668 · EU 2022-501257-36-00
No phaseTaking people
DeniLA: Comprehensive Demographics and Clinical Profile of NSCLC Patients: Analyzing Guideline-Concordant Care in First-line Treatment Patterns
Where
Recife, Rio de Janeiro, Salvador, São Paulo
People
200
Run by
AstraZeneca
See details and how to joinNCT07109154
Phase 3Taking people
ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)
Where
São Paulo
People
510 worldwide
Run by
Jazz Pharmaceuticals
See details and how to joinNCT05580562 · EU 2022-502051-56-00
No phaseTaking people
Outcomes of Low-Risk Endometrial Cancer With Isolated Tumor Cells in the Sentinel Lymph Nodes: A Prospective, Multicenter, Single-Arm Observational Study
Where
São Paulo
People
212 worldwide
Run by
Mayo Clinic
See details and how to joinNCT06689956
No phaseTaking people
ID Of Prognostic Factors In Mycosis Fungoides/Sezary Syndrome
Where
São Paulo
People
2,000 worldwide
Run by
Stanford University
See details and how to joinNCT02848274
Phase 1Taking people
Clinical Trial Using CAR- T Cells for Treatment of Patients With Refractory or Relapsed CD19-positive B Lymphoid Malignancies
Where
São Paulo
Age
2 years to 70 years
People
30
Run by
Nelson Hamerschlak
See details and how to joinNCT05705570