Crohn's disease: open trials in Czechia

25 open trials have a site in Czechia. Registry data; only the trial team decides who can take part.

2024-518296-56-00
A clinical study of MK-7240 for the treatment of Crohn’s disease (MK-7240-008)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Pratia Czech s.r.o., Brno-Stred · Vojenska Nemocnice Brno, Brno-Zidenice · Hepato-Gastroenterologie HK, s.r.o., Hradec Králové · Institute for Clinical and Experimental Medicine, Prague · ISCARE a.s., Prague · Nemocnice Slany, Slaný
Registry updated 2026-11-08
NCT06226883
A Phase 2 Study to Evaluate MORF-057 in Adults With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 2 · Morphic Therapeutic, Inc. (A Wholly Owned Subsidiary of Eli Lilly and Company)
SurGal Clinic s.r.o., Brno-Sever · Vojenska Nemocnice Brno, Brno-Zidenice · Clinoxus s.r.o., Prague 4 · Axon Clinical s.r.o., Prague 5
Registry updated 2026-11-04
NCT06937099
Mirikizumab and Tirzepatide Administered in Adult Participants With Moderately to Severely Active Crohn's Disease and Obesity or Overweight
Trial Treatment · Phase 3 · Eli Lilly and Company
SurGal Clinic, Brno · Gastroenterologie, Hradec Králové · EndoArt, Ostrava · ResTrial GastroEndo s.r.o, Prague · ISCARE klinické centrum, Prague · Masarykova nemocnice v Usti nad Labem, Ústí nad Labem
Registry updated 2026-11-04
NCT06651281
Extension Study of Long-term Safety and Efficacy of Tulisokibart in Participants With Crohn's Disease or Ulcerative Colitis (MK-7240-011)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Vojenska Nemocnice Brno, Brno-Zidenice · Hepato-Gastroenterologie HK, s.r.o., Hradec Králové
Registry updated 2026-11-03
NCT07196722
A Study of Icotrokinra in Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 2/3 · Janssen Research & Development, LLC
Fakultni nemocnice Brno, Brno · Vojenska Nemocnice Brno, Brno-Zidenice · Centrum gastroenterologie a hepatologie s.r.o., Kladno · PreventaMed, s.r.o., Olomouc · MUDr. Michal Konecny Ph.D. s.r.o., Olomouc · Gastromedic s.r.o, Pardubice · Axon Clinical s.r.o., Prague · Nemocnice Milosrdnych Sester Sv. Karla Boromejskeho V Praze, Prague · Fakultni nemocnice Kralovske Vinohrady, Prague · Clinoxus s.r.o., Prague 4
Registry updated 2026-11-03
NCT07499232
A Study of Guselkumab Versus Risankizumab in Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Fakultni nemocnice Brno, Brno · Vojenská Nemocnice Brno, Brno · Gastroenterologie, s.r.o., Hradec Kralove, Hradec Kralova · Hepato-Gastroenterologie HK, s.r.o., Hradec Králové · Fakultni Nemocnice Ostrava, Ostrava - Poruba · Fakultni Thomayerova nemocnice, Prague · Fakultni nemocnice Kralovske Vinohrady, Prague
Registry updated 2026-11-03
NCT07577843
A Study of JNJ-78934804 in Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 3 · Janssen Research & Development, LLC
Hepato-Gastroenterologie HK, s.r.o., Hradec Králové · Oblastni nemocnice Kladno a.s. nemocnice Stredoceskeho kraje, Kladno · Fakultni nemocnice Ostrava, Ostrava · Fakultni Thomayerova nemocnice, Prague · Institute for Clinical and Experimental Medicine, Prague · ISCARE a.s., Prague
Registry updated 2026-11-03
NCT06233461
A Study on the Safety of TAK-279 and Whether it Can Reduce Inflammation in the Bowel of Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 2 · Takeda
Fakultni nemocnice Brno, Brno · SurGal Clinic s.r.o., Brno-Sever · Vojenska Nemocnice Brno, Brno-Zidenice · Nemocnice České Budějovice, a.s., České Budějovice · Hepato-Gastroenterologie HK, s.r.o., Hradec Králové · PreventaMed, s.r.o., Olomouc · Fakultni nemocnice Ostrava, Ostrava · Gastromedic s.r.o, Pardubice · Endohope klinika s.r.o., Prague · Fakultni nemocnice Kralovske Vinohrady, Prague · Axon Clinical s.r.o., Prague 5 · EndoArt s.r.o., Slezska Ostrava · Krajská zdravotní a.s. - Masarykova nemocnice Ústí nad Labem, o.z., Ústí nad Labem
Registry updated 2026-11-02
NCT06430801
A Study to Evaluate the Efficacy and Safety of Tulisokibart (MK-7240) in Participants With Moderate to Severe Crohn's Disease (MK-7240-008)
Trial Treatment · Phase 3 · Merck Sharp & Dohme LLC
Pratia Czech s.r.o., Brno-Stred · Vojenska Nemocnice Brno, Brno-Zidenice · Hepato-Gastroenterologie HK, s.r.o., Hradec Králové · Institute for Clinical and Experimental Medicine, Prague · ISCARE a.s., Prague · Nemocnice Slany, Slaný
Registry updated 2026-11-02
NCT06958536
A Study to Investigate Efficacy and Safety of Brivekimig in Participants With Crohn's Disease
Trial Treatment · Phase 2 · Sanofi
Vojenska Nemocnice Brno, Brno-Zidenice · Nemocnice České Budějovice, a.s., České Budějovice · Hepato-Gastroenterologie HK, s.r.o., Hradec Králové · PreventaMed, s.r.o., Olomouc · Nemocnice Slany, Slaný
Registry updated 2026-11-02
NCT06819891
A Study to Assess the Efficacy and Safety of Induction Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 3 · Hoffmann-La Roche
Hepato-Gastroenterologie HK, s.r.o., Hradec Králové · Gastroenterologie s.r.o., Hradec Králové · Fakultni nemocnice Ostrava, Ostrava · Institute for Clinical and Experimental Medicine, Prague · ISCARE a.s., Prague · Krajska zdravotni a.s., Usti Nad Labem
Registry updated 2026-10-26
NCT07184931
An Induction Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 3 · Sanofi
Brno · Brno · Brno · Hradec Králové · Prague · Prague
Registry updated 2026-10-21
NCT07184944
A Maintenance Study to Investigate the Efficacy and Safety of Duvakitug in Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 3 · Sanofi
Hradec Králové · Prague
Registry updated 2026-10-21
NCT05995353
A Study to Assess Adverse Events, Change in Disease Activity, and How Intravenous and Subcutaneous Risankizumab Moves Through the Body of Pediatric Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 3 · AbbVie
Fakultni Nemocnice Hradec Kralove, Novy Hradec Kralove · Vseobecna Fakultni Nemocnice V Praze, Prague 2 · Fakultni Nemocnice V Motole, Prague 5
Registry updated 2026-10-20
NCT07884045
Impact of Ultra-Processed Food Reduction on Remission Duration in Pediatric Crohn's Disease
Trial Treatment · University Hospital, Motol
Department of Paediatric Gastroenterology, University Hospital Motol and Homolka, Prague · University Hospital Motol and Homolka, Prague
Registry updated 2026-10-20
NCT06819878
A Study to Assess the Efficacy and Safety of Induction and Maintenance Therapy With Afimkibart (RO7790121) in Participants With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 3 · Hoffmann-La Roche
SurGal Clinic s.r.o., Brno-Sever · Nemocnice České Budějovice, a.s., České Budějovice · Gastroenterologie s.r.o., Hradec Králové · Fakultni Nemocnice Hradec Kralove, Novy Hradec Kralove
Registry updated 2026-10-16
2026-525197-19-00
A clinical trial to assess the efficacy and safety of ontunisertib compared to placebo in patients with fibrostenosing Crohn’s disease
Trial Treatment · Phase 2 · Agomab Spain S.L.U.
Fakultni nemocnice Brno, Brno · SurGal Clinic s.r.o., Brno-Sever · Vojenska Nemocnice Brno, Brno-Zidenice · ISCARE a.s., Prague
Registry updated 2026-10-14
NCT06548542
Study of Targeted Therapies for the Treatment of Adult Participants With Moderate to Severe Crohn's Disease
Trial Treatment · Phase 2 · AbbVie
SurGal Clinic s.r.o., Brno-Sever · Hepato-Gastroenterologie HK, s.r.o., Hradec Králové · ISCARE a.s., Prague
Registry updated 2026-09-25
2025-521590-13-00
Crohn’s Head-to-Head Assessing Risankizumab Versus Guselkumab for One Year
Trial Treatment · Phase 3 · Janssen Cilag International
Fakultni nemocnice Brno, Brno · Vojenska Nemocnice Brno, Brno-Zidenice · Gastroenterologie s.r.o., Hradec Králové · Hepato-Gastroenterologie HK, s.r.o., Hradec Králové · Fakultni nemocnice Ostrava, Ostrava · Fakultni nemocnice Kralovske Vinohrady, Prague · Fakultni Thomayerova nemocnice, Prague
Registry updated 2026-08-28
NCT06227910
A Study of Vedolizumab With and Without Upadacitinib in Adults With Crohn's Disease
Trial Treatment · Phase 3 · Takeda
Nemocnice České Budějovice, a.s., České Budějovice · Fakultni nemocnice Hradec Kralove, Hradec Králové · Hepato-Gastroenterologie HK, s.r.o., Hradec Králové · ISCARE a.s., Prague
Registry updated 2026-05-27
NCT06764615
A Continuation Study of TAK-279 in Adults With Ulcerative Colitis (UC) and Crohn's Disease (CD)
Trial Treatment · Phase 2 · Takeda
Fakultni nemocnice Brno, Brno · SurGal Clinic s.r.o., Brno-Sever · Vojenska Nemocnice Brno, Brno-Zidenice · Nemocnice České Budějovice, a.s., České Budějovice · Hepato-Gastroenterologie HK, s.r.o., Hradec Králové · Fakultni nemocnice Ostrava, Ostrava · Gastromedic s.r.o, Pardubice · Endohope klinika s.r.o., Prague · Fakultni nemocnice Kralovske Vinohrady, Prague · Axon Clinical s.r.o., Prague 5 · EndoArt s.r.o., Slezska Ostrava · Krajska zdravotni a.s., Usti Nad Labem
Registry updated 2026-05-22
NCT05442567
A Study of Vedolizumab in Children With Ulcerative Colitis (UC) or Crohn's Disease (CD)
Trial Treatment · Phase 3 · Takeda
Fakultni nemocnice Kralovske Vinohrady, Prague · Fakultni Thomayerova nemocnice, Prague
Registry updated 2026-05-07
NCT04779320
A Study of Vedolizumab in Children and Teenagers With Moderate to Severe Crohn's Disease (CD)
Trial Treatment · Phase 3 · Takeda
Fakultni nemocnice Ostrava, Ostrava · Fakultni nemocnice Kralovske Vinohrady, Prague · Fakultni Thomayerova nemocnice, Prague
Registry updated 2026-05-05
NCT06456593
Efficacy and Safety of Obefazimod in Subjects With Moderately to Severely Active Crohn's Disease
Trial Treatment · Phase 2 · Abivax S.A.
SurGal Clinic s.r.o., Brno-Sever · Vojenska Nemocnice Brno, Brno-Zidenice · Hepato-Gastroenterologie HK, s.r.o., Hradec Králové · PreventaMed, s.r.o., Olomouc · ISCARE a.s., Prague · Nemocnice Slany, Slaný
Registry updated 2026-04-27
NCT06257706
VECTORS - A Study to Evaluate Transmural Healing as a Treatment Target in Crohn's Disease
Trial Treatment · Phase 4 · Alimentiv Inc.
Fakultni nemocnice Brno, Brno · Vojenská Nemocnice Brno, Brno
Registry updated 2026-01-15

All Crohn's disease trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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