COPD trials in Spain

In Spain 34 Also abroad 559

27 of 34 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

No phaseTaking people
Comprehensive Maintenance Program: a Health Haven for COPD in Lleida.The NAPOLEON Project.
Where
Lleida
Age
40 years to 75 years
People
86
Run by
Institut de Recerca Biomèdica de Lleida
See details and how to joinNCT07394712
Phase 2Not yet taking people in Spain
The MAB Trial: A Study of Tozorakimab to Reduce Lung Inflammation and Promote Lung Healing in People with COPD.
Where
Barcelona, Palma
Age
18 years and over
People
60 worldwide
Run by
University Of Leicester
See details and how to join2025-522359-24-00 · EU 2025-522359-24-00
Phase 3Taking people
A Non-inferiority Pharmacokinetic and Safety/Tolerability Study of Two Different Doses of Weekly SC Alpha1-PI 15% Compared With Corresponding Standard IV Alpha1-PI in Participants With Alpha1-Antitrypsin Deficiency (AATD)
Where
Madrid, San Cristóbal de La Laguna, Seville, Vigo
Age
18 years to 80 years
People
40 worldwide
Run by
Grifols Therapeutics LLC
See details and how to joinNCT07555483 · EU 2025-522792-29-00
Phase 2Taking people
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Where
Benalmádena, Granollers, Madrid, Málaga, Mérida, Pozuelo de Alarcón, Santander
Age
40 years and over
People
987 worldwide
Run by
AstraZeneca
See details and how to joinNCT07082738
Phase 3Taking people
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
Where
Badalona, Barcelona, Chamberí, Madrid, Santander, Zaragoza
Age
40 years to 80 years
People
942 worldwide
Run by
Sanofi
See details and how to joinNCT07190222 · EU 2024-518213-25-00
Phase 2/3Taking people
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Where
Barcelona, Benalmádena, Granada, Málaga, Mérida, Pozuelo de Alarcón, Santander, Zaragoza
Age
35 years to 80 years
People
1,156 worldwide
Run by
Pfizer
See details and how to joinNCT07363694 · EU 2024-518587-12-00
Phase 4Taking people
A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.
Where
Barcelona, Madrid, Oviedo, Pozuelo de Alarcón, Santander
Age
40 years to 85 years
People
218 worldwide
Run by
Sanofi
See details and how to joinNCT07053423
Phase 3Taking people
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Where
Benalmádena, Cáceres, Jerez de la Frontera, L'Hospitalet de Llobregat, Málaga, Mérida, Palma, Seville
Age
40 years to 80 years
People
942 worldwide
Run by
Sanofi
See details and how to joinNCT07190209 · EU 2024-518016-39-00
Phase 4Taking people
This After Market Study is Seeing if Dupilumab Plus Usual Standard of Care (SOC) is Better Than Usual Care Alone for Adult Participants After a Severe Chronic Obstructive Pulmonary Disease (COPD) Flare-Up Requiring Hospitalization
Where
Cáceres, Girona, Granada, Santander, Santiago de Compostela
Age
40 years and over
People
754 worldwide
Run by
Regeneron Pharmaceuticals
See details and how to joinNCT07587658 · EU 2025-524392-23-00
Phase 2Not yet taking people in Spain
A Randomized, Double-Blind, Placebo-controlled, Parallel Arm, 52-week Study to Assess Efficacy, Safety, Tolerability, and Pharmacokinetics of Two Doses of EXPD-101 in Participants with COPD
Where
Badalona, Barcelona, Benalmádena, Granada, Madrid, Pamplona, Torrelavega, Vic, Zaragoza
Age
18 years and over
People
183 worldwide
Run by
Expedition Therapeutics Inc.
See details and how to join2026-525216-34-00 · EU 2026-525216-34-00
Phase 3Taking people
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation
Where
Alzira, Barcelona, Benalmádena, Ferrol, Galdakao, Madrid, Málaga, Marbella, Palma, Pamplona, Pozuelo de Alarcón, Santander, Sevilla, Zaragoza
Age
40 years to 80 years
People
981 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06959095 · EU 2024-520418-22-00
Phase 3Taking people
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
Where
Alicante, Barakaldo, Barcelona, Cabra, Cantabria, Granada, Illes Balears, Madrid, Málaga, Marbella, Mataro, Santa Cruz de Tenerife, Santiago de Compostela, Valencia
Age
40 years to 80 years
People
5,250 worldwide
Run by
AstraZeneca
See details and how to joinNCT06283966 · EU 2023-507407-59-00
No phaseTaking people
An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema
Where
Valencia
Age
40 years to 80 years
People
200 worldwide
Run by
Pulmonx Corporation
See details and how to joinNCT06035120
No phaseTaking people
Medical Device Clinical Trial Without CE Marking to Evidence Safety and Performance of the INBENTUS VERSATILE Ventilator in Patients Requiring Assisted/Controlled Mechanical Ventilation and Weaning.
Where
Murcia
Age
18 years and over
People
81
Run by
Iconic Solutions By Murcia SL
See details and how to joinNCT07432191
Phase 3Taking people
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
Where
Barakaldo, Barcelona, Granada, Madrid, Málaga, Palma, Pamplona, Sevilla, Valencia
Age
40 years to 80 years
People
990 worldwide
Run by
AstraZeneca
See details and how to joinNCT06883305 · EU 2024-517458-90-00
No phaseNot yet taking people in Spain
Extracorporeal Carbon Dioxide Removal Plus Noninvasive Ventilation in Patients With COPD Not Eligible for Intubation
Where
Barcelona
Age
18 years and over
People
14
Run by
Hospital del Mar Research Institute (IMIM)
See details and how to joinNCT07785375
Phase 2Taking people
A study to investigate the effect of AZD6793 in participants with moderate to very severe chronic obstructive pulmonary disease
Where
Benalmádena, Granollers, Madrid, Málaga, Mérida, Pozuelo de Alarcón, Santander
Age
18 years and over
People
307 worldwide
Run by
AstraZeneca AB
See details and how to join2025-520473-40-00 · EU 2025-520473-40-00
Phase 3Taking people
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
Where
Alcalá de Henares, Alzira, Barcelona, Benalmádena, Lleida, Madrid, Málaga, Palma, Pontevedra, Valladolid
Age
40 years to 75 years
People
1,196 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07177339 · EU 2025-521108-23-00
Phase 4Taking people
Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels
Where
Barcelona, Palma de Mallorca
Age
40 years and over
People
135 worldwide
Run by
Maria Joyera Rodríguez
See details and how to joinNCT06334575
Phase 1Not yet taking people in Spain
An Open Label Study to Assess the Effect of Patient Use and Robustness on Tiotropium Bromide Spray 2.5μg, Soft Mist Inhaler device
Where
Almería, Barcelona, L'hospitalet De Llobregat, Madrid, Salamanca, Santander, Sevilla, Valencia
Age
18 years and over
People
75
Run by
Laboratorios Liconsa S.A.
See details and how to join2025-522412-16-00 · EU 2025-522412-16-00
No phaseNot yet taking people in Spain
EFFECTIVENESS OF COMBINED CONCENTRIC AND ECCENTRIC AEROBIC EXERCISE ON A TREADMILL IN PATIENTS WITH COPD: A RANDOMIZED CLINICAL TRIAL.
Where
Madrid
Age
18 years and over
People
40
Run by
Universidad Europea de Madrid
See details and how to joinNCT07627035
Phase 4Taking people
Molecular signatures associated with response to ICS treatment in patients with COPD stratified by eosinophil levels
Where
Barcelona, Palma
Age
18 years to 64 years
People
60 worldwide
Run by
Fundacio De Recerca Clinic Barcelona-Institut D’investigacions Biomediques August Pi I Sunyer
See details and how to join2023-505245-13-00 · EU 2023-505245-13-00
No phaseEnrolling by invitation
Effect of an App-based Intervention on Air Pollution in COPD Patients
Where
Salamanca
Age
18 years and over
People
150
Run by
Fundacion para la Investigacion y Formacion en Ciencias de la Salud
See details and how to joinNCT07074093
Phase 3Not yet taking people in Spain
Exploring the Anti-ageing Effects of Metformin in COPD
Where
Barcelona, Cáceres, Las Palmas De Gran Canaria, Lleida, Logroño, Madrid, Palma, Pamplona, Santa Cruz de Tenerife, Santander, Valencia, Zaragoza
Age
40 years to 75 years
People
212
Run by
Fundación Instituto de Investigación Sanitaria de Navarra
See details and how to joinNCT06999343 · EU 2025-520972-24-00
No phaseTaking people
Integrated Approach in Frail Older People with Atrial Fibrillation
Where
Alicante, Cartagena, Cártama, Elche, Málaga, Murcia, Sant Joan d'Alacant, Tarragona, Valls
Age
65 years and over
People
1,250 worldwide
Run by
Heart Care Foundation
See details and how to joinNCT06775028