Colorectal cancer trials in Netherlands

In Netherlands 86 Also abroad 1941

86 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 15 November 2026. Ask the study team whether a trial fits you.

Phase 3Active, not recruiting
Study of Perioperative Dostarlimab in Participants With Untreated T4N0 or Stage III dMMR/MSI-H Resectable Colon Cancer
Where
Breda, Maastricht, Nijmegen, Utrecht
Age
18 years and over
People
892 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT05855200 · EU 2023-503265-27-00
No phaseTaking people
Accuracy and Sustainability of SCALE-EYE Evaluation for Measuring Reliable Polyp Size
Where
Eindhoven, Leiden, Rotterdam
Age
55 years to 80 years
People
241
Run by
Erasmus Medical Center
See details and how to joinNCT07005453
No phaseTaking people
Feasibility of Circulating Tumour DNA (ctDNA) Analysis Using Automated Capillary Blood Sampling
Where
Rotterdam
Age
21 years and over
People
35
Run by
Erasmus Medical Center
See details and how to joinNCT07310537
Phase 2Not yet taking people in Netherlands
Neo-adjuvant intraperitoneal chemotherapy (irinotecan) and systemic chemotherapy (mFOLFOX4-bevacizumab) prior to CRS-HIPEC for patients with isolated resectable colorectal peritoneal metastases: a multicentre, phase II trial (INTERACT-PLUS)
Where
Amsterdam, Eindhoven, Rotterdam
Age
18 years and over
People
40
Run by
Erasmus Universitair Medisch Centrum Rotterdam (Erasmus MC)
See details and how to join2024-512318-16-00
Early phase 1Completed
PET-imaging of Two Vartumabs in Patients With Solid Tumors
Where
Groningen
Age
18 years and over
People
32
Run by
Var2 Pharmaceuticals
See details and how to joinNCT06645808 · EU 2024-513827-18-00
Phase 4Taking people
FARE Trial
Where
Amsterdam
Age
18 years and over
People
50
Run by
Amsterdam UMC
See details and how to join2023-506594-35-00
No phaseTaking people
Sentinel Node and Organ-sparing Surgery in Stage I Colon Carcinoma
Where
Amersfoort
Age
18 years and over
People
341
Run by
Meander Medical Center
See details and how to joinNCT06652672
Phase 1Taking people
Molecular imaging with FAPI for diagnosing the CSM4 colorectal cancer subtype
Where
Utrecht
Age
18 years and over
People
45
Run by
Universitair Medisch Centrum Utrecht
See details and how to join2023-509183-17-00
No phaseTaking people
Smart Pill for Measuring Gut Health in Colon Inflammation and Colon Cancer
Where
Nijmegen
Age
18 years and over
People
10
Run by
Radboud University Medical Center
See details and how to joinNCT07046468
No phaseTaking people
Smart Measurement of Circulating Tumor DNA
Where
Leiden, Rotterdam
Age
18 years and over
People
50
Run by
Erasmus Medical Center
See details and how to joinNCT06989814
No phaseTaking people
Impact of CES1 Genotype on Capecitabine Exposure in Cancer Patients
Where
Rotterdam
Age
18 years and over
People
66
Run by
Erasmus Medical Center
See details and how to joinNCT07114627 · EU 2024-516788-96-00
No phaseTaking people
Earlier Detection and Optimization of Treatment and Prognosis for Patients With Early-onset Colorectal Cancer
Where
Amsterdam
Age
18 years to 49 years
People
300
Run by
The Netherlands Cancer Institute
See details and how to joinNCT06568679
No phaseTaking people
Low Stable Pressure Pneumoperitoneum in Colorectal Surgery (CROSS STUDY)
Where
Amsterdam
Age
18 years and over
People
300 worldwide
Run by
Bordeaux Colorectal Institute Academy
See details and how to joinNCT06154785
No phaseNot yet taking people in Netherlands
OligoCare TwiCs (Trials Within Cohorts) Trial Comparing Acute Toxicity in Single-fraction vs Multiple-fraction SBRT for Metastasis-directed Treatment (SPRINT)
Where
Deventer, Nijmegen
People
302 worldwide
Run by
European Organisation for Research and Treatment of Cancer - EORTC
See details and how to joinNCT06462963
No phaseTaking people
Adaptive Anastomosis for Anterior Resection in Sigmoid and Proximal Rectal Cancer or Premalignant Lesions
Where
Amsterdam
Age
18 years and over
People
165
Run by
Amsterdam UMC, location VUmc
See details and how to joinNCT07056374
Phase 1/2Taking people
Dose Finding, Efficacy and Immunological Response of IP-001 Following MWA or IRE for CRLM
Where
Amsterdam
Age
18 years and over
People
120
Run by
M.R. Meijerink
See details and how to joinNCT06630624 · EU 2023-504572-25-00
No phaseTaking people
The Role of the Tumor Molecular Profile (CMS), UGT1A1 Genotype and Beta-glucuronidase Activity of the Intestinal Microbiota for Treatment Efficiency, Toxicity, Survival and Quality of Life in Patients With Metastatic or Unresectable Colorectal Cancer During Irinotecan-based Systemic Treatment
Where
Maastricht
Age
18 years and over
People
104
Run by
Maastricht University Medical Center
See details and how to joinNCT05655780
Phase 3Taking people
Induction Treatment for Initially Unresectable Colorectal Liver Metastases: Combined Hepatic Arterial Infusion Pump Therapy With Systemic Therapy
Where
Amsterdam
Age
18 years and over
People
306
Run by
The Netherlands Cancer Institute
See details and how to joinNCT06857773 · EU 2023-506194-35-00
Phase 3Taking people
A multi-centred, partially randomised, patient-preference trial of radical surgery versus adjuvant chemoradiotherapy after local excision for early rectal cancer.
Where
Alkmaar, Almere, Amsterdam, Apeldoorn, Arnhem, Breda, Capelle aan den IJssel, Deventer, Ede Gld, Eindhoven, Groningen, Hoofddorp, Leeuwarden, Leiden, Maastricht, Nieuwegein, Nijmegen, Roermond, Roosendaal, Rotterdam, 'S-Hertogenbosch, Tilburg, Utrecht, Vlissingen, Zwolle
Age
18 years and over
People
315 worldwide
Run by
Amsterdam UMC Stichting
See details and how to joinNCT02371304 · EU 2024-517410-15-01
No phaseTaking people
Gut Microbiome Dynamics in Metastasized or Irresectable Colorectal Cancer
Where
Assen, Drachten, Emmen, Enschede, Groningen, Heerenveen, Leeuwarden, Scheemda, Sneek
Age
18 years and over
People
300
Run by
University Medical Center Groningen
See details and how to joinNCT03941080
No phaseNot yet taking people in Netherlands
Evaluation of Gixam's Efficacy Predicting Pre-cancerous Colorectal Polyps and Colorectal Cancer
Where
Rotterdam
Age
50 years to 80 years
People
800
Run by
Jubaan Ltd.
See details and how to joinNCT06688110
No phaseTaking people
The DRAGON 2 Trial
Where
Amsterdam, Breda, Eindhoven, Groningen, Maastricht, Rotterdam, Utrecht
Age
18 years and over
People
348 worldwide
Run by
Maastricht University
See details and how to joinNCT05428735
Phase 3Taking people
DOSAGE Study: Upfront Dose-Reduced Chemotherapy in Older Patients with Metastatic Colorectal Cancer
Where
Alkmaar, Almelo, Amersfoort, Amstelveen, Amsterdam, Arnhem, Assen, Beugen, Beverwijk, Capelle aan den IJssel, Delft, Deventer, Doetinchem, Drachten, Ede Gld, Eindhoven, Emmen, Enschede, Goes, Gorinchem, Gouda, Harderwijk, Helmond, Hilversum, Hoofddorp, Leeuwarden, Leiden, Leiderdorp, Nieuwegein, Nijmegen, Roermond, Roosendaal, Rotterdam, Scheemda, Schiedam, 's-Gravenhage, 's-Hertogenbosch, Sneek, Terneuzen, Uden, Utrecht, Veldhoven, Venlo, Winterswijk, Zaandam, Zwolle
Age
70 years and over
People
587
Run by
Leiden University Medical Center
See details and how to joinNCT06275958 · EU 2023-506115-17-00
Phase 2Taking people
SGM-LARRC: Multicenter, open-label, controlled, parallel arms clinical study on the performance of SGM-101, a fluorochrome-labeled anti-carcino-embryonic antigen (CEA) monoclonal antibody, for locally advanced or recurrent rectal cancerpatients undergoing curative surgery.
Where
Amsterdam, Eindhoven, Groningen, Leiden, Leidschendam, Nijmegen, Rotterdam
Age
18 years and over
People
203
Run by
Academisch Ziekenhuis Leiden
See details and how to join2024-510768-21-00
No phaseTaking people
Patient-led Follow-up from Home After Surgery for Colorectal Carcinoma
Where
Breda, Capelle aan den IJssel, Leiden, Rotterdam
Age
21 years and over
People
200
Run by
Erasmus Medical Center
See details and how to joinNCT06613581