Liver cirrhosis trials in France

In France 45 Also abroad 358

45 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
Where
Angers, Clichy, Créteil, Le Chesnay, Lille, Limoges, Lyon, Marseille, Montpellier Cedex 5, Nice, Paris, Pessac, Strasbourg, Toulouse, Vandœuvre-lès-Nancy
Age
18 years to 80 years
People
2,150 worldwide
Run by
Akero Therapeutics, Inc
See details and how to joinNCT06528314
Phase 3Taking people
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis
Where
Amiens Cedex 1, Angers, Clichy, Dijon, Le Chesnay Rocquencourt, Lille Cedex, Lyon Cedex 04, Nice, Paris, Toulouse Cedex 9, Assistance Publique-Hopitaux de Paris (AP-HP) - Hopitaux Universitaires Henri Mondor (Hopital Henri-, CHU Bordeaux Hopital Haut-Lévêque, HCL - Hopital Lyon Sud - Endocrinologie Diabetologie Nutrition
Age
18 years and over
People
1,590 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06632457 · EU 2024-513741-36-00
No phaseTaking people
Establishing a Reference Framework for Outcomes After Machine-Preserved Liver Transplantation in Europe
Where
Clermont-Ferrand, Clichy, Lyon, Strasbourg, Villejuif
Age
18 years and over
People
10,000 worldwide
Run by
University Medical Center Groningen
See details and how to joinNCT07585890
No phaseTaking people
Effect of Acute Endurance Exercise on the Production of FGF21 and Follistatin in Patients With Hepatocellular Carcinoma
Where
Clermont-Ferrand
Age
18 years to 80 years
People
12
Run by
University Hospital, Clermont-Ferrand
See details and how to joinNCT07189624
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
Where
Amiens Cedex 1, Clichy, Dijon, Limoges Cedex 1, Lyon Cedex 04, Montpellier Cedex 5, Nice, Paris, Pessac, Strasbourg Cedex, Toulouse Cedex 3, Toulouse Cedex 9, Vandoeuvre Les Nancy, Vénissieux, Villejuif
Age
18 years to 75 years
People
1,800 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT06419374 · EU 2023-510395-31-00
No phaseTaking people
"Constitution of a Biological Collection to Establish Preclinical Translational Models for the Study of Tumors and Chronic Liver Diseases".
Where
Strasbourg
Age
18 years and over
People
800
Run by
Institut National de la Santé Et de la Recherche Médicale, France
See details and how to joinNCT04690972
No phaseNot yet taking people in France
"Anticipant"-TIPS After a First Portal-hypertension-related Complication in Cirrhosis
Where
Besançon, Créteil, Lyon, Marseille, Nantes, Paris, Rennes, Toulouse
Age
18 years to 65 years
People
266
Run by
University Hospital, Toulouse
See details and how to joinNCT07889726
No phaseTaking people
Sexual Dysfunction in Cirrhosis
Where
Paris
Age
18 years and over
People
230
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT05428267
No phaseTaking people
4D-Flow MRI Assessment of Portal Hypertension and TIPS Outcomes in Cirrhosis
Where
Paris
Age
18 years and over
People
60
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT07554183
Phase 2Taking people
A Novel COMBinATorial Therapy With Albumin and Enoxaparin in Patients With Decompensated Cirrhosis at High-risk of Poor Outcome (COMBAT Trial).
Where
Clichy
Age
18 years to 80 years
People
90 worldwide
Run by
European Foundation for Study of Chronic Liver Failure
See details and how to joinNCT05895136 · EU 2023-507073-18-00
Phase 2Taking people
Portal hypertension in cirrhosis
Where
Bobigny, Clichy, Créteil, Creteil Cedex, Paris, St Denis Cedex, Suresnes, Villejuif
Age
18 years and over
People
76
Run by
Assistance Publique Hopitaux De Paris
See details and how to join2023-508535-32-00
No phaseTaking people
LEOPARD Training and Validation Data Collection Study
Where
Besançon, Chambray-lès-Tours, Clichy, Créteil, Dijon, Lille, Lyon, Marseille, Montpellier, Nice, Paris, Pessac, Rennes, Strasbourg, Toulouse, Villejuif
Age
18 years to 70 years
People
4,500 worldwide
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT06675604
No phaseTaking people
LEOPARD Prospective Validation Cohort 1
Where
Clichy, Créteil, Montpellier, Paris
Age
18 years to 70 years
People
630 worldwide
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT06723275
No phaseTaking people
Screening of Patients With Hepatic Fibrosis or Cirrhosis B and C
Where
Bobigny
Age
18 years and over
People
600
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT06755632
Phase 1Taking people
Evaluation of Cirrhotic Cardiomyopathy by Cardiac MRI in Patients Waiting for Liver Transplant.
Where
Besançon, Dijon, Nancy, Strasbourg
Age
18 years to 70 years
People
60
Run by
Centre Hospitalier Universitaire de Besancon
See details and how to joinNCT06327308
No phaseNot yet taking people in France
Development of a Predictive Score for the Risk of Infection in the Immediate Post-liver-transplant Period
Where
Clermont-Ferrand, Lyon, Montpellier
Age
18 years and over
People
279
Run by
Hospices Civils de Lyon
See details and how to joinNCT07647978
No phaseTaking people
mSEPT9 Biomarker for Predicting Hepatocellular Carcinoma Occurrence in Patients With Cirrhosis
Where
Vandœuvre-lès-Nancy
Age
18 years and over
People
400
Run by
Central Hospital, Nancy, France
See details and how to joinNCT06778317
No phaseTaking people
ProspEXPO : Study of the Associations Between Hepatocellular Carcinoma and Chemical and Psychosocial Environmental EXPOsome
Where
Angers, Rennes, Tours
Age
18 years and over
People
300
Run by
University Hospital, Angers
See details and how to joinNCT07119957
No phaseTaking people
Study of Genetic Determinants in Alcoholic Hepatitis and Establishment of a Multicenter Prospective Cohort of Patients With Alcoholic Liver Disease
Where
Angers, Besançon, Bondy, Caen, La Tronche, Lille, Marseille, Montpellier, Paris
Age
18 years and over
People
447
Run by
University Hospital, Lille
See details and how to joinNCT04106518
No phaseTaking people
PSYLIVER-PILOTE: Involvement of the Autonomic Nervous System in Hepatocellular Carcinoma (HCC)
Where
Lyon
Age
18 years and over
People
100
Run by
Hospices Civils de Lyon
See details and how to joinNCT07393074
No phaseTaking people
A Randomized Controlled Study Evaluating Bariatric Surgery as a Treatment for Severe NASH With Advanced Liver Fibrosis in Non-severe Obese Patients
Where
Lille
Age
18 years to 65 years
People
100
Run by
University Hospital, Lille
See details and how to joinNCT03472157
No phaseTaking people
Exploration of Systemic and Portal Hemostasis in Patients Undergoing Transjugular Intrahepatic Portosystemic Shunt Placement
Where
Villejuif
Age
18 years and over
People
45
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT07439939
No phaseTaking people
CHronic Hepatopathies Associated With ALcohol Consumption aNd metAbolic Syndrome
Where
Nice
Age
18 years and over
People
710
Run by
Institut National de la Santé Et de la Recherche Médicale, France
See details and how to joinNCT05623150
No phaseTaking people
Evaluation of Patient Care Support for Cirrhosis and/or Liver Transplants
Where
Paris
Age
18 years and over
People
3,000
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT06544863
No phaseTaking people
FAST-IRM for HCC suRveillance in pAtients With High risK of Liver Cancer.
Where
Bondy
Age
18 years and over
People
944
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT05095714