COPD trials in United Kingdom

In United Kingdom 51 Also abroad 558

27 of 51 trials · From ClinicalTrials.gov, checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
A Study of Brenipatide (LY3537031) in Adult Participants With Moderate-to-Severe Chronic Obstructive Pulmonary Disease (COPD)
Where
Cheadle, Ely, Hounslow, London, Penzance, West Kirby
Age
40 years to 75 years
People
606 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07759245 · EU 2026-525480-41-00
Phase 2Taking people
Phase 2b Efficacy and Safety Study of AERO-007, an Inhaled LABA+LAMA Combination for Nebulization Delivery in COPD Patients
Where
London, Manchester
Age
40 years to 75 years
People
64
Run by
AeroRx Therapeutics Inc.
See details and how to joinNCT07896252
Phase 2Taking people
A Study to Investigate the Effect of AZD6793 in Participants With Moderate to Very Severe Chronic Obstructive Pulmonary Disease
Where
Bradford, Cottingham, Glasgow, Harrow, London, Newcastle upon Tyne, Thetford, Wythenshawe
Age
40 years and over
People
987 worldwide
Run by
AstraZeneca
See details and how to joinNCT07082738
Phase 3Taking people
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD), Characterized by an Eosinophilic Phenotype
Where
Chertsey, London, Milton Keynes, Reading, Rotherham, Salford, Southampton
Age
40 years to 80 years
People
942 worldwide
Run by
Sanofi
See details and how to joinNCT07190222 · EU 2024-518213-25-00
Phase 2/3Taking people
A Study to Learn About the Study Medicine Called PF-07275315 in People With Moderate to Severe Chronic Obstructive Pulmonary Disease
Where
Bradford, Chertsey, Glasgow, Leicester, London, Manchester, North Shields
Age
35 years to 80 years
People
1,156 worldwide
Run by
Pfizer
See details and how to joinNCT07363694 · EU 2024-518587-12-00
Phase 2Taking people
Trial Comparing the Safety and Efficacy of Two Different Oral VPV Doses With Placebo as Treatment for RV in Participants With COPD
Where
Bromborough, Glasgow, London, Milton Keynes, Wolverhampton
Age
40 years to 85 years
People
180 worldwide
Run by
Altesa Biosciences, Inc.
See details and how to joinNCT07610395
Phase 3Enrolling by invitation
A Study to Evaluate the Long-term Safety and Efficacy of Lunsekimig in Adult Participants With Chronic Obstructive Pulmonary Disease (COPD)
Where
Chertsey, Rotherham
Age
40 years to 80 years
People
1,508 worldwide
Run by
Sanofi
See details and how to joinNCT07793409
Phase 4Taking people
A Study to Investigate Airway Inflammation With Dupilumab Subcutaneously in Participants Aged ≥40 to ≤85 Years With Chronic Obstructive Pulmonary Disease.
Where
Bradford, Dundee, Leicester, Newcastle upon Tyne, Sheffield, Southampton
Age
40 years to 85 years
People
218 worldwide
Run by
Sanofi
See details and how to joinNCT07053423
Phase 1/2Taking people
A Study of RO7830698 in Healthy Participants and Participants With Chronic Obstructive Pulmonary Disease
Where
Wythenshawe
Age
18 years to 80 years
People
104
Run by
Hoffmann-La Roche
See details and how to joinNCT07822334
No phaseTaking people
Bronchoscopic RElease of Air Trapped in Hyperinflated Emphysematous Lung - Study 3
Where
London
Age
40 years to 84 years
People
250 worldwide
Run by
Apreo Health, Inc.
See details and how to joinNCT06891755
Phase 3Taking people
Efficacy, Safety, and Tolerability Study of Lunsekimig Compared With Placebo in Adult Participants With Inadequately Controlled Chronic Obstructive Pulmonary Disease (COPD) Characterized by an Eosinophilic Phenotype
Where
Bradford, Bristol, Harrow, Leicester, London, Oxford, Worthing
Age
40 years to 80 years
People
942 worldwide
Run by
Sanofi
See details and how to joinNCT07190209 · EU 2024-518016-39-00
Phase 3Taking people
Depemokimab as an Extended Treatment Duration Biologic in Adults With Chronic Obstructive Pulmonary Disease (COPD) and Type 2 Inflammation (ENDURA-2)
Where
Bedford, Corby, Dagenham, Edinburgh, Glasgow, Llanelli, London, Manchester, Oxford, Portsmouth, Salford, Uxbridge
Age
40 years to 80 years
People
961 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT06961214 · EU 2024-520417-41-00
No phaseNot yet taking people in United Kingdom
Effectiveness of Pollution Monitoring in Clinical Exercise Rehabilitation
Where
Leicester
Age
18 years and over
People
80
Run by
University of Leicester
See details and how to joinNCT07500948
Phase 3Taking people
A Study Evaluating the Efficacy of Budesonide, Glycopyrronium and Formoterol Fumarate Metered Dosed Inhaler on Cardiopulmonary Outcomes in Chronic Obstructive Pulmonary Disease
Where
Bicester, Bollington, Bradford, Cardiff, Chesterfield, Corby, Cottingham, Fowey, Glasgow, Hounslow, Liverpool, London, Manchester, Newquay, Northallerton, North Somerset, Norwich, Nottingham, Perth, Poole, Sheffield, Torbay, Whitney, Witney
Age
40 years to 80 years
People
5,250 worldwide
Run by
AstraZeneca
See details and how to joinNCT06283966 · EU 2023-507407-59-00
Phase 4Taking people
A Study to Investigate the Effect of Budesonide/Glycopyrronium/Formoterol Fumarate Metered Dose Inhaler (BGF MDI) Compared With Placebo MDI on Heart and Lung Function in Participants With Chronic Obstructive Pulmonary Disease (COPD) and Hyperinflation
Where
Harefield, London, Manchester
Age
40 years to 80 years
People
56 worldwide
Run by
AstraZeneca
See details and how to joinNCT07073950 · EU 2025-521987-37-00
No phaseTaking people
An Evaluation of the AeriSeal System for CONVERTing Collateral Ventilation Status in Patients With Severe Emphysema
Where
London
Age
40 years to 80 years
People
200 worldwide
Run by
Pulmonx Corporation
See details and how to joinNCT06035120
Phase 3Taking people
A Study to Investigate the Efficacy and Safety of Tezepelumab in Adult Participants With Moderate to Very Severe COPD (D5241C00006)
Where
Bradford, Brighton, Cottingham, Glasgow, Halifax, Leeds, Portsmouth, Tyne and Wear, Wakefield
Age
40 years to 80 years
People
990 worldwide
Run by
AstraZeneca
See details and how to joinNCT06883305 · EU 2024-517458-90-00
Phase 1Taking people
To Identify if a COPD Self-management App Can Safety and Appropriately Identify When Patients Are Not on the Best Medication Plan for Their COPD Symptoms and Support Their COPD Management.
Where
Southampton
Age
18 years and over
People
746
Run by
University of Southampton
See details and how to joinNCT07797985
No phaseTaking people
Balance Training Following Pulmonary Rehabilitation on Balance in People With Chronic Obstructive Pulmonary Disease (COPD)
Where
Middlesbrough, Northallerton, Stockton-on-Tees
People
77
Run by
Samantha Harrison
See details and how to joinNCT07750821
Phase 3Taking people
eValuating the Efficacy and Safety of InitiatinG depemokImab earLy therApy iN Chronic Obstructive Pulmonary Disorder (COPD) With Type 2 Inflammation
Where
Bedford, Bradford, Corby
Age
40 years to 75 years
People
1,196 worldwide
Run by
GlaxoSmithKline
See details and how to joinNCT07177339 · EU 2025-521108-23-00
Phase 4Taking people
Molecular Signatures Associated With Response to ICS Treatment in Patients With COPD Stratified by Eosinophil Levels
Where
Leicester, London
Age
40 years and over
People
135 worldwide
Run by
Maria Joyera Rodríguez
See details and how to joinNCT06334575
No phaseTaking people
Strategy for EArly Recognition of Cancer, COPD & Heart Failure in the Emergency Department
Where
Glasgow
Age
18 years and over
People
17,000
Run by
NHS Greater Glasgow and Clyde
See details and how to joinNCT07391280
No phaseTaking people
Structured Review: To Optimise Management and Prevent Harm in COPD
Where
North Shields
Age
35 years and over
People
96
Run by
Northumbria Healthcare NHS Foundation Trust
See details and how to joinNCT07460154
No phaseTaking people
Reducing Chronic Breathlessness in Adults by Following a Self-guided, Internet Based Supportive Intervention (SELF-BREATHE)
Where
London
Age
18 years to 110 years
People
246
Run by
King's College Hospital NHS Trust
See details and how to joinNCT06326957
No phaseTaking people
Make Every Step Count: Personalised Music Feedback to Walking for People Living With COPD
Where
Leicester
Age
18 years and over
People
30
Run by
University of Leicester
See details and how to joinNCT06629675