Childhood cancers trials in Germany

In Germany 143 Also abroad 2481

143 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 2/3Taking people
SIOP Ependymoma II: An International Clinical Program for the diagnosis and treatment of children, adolescents and young adults with ependymoma
Where
Aachen, Augsburg, Berlin, Bielefeld, Bonn, Bremen, Brunswick, Dortmund, Dresden, Duisburg, Erfurt, Erlangen, Essen, Frankfurt Am Main, Freiburg im Breisgau, Giessen, Goettingen, Greifswald, Halle Saale, Hamburg, Hanover, Heidelberg, Heilbronn, Herdecke, Homburg, Jena, Karlsruhe, Kassel, Kiel, Koblenz, Krefeld, Leipzig, Luebeck, Magdeburg, Mainz, Mannheim, Minden, Muenster, Munich, Oldenburg, Regensburg, Rostock, Sankt Augustin, Schwerin, Stuttgart, Tuebingen, Ulm, Wuerzburg
Age
Up to 64 years
People
894 worldwide
Run by
Centre Leon Berard
See details and how to joinNCT02265770 · EU 2024-512222-28-00
Phase 2Taking people
Study of Ribociclib and Everolimus in HGG and DIPG or Ribociclib and Temozolomide in DHG, H3G34-mutant
Where
Heidelberg
Age
12 months to 39 years
People
120 worldwide
Run by
Nationwide Children's Hospital
See details and how to joinNCT05843253
Phase 1/2Taking people
A Study of Repotrectinib (TPX-0005) in Patients With Advanced Solid Tumors Harboring ALK, ROS1, or NTRK1-3 Rearrangements
Where
Dresden, Heidelberg
Age
12 years and over
People
500 worldwide
Run by
Turning Point Therapeutics, Inc.
See details and how to joinNCT03093116 · EU 2024-512606-25-00
Phase 2/3Taking people
Cardiorespiratory Fitness in Children and Adolescents After Cancer Treatment.
Where
Krefeld
Age
7 years to 23 years
People
56
Run by
Universität Duisburg-Essen
See details and how to joinNCT04765020
Phase 3Taking people
Study on chemotherapy and experimental drugs in patients with Philadelphia Chromosome positive and ABL-class Philadelphia Chromosome-Like B-cell Acute Lymphoblastic Leukemia
Where
Aachen, Augsburg, Berlin, Bremen, Dortmund, Dresden, Düsseldorf, Erlangen, Essen, Frankfurt, Freiburg im Breisgau, Giessen, Hamburg, Hannover, Heidelberg, Homburg, Kiel, Leipzig, Mainz, Münster, Stuttgart, Tübingen, Ulm
Age
Up to 64 years
People
87 worldwide
Run by
Universita Degli Studi Di Milano Bicocca
See details and how to join2025-520982-39-00
Phase 1/2Taking people
A phase 1B of crizotinib either in combination or as single agent in pediatric patients with ALK, ROS1 or MET positive malignancies
Where
Berlin, Essen, Frankfurt Am Main, Hamburg, Muenster
Age
Up to 64 years
People
72 worldwide
Run by
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
See details and how to join2023-504880-18-00
No phaseTaking people
Adrenal Tumors - Pathogenesis and Therapy
Where
Würzburg
Age
Up to 100 years
People
500
Run by
University of Wuerzburg
See details and how to joinNCT00669266
Phase 3Taking people
International Cooperative Treatment Protocol for Children and Adolescents With Lymphoblastic Lymphoma
Where
Aachen, Augsburg, Berlin, Bielefeld, Bonn, Bremen, Brunswick, Cologne, Cottbus, Datteln, Dortmund, Dresden, Duesseldorf, Erfurt, Erlangen, Essen, Frankfurt Am Main, Freiburg im Breisgau, Giessen, Goettingen, Greifswald, Halle (Saale), Hamburg, Hanover, Heidelberg, Herdecke, Homburg, Jena, Karlsruhe, Kassel, Kiel, Koblenz, Krefeld, Leipzig, Luebeck, Magdeburg, Mainz, Mannheim, Minden, Muenster, Munich, Nuernberg, Oldenburg, Regensburg, Rostock, Sankt Augustin, Schwerin, Stuttgart, Tuebingen, Ulm, Wuerzburg
Age
Up to 18 years
People
683 worldwide
Run by
University Hospital Muenster
See details and how to joinNCT04043494 · EU 2023-508101-24-00
Phase 2Taking people
Safety and Efficacy Study of Zamtocabtagene Autoleucel (MB-CART2019.1) in Pediatric Patients With R/R B-Cell Neoplasms
Where
Münster
Age
6 months to 17 years
People
31 worldwide
Run by
Miltenyi Biomedicine GmbH
See details and how to joinNCT06508931 · EU 2023-506348-17-00
No phaseTaking people
Study for Epidemiology and Characterization of Myelodysplastic Syndromes (MDS) and Juvenile Myelomonocytic Leucemia (JMML) in Childhood
Where
Freiburg im Breisgau
Age
Up to 17 years
People
260
Run by
University Hospital Freiburg
See details and how to joinNCT00662090
No phaseTaking people
Diagnostic Value of Exome/ Genome Sequencing, Conventional Methods in Rare Diseases and Familial Tumor Syndromes
Where
Tübingen
People
12,000
Run by
University Hospital Tuebingen
See details and how to joinNCT04731857
Phase 1/2Taking people
Personalized Vaccination in Fusion+ Sarcoma Patients (PerVision)
Where
Berlin, Dresden, Essen, Frankfurt Am Main, Freiburg, Munich, Tuebingen
Age
2 years to 40 years
People
30
Run by
University Hospital Tuebingen
See details and how to joinNCT06094101 · EU 2024-511337-35-00
No phaseTaking people
Physical Activity Directly Before Immunotherapy (Nivolumab and Ipilimumab) in Melanoma
Where
Hamburg
People
40
Run by
Universitätsklinikum Hamburg-Eppendorf
See details and how to joinNCT07564570
No phaseTaking people
MPN Childhood Registry
Where
Erlangen
Age
0 years to 17 years
People
500
Run by
University of Erlangen-Nürnberg Medical School
See details and how to joinNCT07410247
Phase 2Taking people
Tovorafenib for Treatment of Craniopharyngioma in Children and Young Adults
Where
Heidelberg
Age
1 year to 39 years
People
57 worldwide
Run by
Sabine Mueller, MD, PhD
See details and how to joinNCT05465174 · EU 2024-511510-20-00
Phase 3Taking people
ONC201 in H3 K27M-mutant Diffuse Glioma Following Radiotherapy (the ACTION Study)
Where
Augsburg, Berlin, Bonn, Cologne, Essen, Frankfurt Am Main, Heidelberg, Mannheim, Regensburg, Tuebingen
People
510 worldwide
Run by
Jazz Pharmaceuticals
See details and how to joinNCT05580562 · EU 2022-502051-56-00
Phase 2/3Taking people
A Randomized, Phase 2/3 Study to Investigate the Efficacy and Safety of RP2 in Combination With Nivolumab in Immune Checkpoint Inhibitor-Naïve Adult Patients With Metastatic Uveal Melanoma
Where
Berlin, Hamburg, Heidelberg
Age
18 years and over
People
280 worldwide
Run by
Replimune, Inc.
See details and how to joinNCT06581406 · EU 2023-508784-68-00
Early phase 1Taking people
A Pilot Study of Larotrectinib for Newly-Diagnosed High-Grade Glioma With NTRK Fusion
Where
Augsburg, Berlin, Cologne, Goettingen, Heidelberg
Age
Up to 21 years
People
15 worldwide
Run by
Nationwide Children's Hospital
See details and how to joinNCT04655404 · EU 2023-508953-16-00
Phase 2Taking people
International Study for Treatment of High Risk Childhood Relapsed ALL 2010
Where
Aachen, Augsburg, Berlin, Bielefeld, Bonn, Bremen, Brunswick, Cologne, Cottbus, Datteln, Dortmund, Dresden, Duesseldorf, Erfurt, Erlangen, Essen, Frankfurt Am Main, Freiburg im Breisgau, Giessen, Goettingen, Greifswald, Halle Saale, Hamburg, Herdecke, Homburg, Jena, Karlsruhe, Kassel, Kiel, Koblenz, Leipzig, Magdeburg, Mainz, Muenster, Munich, Oldenburg, Regensburg, Rostock, Sankt Augustin, Schwerin, Stuttgart, Tuebingen, Ulm, Wuerzburg
Age
Up to 17 years
People
250 worldwide
Run by
Charite University, Berlin, Germany
See details and how to joinNCT03590171 · EU 2024-513070-21-00
Phase 2Taking people
A study to determine how safe MB-CART2019.1 is and how well it works in children and adolescents with B cell neoplasms
Where
Muenster
Age
Up to 17 years
People
12 worldwide
Run by
Miltenyi Biomedicine GmbH
See details and how to joinNCT06508951
Phase 1Enrolling by invitation
Long-Term Follow-Up of AvenCell Sponsored CAR-T Cell Clinical Trials
Where
Berlin, Dresden, Marburg, Munich, Ulm
Age
18 years and over
People
178
Run by
AvenCell Therapeutics, Inc.
See details and how to joinNCT07474051 · EU 2025-521717-67-00
No phaseTaking people
Primary Tumor Research and Outcomes Network
Where
Dresden
People
1,350 worldwide
Run by
AO Innovation Translation Center
See details and how to joinNCT02790983
No phaseTaking people
Outcomes of Low-Risk Endometrial Cancer With Isolated Tumor Cells in the Sentinel Lymph Nodes: A Prospective, Multicenter, Single-Arm Observational Study
Where
Essen
People
212 worldwide
Run by
Mayo Clinic
See details and how to joinNCT06689956
No phaseTaking people
Digital Solutions for bEtter cAre
Where
Homburg
Age
12 years and over
People
200 worldwide
Run by
European Institute of Oncology
See details and how to joinNCT07416513
No phaseTaking people
Impact of Thyroid Hormones on Human Glucose and Energy Metabolism
Where
Ulm
People
60
Run by
University of Ulm
See details and how to joinNCT07410637