Chronic kidney disease trials in South Africa

5 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

• Phase 3Taking people
  A Phase III Renal Outcomes and Cardiovascular Mortality Study to Investigate the Efficacy and Safety of Baxdrostat in Combination With Dapagliflozin in Participants With Chronic Kidney Disease and High Blood Pressure

  Where

  Bellville, Benoni, Bloemfontein, Cape Town, Durban, Johannesburg, KwaDukuza, Lenasia, Midrand, Newton, Parow

  Age

  18 years and over

  People

  5,000 worldwide

  Run by

  AstraZeneca

  See details and how to joinNCT06742723 · EU 2023-506460-14-00
• Phase 3Taking people
  A Study of Orforglipron (LY3502970) on Cardiovascular Outcomes in Adults With Atherosclerotic Cardiovascular Disease and/or Chronic Kidney Disease (ATTAIN-Outcomes)

  Where

  Cape Town, Johannesburg, Paarl, Sommerset West, Worcester

  Age

  50 years and over

  People

  7,140 worldwide

  Run by

  Eli Lilly and Company

  See details and how to joinNCT07241390 · EU 2025-523123-22-00
• Phase 3Taking people
  A Rollover Extension Program (REP) to Evaluate the Long-term Safety and Tolerability of Open Label Iptacopan/LNP023 in Participants With Primary IgA Nephropathy

  Where

  Bloemfontein

  Age

  18 years to 100 years

  People

  540 worldwide

  Run by

  Novartis Pharmaceuticals

  See details and how to joinNCT04557462 · EU 2023-508690-92-00
• Phase 3Taking people
  A Study to Learn More About How Safe the Study Treatment Finerenone is in Long-term Use When Taken With an ACE Inhibitor or Angiotensin Receptor Blocker Over 18 Months of Use in Children and Young Adults From 1 to 18 Years of Age With Chronic Kidney Disease and Proteinuria

  Where

  Soweto

  Age

  1 year to 18 years

  People

  100 worldwide

  Run by

  Bayer

  See details and how to joinNCT05457283 · EU 2023-504885-50-00
• No phaseTaking people
  iCaReMe Global Registry: Multinational Real-world Evidence in Cardiorenal and Metabolic Diseases

  Where

  Florida, Parow, Umhlanga

  Age

  18 years and over

  People

  35,000 worldwide

  Run by

  AstraZeneca

  See details and how to joinNCT03549754