Colorectal cancer trials in Germany

In Germany 104 Also abroad 1941

104 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 14 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
ColoReg: A Register for Gastrointestinal Endoscopy Reports and Examination Videos
Where
Stuttgart, Würzburg
Age
18 years and over
People
1,834
Run by
Wuerzburg University Hospital
See details and how to joinNCT06920680
Phase 3Taking people
Post-resection/Ablation Chemotherapy in Patients With Metastatic Colorectal Cancer (FIRE-9 - PORT / AIO-KRK-0418)
Where
Amberg, Bad Saarow, Bayreuth, Berlin, Bochum, Bonn, Chemnitz, Cologne, Darmstadt, Deggendorf, Dessau-Rosslau, Dresden, Duesseldorf, Essen, Frankfurt am Main, Frankfurt Am Main, Freiburg im Breisgau, Fürth, Georgsmarienhuette, Giessen, Goettingen, Halle (Saale), Hamburg, Hanover, Herne, Homburg, Jena, Landshut, Leer (ostfriesland), Leipzig, Lemgo, Leverkusen, Ludwigsburg, Magdeburg, Mainz, Marburg, Minden, Muenster, Munich, Neumuenster, Neuss, Nuremberg, Passau, Potsdam, Ravensburg, Regensburg, Reutlingen, Rheine, Rostock, Schwäbisch Hall, Siegen, Stuttgart, Trier, Ulm, Weilheim, Wetzlar, Wuerzburg, Wuppertal
Age
18 years and over
People
507
Run by
Dominik Paul Modest
See details and how to joinNCT05008809 · EU 2024-512174-10-00
Phase 2Taking people
- IKF/AIO-QUINTIS - Evaluating Fruquintinib in Combination With Tislelizumab in Microsatellite Stable / Proficient Mismatch Repair (MSS/pMMR) Metastatic Colorectal Cancer Without Active Liver Metastases
Where
Amberg, Bad Saarow, Berlin, Bochum, Düsseldorf, Essen, Frankfurt, Frankfurt am Main, Hamburg, Herne, Karlsruhe, München, Schweinfurt, Trier, Ulm
Age
18 years and over
People
140 worldwide
Run by
Institut für Klinische Krebsforschung IKF GmbH at Krankenhaus Nordwest
See details and how to joinNCT06856837
Phase 3Taking people
The Sagittarius Trial
Where
Berlin
Age
18 years and over
People
700 worldwide
Run by
IFOM ETS - The AIRC Institute of Molecular Oncology
See details and how to joinNCT06490536 · EU 2023-509851-15-00
Phase 2Not yet taking people in Germany
5-fluorouracil Plus Panitumumab (Anti-EGFR) and Sotorasib (KRAS G12C Inhibitor) in First-line Treatment of Patients Non-eligible for a Doublet/Triplet Chemotherapy With Advanced Unresectab
Where
Bad Saarow, Berlin, Bochum, Dresden, Frankfurt am Main, Goettingen, Hamburg, Kiel, Landshut, Reutlingen, Rheine, Riesa, Rostock, Schweinfurt
Age
18 years and over
People
300 worldwide
Run by
Federation Francophone de Cancerologie Digestive
See details and how to joinNCT07124884 · EU 2024-514030-20-00
No phaseTaking people
Low Stable Pressure Pneumoperitoneum in Colorectal Surgery (CROSS STUDY)
Where
Eisenach
Age
18 years and over
People
300 worldwide
Run by
Bordeaux Colorectal Institute Academy
See details and how to joinNCT06154785
Phase 2Taking people
Total Neoadjuvant Treatment With or Without Tislelizumab for Locally Advanced Rectal Cancer.
Where
Freiburg im Breisgau, Hamburg, Mainz, Ulm, Wuerzburg
Age
18 years and over
People
134 worldwide
Run by
brenner baruch
See details and how to joinNCT06940388 · EU 2025-522120-28-00
No phaseTaking people
ColoCare Study - Colorectal Cancer Cohort
Where
Heidelberg
Age
18 years to 89 years
People
5,000 worldwide
Run by
University of Utah
See details and how to joinNCT02328677
No phaseEnrolling by invitation
DESI - Düsseldorfer ESD Study
Where
Düsseldorf
Age
18 years and over
People
1,000
Run by
Torsten Beyna
See details and how to joinNCT06993402
Phase 1Taking people
FIH, Bispecific CD276xCD3 Antibody CC-3 in Patients With Colorectal Cancer
Where
Tübingen
Age
18 years and over
People
89
Run by
German Cancer Research Center
See details and how to joinNCT05999396
No phaseTaking people
Predicting Cancer Risk With Digital and Molecular Markers
Where
Please Refer to Project Homepage For Details (see Link Below)
Age
18 years and over
People
1,250
Run by
University of Erlangen-Nürnberg Medical School
See details and how to joinNCT06962670
Phase 3Not yet taking people in Germany
Pre-Operative Treatment in REseCTable COlon CanceR
Where
Amberg, Augsburg, Bad Saarow, Berlin, Bielefeld, Bochum, Borna, Chemnitz, Cologne, Darmstadt, Deggendorf, Dessau-Rosslau, Dortmund, Duesseldorf, Düsseldorf, Erlangen, Essen, Frankfurt am Main, Frankfurt Am Main, Freiburg im Breisgau, Goettingen, Greifswald, Hamburg, Hamm, Hannover, Heidelberg, Herne, Hildesheim, Hof, Jena, Landshut, Leipzig, Leverkusen, Lüdenscheid, Ludwigsburg, Luebeck, Magdeburg, Mannheim, Meschede, Muenster, München, Munich, Münster, Neumuenster, Nürnberg, Offenbach Am Main, Oldenburg, Ostfildern, Paderborn, Ravensburg, Recklinghausen, Regensburg, Reutlingen, Rheine, Rosenheim, Rostock, Saarbruecken, Schweinfurt, Schwerin, Siegen, Singen (Hohentwiel), Speyer, Stade, Traunstein, Trier, Villingen-Schwenningen, Weinheim, Wetzlar, Winnenden, Witten, Wolfsburg, Wuppertal, Würzburg
Age
18 years to 120 years
People
714
Run by
Dominik Paul Modest
See details and how to joinNCT06899477 · EU 2023-508076-11-00
No phaseTaking people
Comparison of the Physical Activity in Cancer Patients Assessed by Questionnaire and Motion Tracker
Where
Greifswald
Age
18 years and over
People
60
Run by
University Medicine Greifswald
See details and how to joinNCT05501379
No phaseTaking people
Stereotactic Body Radiotherapy in Patients With Rare Oligometastatic Cancers (OligoRARE)
Where
Hamburg
Age
18 years and over
People
200 worldwide
Run by
European Organisation for Research and Treatment of Cancer - EORTC
See details and how to joinNCT04498767
Phase 2Taking people
OPTIMIzation of Treatment SElection and Follow up in Oligometastatic Colorectal Cancer
Where
Hamburg
Age
18 years and over
People
350 worldwide
Run by
Karen-Lise Garm Spindler
See details and how to joinNCT04680260 · EU 2023-509814-12-00
No phaseTaking people
Living Donor Liver Transplantation With Two Stage Hepatectomy for Patients With Isolated, Irresectable Colorectal Liver Metastases
Where
Jena, Tübingen
Age
18 years and over
People
40
Run by
Jena University Hospital
See details and how to joinNCT03488953
Phase 2/3Taking people
Sacituzumab Govitecan in Metastatic Colorectal Cancer
Where
Berlin, Dresden, Essen, Frankfurt am Main, Freiburg im Breisgau, Hamburg, Heidelberg, Munich, Tuebingen, Witten
Age
18 years and over
People
80
Run by
University Hospital Heidelberg
See details and how to joinNCT06243393 · EU 2023-509771-17-00
No phaseTaking people
Anatomical Resection of Liver MetAstases iN patIents With RAS-mutated Colorectal Cancer
Where
Ansbach, Augsburg, Berlin, Bonn, Braunschweig, Dachau, Dortmund, Dresden, Düsseldorf, Erlangen, Frankfurt, Freiburg im Breisgau, Giessen, Göttingen, Greifswald, Halle, Hamburg, Hanover, Heidelberg, Jena, Lübeck, Magdeburg, Mainz, Mannheim, Marburg, München, Munich, Münster, Oldenburg, Tübingen, Ulm, Wuppertal, Würzburg
Age
18 years and over
People
240
Run by
Technische Universität Dresden
See details and how to joinNCT04678583
Phase 3Taking people
Performance of SGM-101 for the Delineation of Primary and Recurrent Tumor and Metastases in Patients Undergoing Surgery for Colorectal Cancer
Where
Göttingen
Age
18 years and over
People
300 worldwide
Run by
Surgimab
See details and how to joinNCT03659448
Phase 2Taking people
Trifluridine/ Tipiracil Plus Panitumumab Versus Trifluridine/ Tipiracil Plus Bevacizumab as First-line Treatment of Metastatic Colorectal Cancer
Where
Amberg, Aschaffenburg, Augsburg, Bamberg, Bayreuth, Berlin, Bochum, Bruchsal, Chemnitz, Dessau-Rosslau, Dingolfing, Düsseldorf, Essen, Esslingen, Freiburg, Göttingen, Hildesheim, Kiel, Köln, Krefeld, Landshut, Leer, Magdeburg, Minden, München, Paderborn, Ravensburg, Rosenheim, Schweinfurt, Ulm, Wangen im Allgäu
Age
18 years and over
People
153
Run by
Dominik Paul Modest
See details and how to joinNCT05007132 · EU 2024-513723-16-00
Phase 2Not yet taking people in Germany
Hyperthermia Enhanced Re-irradiation of Loco-regional Recurrent Tumors
Where
Berlin
Age
18 years and over
People
110
Run by
Charite University, Berlin, Germany
See details and how to joinNCT04889742
No phaseTaking people
Amplitude Modulated Radiofrequency Electromagnetic Field Treatment Combined With TAS-102 (Lonsurf) and Bevacizumab in Refractory Metastatic Colorectal Cancer
Where
Berlin
Age
18 years and over
People
12
Run by
Charite University, Berlin, Germany
See details and how to joinNCT05991102
No phaseTaking people
Online Adaptive Radiotherapy Using a Novel Linear Accelerator (ETHOS)
Where
Berlin
Age
18 years and over
People
649
Run by
Charite University, Berlin, Germany
See details and how to joinNCT06116019
No phaseTaking people
Lymph Node Mapping Via Flourescent Dye in Colon Cancer
Where
Hamburg
Age
18 years to 100 years
People
30
Run by
Universitätsklinikum Hamburg-Eppendorf
See details and how to joinNCT04959604
No phaseTaking people
Establishment of a Tumor Bank for Blood Samples
Where
Berlin, Freiburg im Breisgau, Herne
Age
18 years and over
People
10,000 worldwide
Run by
Medical University of Vienna
See details and how to joinNCT01763125