Colorectal cancer trials in Czechia

In Czechia 16 Also abroad 1930

16 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Study to Test the Safety and Tolerability of PF-07220060 in Participants With Advance Solid Tumors
Where
Olomouc, Prague
Age
18 years and over
People
430 worldwide
Run by
Pfizer
See details and how to joinNCT04557449 · EU 2024-512120-11-00
Phase 3Taking people
Phase III Study of Ivonescimab or Bevacizumab Combined With FOLFOX in Patients With Metastatic Colorectal Cancer
Where
Brno, Hradec Králové, Olomouc, Prague
Age
18 years and over
People
900 worldwide
Run by
Summit Therapeutics
See details and how to joinNCT07228832
No phaseTaking people
MRD Monitoring in Colorectal Cancer Using ctDNA
Where
Brno
Age
18 years and over
People
60
Run by
Masaryk Memorial Cancer Institute
See details and how to joinNCT07895459
Phase 2Taking people
A Study to Evaluate the Adverse Events, and Efficacy of Intravenous (IV) of Telisotuzumab Adizutecan in Combination With IV Oxaliplatin, Fluorouracil, Folinic Acid/Leucovorin, Bevacizumab, Panitumumab in Adult Participants With Metastatic Colorectal Cancer
Where
Brno-Stred, Hradec Králové, Prague, Prague 4
Age
18 years and over
People
390 worldwide
Run by
AbbVie
See details and how to joinNCT06820463 · EU 2024-512981-33-00
Phase 3Not yet taking people in Czechia
Study of Petosemtamab Plus Chemotherapy Versus Cetuximab Plus Chemotherapy in RAS and BRAF Wild-type, Unresectable or Metastatic, Left-sided Colorectal Cancer.
Where
Brno, Brno-Stred, Hořovice, Hradec Králové, Prague
Age
18 years and over
People
450 worldwide
Run by
Genmab A/S
See details and how to join2026-525883-17-00 · EU 2026-525883-17-00
Phase 2/3Taking people
A Study to Evaluate the Safety and Efficacy of Pumitamig in Combination With Chemotherapy Versus Bevacizumab in Combination With Chemotherapy in Participants With Previously Untreated, Unresectable, or Metastatic Colorectal Cancer
Where
Brno-Stred, Hradec Králové, Olomouc, Prague
Age
18 years and over
People
990 worldwide
Run by
Bristol-Myers Squibb
See details and how to joinNCT07221357 · EU 2025-523224-45-00
Phase 2Taking people
Evaluation of the Safety and Efficacy of Treatment w/High Dose Melphalan Given Directly Into the Liver Followed by Treatment w/Approved Cancer Treatment or Approved Cancer Treatment Alone in Patients w/ Metastatic Colorectal Cancer w/Liver Dominant Disease
Where
Prague
Age
18 years and over
People
90 worldwide
Run by
Delcath Systems Inc.
See details and how to joinNCT06607458
Phase 3Taking people
A Randomized, Active-Controlled, Double-blind, Multicenter, Phase 3 Clinical Study of Ivonescimab in Combination with FOLFOX versus Bevacizumab in Combination with FOLFOX for the First-line Treatment of Metastatic Colorectal Cancer (HARMONi-GI3)
Where
Brno-Stred, Hradec Králové, Olomouc, Prague, Prague 2
Age
18 years and over
People
230 worldwide
Run by
Summit Therapeutics Inc.
See details and how to join2025-521587-35-00 · EU 2025-521587-35-00
Phase 3Taking people
A clinical trial of belzutifan and other treatments in people with solid tumors or von Hippel-Lindau (VHL)-related tumors (MK-6482-043)
Where
Brno-Stred, Olomouc, Prague
Age
18 years and over
People
134 worldwide
Run by
Merck Sharp & Dohme LLC
See details and how to join2025-524160-38-00 · EU 2025-524160-38-00
Phase 1/2Taking people
A Study to Assess Safety and Efficacy of SOT109 in Patients With Advanced Unresectable or Metastatic Colorectal Cancer
Where
Brno-Stred
Age
18 years and over
People
100 worldwide
Run by
SOTIO Biotech a.s.
See details and how to joinNCT07693751 · EU 2026-526235-19-00
Phase 3Taking people
Study of Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Participants With Metastatic Colorectal Cancer With KRAS p.G12C Mutation
Where
Brno, Hradec Králové, Olomouc, Prague
Age
18 years and over
People
450 worldwide
Run by
Amgen
See details and how to joinNCT06252649
Phase 3Taking people
Sotorasib, Panitumumab and FOLFIRI Versus FOLFIRI With or Without Bevacizumab-awwb in Treatment-naïve Subjects With Metastatic Colorectal Cancer With KRAS p.G12C Mutation (CodeBreaK 301)
Where
Brno-Stred, Novy Hradec Kralove, Olomouc, Prague, Prague 10, Prague 5
Age
18 years to 64 years
People
241 worldwide
Run by
Amgen Inc.
See details and how to join2022-502352-31-00 · EU 2022-502352-31-00
Phase 2Taking people
Randomized Study to Evaluate Melphalan/HDS Treatment Followed by Trifluridine–tipiracil plus Bevacizumab Versus Trifluridine–tipiracil plus Bevacizumab Alone in Metastatic Colorectal Cancer Patients
Where
Prague
Age
18 years and over
People
35 worldwide
Run by
Delcath Systems Inc.
See details and how to join2024-520356-24-00 · EU 2024-520356-24-00
Phase 2Taking people
An Evaluation of NGM120 in a Randomized, Double-blind, Placebo-controlled Study in Participants With Colorectal Cancer Who Have Cancer Cachexia.
Where
Brno-Stred, Hořovice, Novy Knin, Prague
Age
18 years and over
People
136 worldwide
Run by
NGM Biopharmaceuticals, Inc
See details and how to joinNCT07033026 · EU 2025-521730-28-00
Phase 3Taking people
Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
Where
Hradec Králové, Nový Jičín, Prague
Age
18 years and over
People
892 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT05855200 · EU 2023-503265-27-00
No phaseTaking people
Rectal Cancer CTC Trial
Where
Olomouc, Ostrava
Age
18 years and over
People
120
Run by
University Hospital Ostrava
See details and how to joinNCT07194616