Childhood cancers trials in Germany

In Germany 143 Also abroad 2481

143 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 13 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Targeted Pediatric High-Grade Glioma Therapy
Where
Heidelberg
Age
12 months to 39 years
People
350 worldwide
Run by
Nationwide Children's Hospital
See details and how to joinNCT05839379
Phase 3Taking people
SIOP RANDOMET 2017
Where
Aachen, Augsburg, Berlin, Bielefeld, Bonn, Braunschweig, Bremen, Dortmund, Dresden, Duesseldorf, Erfurt, Erlangen, Essen, Frankfurt Am Main, Freiburg im Breisgau, Giessen, Göttingen, Greifswald, Halle Saale, Hamburg, Hannover, Heidelberg, Heilbronn, Homburg, Jena, Karlsruhe, Kassel, Kiel, Köln, Leipzig, Lübeck, Mainz, Mannheim, München, Münster, Nürnberg, Oldenburg, Regensburg, Rostock, Sankt Augustin, Stuttgart, Tübingen, Ulm, Würzburg
Age
Up to 17 years
People
409 worldwide
Run by
GPOH gGmbH
See details and how to join2023-508926-91-00
Phase 1/2Taking people
Phase I/II combination umbrella trial in progressive/relapsed/refractory pediatric low-grade glioma (pLGG) (EPILOGUE)
Where
Augsburg, Berlin, Essen, Hamburg, Heidelberg
Age
Up to 64 years
People
34 worldwide
Run by
Universitaetsklinikum Heidelberg AöR
See details and how to join2024-516896-34-00
Phase 3Taking people
SIOP-HRMB: An international prospective trial on clinically high-risk medulloblastoma (HR-MB) in patients older than 3 years.
Where
Aachen, Augsburg, Berlin, Bielefeld, Bonn, Bremen, Brunswick, Cologne, Cottbus, Dortmund, Dresden, Duisburg, Düsseldorf, Erfurt, Erlangen, Essen, Frankfurt Am Main, Freiburg im Breisgau, Giessen, Goettingen, Greifswald, Halle (Saale), Hamburg, Hanover, Heidelberg, Herdecke, Homburg, Jena, Karlsruhe, Kassel, Kiel, Koblenz, Krefeld, Leipzig, Luebeck, Magdeburg, Mainz, Mannheim, Minden, Muenster, München, Munich, Regensburg, Rostock, Sankt Augustin, Schwerin, Stuttgart, Tuebingen, Ulm, Wuerzburg
Age
Up to 64 years
People
311 worldwide
Run by
The University Of Birmingham
See details and how to join2024-510578-25-00
Phase 2/3Taking people
Allogeneic Stem Cell Transplantation for Children and Adolescents With Acute Lymphoblastic Leukaemia
Where
Aachen, Berlin, Bonn, Duesseldorf, Erlangen, Essen, Frankfurt Am Main, Freiburg im Breisgau, Giessen, Greifswald, Halle (Saale), Hamburg, Hanover, Heidelberg, Jena, Kiel, Leipzig, Muenster, Munich, Regensburg, Tuebingen, Ulm, Wuerzburg
Age
1 month to 18 years
People
1,800 worldwide
Run by
St. Anna Kinderkrebsforschung
See details and how to joinNCT01949129 · EU 2024-512657-24-00
Phase 2Taking people
Nivolumab in combination with cisplatin and 5-fluorouracil as induction therapy in children and adults with EBV-positive nasopharyngeal carcinoma
Where
Aachen, Berlin, Bielefeld, Bonn, Cologne, Cottbus, Dortmund, Dresden, Duesseldorf, Erlangen, Essen, Frankfurt Am Main, Freiburg im Breisgau, Giessen, Goettingen, Göttingen, Greifswald, Halle (saale), Hamburg, Jena, Kassel, Kiel, Magdeburg, Mainz, Mannheim, Muenster, Munich, Ratisbon, Tuebingen, Wuerzburg
Age
Up to 64 years
People
57
Run by
GPOH gGmbH
See details and how to join2022-500676-59-00
Phase 2Taking people
Study of Olutasidenib and Temozolomide in HGG
Where
Heidelberg
Age
12 years to 39 years
People
60 worldwide
Run by
Rigel Pharmaceuticals
See details and how to joinNCT06161974
Phase 2Taking people
Study to evaluate the safety and efficacy of asciminib in pediatric participants with chronic myeloid leukemia.
Where
Dresden, Erlangen, Essen, Frankfurt Am Main, Hamburg
Age
Up to 17 years
People
16 worldwide
Run by
Novartis Pharma AG
See details and how to join2025-522138-29-00
No phaseTaking people
Intraoperative Confocal Laser Scanning Microscopy With Use of AI for Optimized Surgical Excision of Basal Cell Carcinoma
Where
Munich
People
1,000
Run by
LMU Klinikum
See details and how to joinNCT06600165
No phaseTaking people
German Adrenocortical Carcinoma Registry
Where
Würzburg
People
1,000
Run by
University of Wuerzburg
See details and how to joinNCT00453674
No phaseEnrolling by invitation
ADLs at the End of Acute Treatment for Childhood Leukemia and Non-Hodgkin Lymphoma
Where
Munich
Age
4 years to 18 years
People
20
Run by
Technical University of Munich
See details and how to joinNCT05235633
No phaseTaking people
Cerebellar Mutism Syndrome Study
Where
Leipzig, Tübingen
Age
Up to 18 years
People
2,000 worldwide
Run by
Copenhagen University Hospital, Rigshospitalet
See details and how to joinNCT02300766
Phase 3Taking people
A Treatment Study Protocol for Participants 0-45 Years With Acute Lymphoblastic Leukaemia
Where
Bielefeld, Bonn, Bremen, Hamburg, Krefeld, Mainz
Age
0 years to 45 years
People
6,430 worldwide
Run by
Mats Heyman
See details and how to joinNCT04307576 · EU 2022-501050-11-01
Phase 1Enrolling by invitation
Adoptive Cell Therapy Long-term Follow-up (LTFU) Study
Where
Cologne, Munich
People
250 worldwide
Run by
USWM CT, LLC
See details and how to joinNCT03391778
Phase 2Taking people
A Master Protocol (LY900023) That Includes Several Clinical Trials of Drugs for Children and Young Adults With Cancer
Where
Essen, Freiburg im Breisgau, Hamburg
Age
1 year to 39 years
People
105 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT05999994
No phaseTaking people
Fit to Fight Childhood Cancer
Where
Mainz
Age
3 years to 21 years
People
100
Run by
Johannes Gutenberg University Mainz
See details and how to joinNCT05867186
Phase 2Taking people
Revumenib Treatment in Combination with FLA Chemotherapy in Paediatric Refractory/Relapsed KMT2A-r, NUP98-r or NPM1-mut Acute Myeloid Leukemia (AML)
Where
Augsburg, Erlangen, Freiburg im Breisgau, Hamburg, Jena, Mainz, Muenster
Age
Up to 64 years
People
31 worldwide
Run by
Pediatric Research International GmbH
See details and how to join2025-521390-14-00
No phaseTaking people
Health Effects of CArdiac FluoRoscopy and MOderN RadIotherapy in PediatriCs - Radiotherapy
Where
Essen
Age
Up to 22 years
People
2,670 worldwide
Run by
Institut National de la Santé Et de la Recherche Médicale, France
See details and how to joinNCT04746729
Phase 2Taking people
A Study to Assess the Efficacy and Safety of FORE8394 in Participants With Cancer Harboring BRAF Alterations
Where
Berlin, Frankfurt am Main, Heidelberg
Age
8 years and over
People
254 worldwide
Run by
Fore Biotherapeutics
See details and how to joinNCT05503797 · EU 2024-513578-23-00
Phase 3Taking people
VO and Nivolumab vs Physician's Choice in Advanced Melanoma That Progressed on Anti-PD-1 & Anti-CTLA-4 Drugs [IGNYTE-3]
Where
Berlin, Dresden, Erfurt, Essen, Frankfurt Am Main, Hamburg, Heidelberg, Kiel, Mainz, Munich, Tuebingen
Age
12 years and over
People
400 worldwide
Run by
Replimune, Inc.
See details and how to joinNCT06264180 · EU 2023-508612-29-00
Phase 1/2Taking people
Study of mRNA-4359 Administered Alone and in Combination With Immune Checkpoint Blockade in Participants With Advanced Solid Tumors
Where
Essen, Hamburg, Immenhausen, Minden
Age
12 years and over
People
361 worldwide
Run by
ModernaTX, Inc.
See details and how to joinNCT05533697 · EU 2023-504506-11-00
Phase 1Taking people
International open-label phase I dose escalation study of dinutuximab beta in combination with vincristine/doxorubicin/cyclophosphamide and ifosfamide/etoposide in pediatric, adolescent, and adult patients with GD2-positive Ewing sarcoma
Where
Berlin, Erlangen, Essen, Frankfurt Am Main, Freiburg im Breisgau, Goettingen, Greifswald, Hamburg, Heidelberg, Leipzig, Mainz
People
18 worldwide
Run by
GPOH gGmbH
See details and how to join2024-515245-42-00
Phase 1/2Taking people
A Study of Pembrolizumab (MK-3475) in Pediatric Participants With an Advanced Solid Tumor or Lymphoma (MK-3475-051/KEYNOTE-051)
Where
Muenster, Tuebingen
Age
6 months to 17 years
People
370 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to joinNCT02332668 · EU 2022-501257-36-00
Early phase 1Taking people
Lorlatinib for Newly-Diagnosed High-Grade Glioma With ROS or ALK Fusion
Where
Heidelberg
Age
1 year to 21 years
People
15 worldwide
Run by
Nationwide Children's Hospital
See details and how to joinNCT06333899
No phaseTaking people
SPECTA: Screening Cancer Patients for Efficient Clinical Trial Access
Where
Berlin, Dresden, Greifswald, Jena, Leer
Age
12 years and over
People
4,975 worldwide
Run by
European Organisation for Research and Treatment of Cancer - EORTC
See details and how to joinNCT02834884