Liver cirrhosis trials in Germany

In Germany 26 Also abroad 358

26 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 13 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study Evaluating Efruxifermin in Subjects With Compensated Cirrhosis Due to NASH/MASH
Where
Berlin, Frankfurt am Main, Gent, Homburg, Leipzig, Lübeck
Age
18 years to 80 years
People
2,150 worldwide
Run by
Akero Therapeutics, Inc
See details and how to joinNCT06528314
Phase 3Taking people
LIVERAGE™ - Cirrhosis: A Study to Test Whether Survodutide Helps People With a Liver Disease Called NASH/MASH Who Have Cirrhosis
Where
Berlin, Bochum, Cologne, Dresden, Frankfurt Am Main, Heidelberg, Homburg, Landshut, Luebeck, Magdeburg, Mainz, Mannheim, Muenster, Wiesbaden, Wuerzburg
Age
18 years and over
People
1,590 worldwide
Run by
Boehringer Ingelheim
See details and how to joinNCT06632457 · EU 2024-513741-36-00
No phaseTaking people
Establishing a Reference Framework for Outcomes After Machine-Preserved Liver Transplantation in Europe
Where
Aachen, Berlin, Bonn, Essen, Hanover, Heidelberg, Magdeburg, München, Münster, Tübingen
Age
18 years and over
People
10,000 worldwide
Run by
University Medical Center Groningen
See details and how to joinNCT07585890
No phaseNot yet taking people in Germany
Within-Session Repeatability of EUS-Guided Portal Pressure Gradient Measurement
Where
Münster
Age
18 years and over
People
150 worldwide
Run by
University Hospital Muenster
See details and how to joinNCT07877298
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of Pegozafermin in Participants With Compensated Cirrhosis Due to MASH
Where
Chemnitz, Frankfurt Am Main, Freiburg im Breisgau, Hanover, Homburg, Muenster
Age
18 years to 75 years
People
1,800 worldwide
Run by
Hoffmann-La Roche
See details and how to joinNCT06419374 · EU 2023-510395-31-00
No phaseTaking people
Endohepatology-Based Reclassification of Treatment Indication in High-Risk MASLD
Where
Münster
Age
18 years and over
People
500
Run by
University Hospital Muenster
See details and how to joinNCT07877272
Phase 2Taking people
A Novel COMBinATorial Therapy With Albumin and Enoxaparin in Patients With Decompensated Cirrhosis at High-risk of Poor Outcome (COMBAT Trial).
Where
Aachen, Muenster
Age
18 years to 80 years
People
90 worldwide
Run by
European Foundation for Study of Chronic Liver Failure
See details and how to joinNCT05895136 · EU 2023-507073-18-00
No phaseTaking people
Acquisition of Cardiac Function Parameters in MRI and Echocardiography in Patients With Ethyltoxic Liver Cirrhosis and Transjugular Intrahepatic Portosystemic Shunt (TIPSS) Placement
Where
Jena
Age
18 years to 99 years
People
80
Run by
Stephanie Gräger
See details and how to joinNCT06814990
No phaseTaking people
LEOPARD Training and Validation Data Collection Study
Where
Aachen, Berlin, Hanover, Jena, Kiel, Leipzig, Münster, Tübingen, Würzburg
Age
18 years to 70 years
People
4,500 worldwide
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT06675604
No phaseTaking people
LEOPARD Prospective Validation Cohort 1
Where
Kiel
Age
18 years to 70 years
People
630 worldwide
Run by
Assistance Publique - Hôpitaux de Paris
See details and how to joinNCT06723275
Phase 2Taking people
Encapsulated Fecal Microbiota Transfer to Treat Immune Activation in Patients with Cirrhosis and Ascites (TransImmune) – A randomized, double-blind, placebo-controlled phase IIa clinical pilot study
Where
Aachen
Age
18 years and over
People
24
Run by
Universitaetsklinikum Aachen AöR
See details and how to join2023-507790-18-00
No phaseTaking people
Freiburg TIPS Registry
Where
Freiburg im Breisgau
Age
18 years to 100 years
People
2,000
Run by
University Hospital Freiburg
See details and how to joinNCT05782556
No phaseTaking people
Early TIPS in Patients With Liver Cirrhosis and Ascites
Where
Freiburg im Breisgau
Age
18 years to 80 years
People
134
Run by
University Hospital Freiburg
See details and how to joinNCT06576934
No phaseNot yet taking people in Germany
Clinical Characterization of Patients With Primary Biliary Cirrhosis Treated With Seladelpar in the Real-life Setting
Where
Berlin, Frankfurt, Hamburg, Hanover, Heidelberg, Herne, Homburg, Jena, Kiel, Leipzig, Leverkusen, Lübeck, München, Münster, Nuremberg, Tübingen, Wiesbaden
Age
18 years and over
People
100 worldwide
Run by
University of Leipzig
See details and how to joinNCT07549607
Phase 3Taking people
Personalized Long-term Human Albumin Treatment in Patients With Decompensated Cirrhosis and Ascites
Where
Berlin, Jena, Münster
Age
18 years and over
People
240 worldwide
Run by
Aleksander Krag
See details and how to joinNCT05056220
No phaseTaking people
Liver Transplantation in Patients With CirrHosis and Severe Acute-on-Chronic Liver Failure: iNdications and outComEs
Where
Aachen, Berlin, Frankfurt, Hamburg, Hanover, Heidelberg, Jena, Kiel, Leipzig, Mainz, Munich, Münster, Regensburg, Tübingen
Age
18 years to 80 years
People
3,000 worldwide
Run by
European Foundation for Study of Chronic Liver Failure
See details and how to joinNCT04613921
Phase 3Taking people
An European multinational study of a personalized approach of human albumin administration in patients with cirrhosis of the liver and complications
Where
Berlin, Jena, Muenster
Age
18 years and over
People
200 worldwide
Run by
Odense University Hospital
See details and how to join2022-501006-34-01
No phaseTaking people
TIPS in Patients With Decompensated Liver Cirrhosis
Where
Hanover
Age
18 years to 99 years
People
250
Run by
Hannover Medical School
See details and how to joinNCT04801290
No phaseTaking people
Health Literacy and Self-efficacy Expectations in Patients With Alcohol-related Liver Cirrhosis
Where
Hanover
Age
18 years to 99 years
People
200
Run by
Hannover Medical School
See details and how to joinNCT07169526
No phaseTaking people
Assessment of Liver Diseases Using a Deep-Learning Approach Based on Ultrasound RF-Data
Where
Dresden, Halle, Leipzig
Age
18 years and over
People
200
Run by
Technische Universität Dresden
See details and how to joinNCT06317181
Phase 4Taking people
Stop of Proton-pump Inhibitor Treatment in Patients With Liver Cirrhosis - a Double-blind, Placebo-controlled Trial
Where
Aachen, Berlin, Bonn, Brandenburg An Der Havel, Dresden, Essen, Frankfurt Am Main, Freiburg im Breisgau, Halle Saale, Hamburg, Hanover, Homburg, Jena, Leipzig, Luebeck, Mainz, Muenster, Rostock, Tuebingen
Age
18 years and over
People
476
Run by
Universitätsklinikum Hamburg-Eppendorf
See details and how to joinNCT04448028 · EU 2023-509863-26-00
No phaseTaking people
Influence of Sarcopenia on the Course of the Diseases
Where
Mainz
Age
18 years and over
People
200
Run by
Universitatsmedizin Mainz - 1. Medizinische Klinik
See details and how to joinNCT06829290
No phaseTaking people
HRS-AKI Treatment With TIPS in Patients With Cirrhosis
Where
Aachen, Berlin, Dresden, Essen, Freiburg im Breisgau, Halle, Hamburg, Hanover, Jena, Landshut, Leipzig, Ludwigsburg, Munich, Münster
Age
18 years to 80 years
People
124
Run by
Jena University Hospital
See details and how to joinNCT05346393
No phaseTaking people
The European NAFLD Registry
Where
Aachen, Berlin, Freiburg im Breisgau, Mainz, Würzburg
Age
18 years to 100 years
People
10,000 worldwide
Run by
Newcastle University
See details and how to joinNCT04442334
No phaseTaking people
Non-Invasive Characterization of Focal Liver Lesions in Liver Cirrhosis
Where
Bonn
Age
18 years to 99 years
People
200
Run by
University Hospital, Bonn
See details and how to joinNCT03746210