Cystic fibrosis trials in Italy

In Italy 13 Also abroad 188

13 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 12 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients With Cystic Fibrosis
Where
Milan
Age
18 years and over
People
64 worldwide
Run by
SpliSense Ltd.
See details and how to joinNCT06429176
Phase 2Taking people
A Study of 24 to 52 Weeks Treatment to Evaluate The Efficacy And Safety of Galvokimig in Adult Study Participants With Non-Cystic Fibrosis Bronchiectasis
Where
Milan, Monza, Palermo, Pavia, Rozzano
Age
18 years to 80 years
People
300 worldwide
Run by
UCB Biopharma SRL
See details and how to joinNCT07720375 · EU 2026-525524-18-00
Phase 2Taking people
Early Study on Tamoxifen Safety/Tolerability in Cystic Fibrosis Patients Unable to Use CFTR Modulators.
Where
Verona
Age
18 years to 64 years
People
35
Run by
Azienda Ospedaliera Universitaria Integrata Verona
See details and how to joinNCT07289035 · EU 2024-519657-11-00
Phase 2Taking people
A Phase II Study of Ensifentrine in Non-Cystic Fibrosis Bronchiectasis
Where
Bologna, Catania, Genoa, Monza, Pavia, Reggio Emilia, Rome, Rozzano
Age
18 years to 80 years
People
284 worldwide
Run by
Verona Pharma, Inc., a subsidiary of Merck & Co., Inc. (Rahway, New Jersey USA
See details and how to joinNCT06559150 · EU 2024-514845-12-00
No phaseTaking people
A Precision Medicine Approach to Assess Protein Function Loss and the Potential for CFTR Function Restoration in Cystic Fibrosis and Related Disorders
Where
Catania, Genova, Milan
Age
28 days to 65 years
People
165
Run by
Istituto Giannina Gaslini
See details and how to joinNCT07889973
Phase 2Taking people
Dose Range Finding, Efficacy, and Safety Study of Nebulized CSL787 in Adults With Non-cystic Fibrosis Bronchiectasis (NCFB)
Where
Bergamo, Foggia, Milan, Modena, Monza, Pavia, Rozzano, Trieste
Age
18 years to 85 years
People
180 worldwide
Run by
CSL Behring
See details and how to joinNCT07048262 · EU 2024-518821-13-00
Phase 4Taking people
Pharmacokinetics of Elexacaftor/Tezacaftor/Ivacaftor in Cystic Fibrosis
Where
Florence, Genoa, Milan, Trieste
Age
6 years and over
People
50
Run by
Istituto Giannina Gaslini
See details and how to joinNCT07809867 · EU 2024-518785-28-00
Phase 2Taking people
A Study to Evaluate Safety and Explore Efficacy of New Lipase NHS7108 in Adult Participants With Exocrine Pancreatic Insufficiency.
Where
Catania, Florence, Messina, Milan, Roma, Rozzano
Age
18 years to 85 years
People
66 worldwide
Run by
Aimmune Nestlé Health Science US R&D, LLC
See details and how to joinNCT07559175
Phase 2Taking people
Safety, Tolerability, Pharmacokinetics, and Preliminary Efficacy of SPL84 in Patients with Cystic Fibrosis
Where
Catania, Messina, Milan
Age
18 years and over
People
30 worldwide
Run by
Splisense Ltd.
See details and how to join2024-511184-28-00
Phase 2Not yet taking people in Italy
Safety and Efficacy of VX-828/Deutivacaftor Combination Therapy With and Without Tezacaftor in Subjects With Cystic Fibrosis
Where
Florence, Milan, Rome, Verona
Age
18 years and over
People
80 worldwide
Run by
Vertex Pharmaceuticals Inc.
See details and how to join2025-523400-72-00
No phaseTaking people
Impact of Elexacaftor-Tezacaftor-Ivacaftor Treatment on Metabolic, Epigenetic and Fecal Microbiota Profiles in People With Cystic Fibrosis.
Where
Bari, Florence, Milan, Naples, Roma, Torino
Age
2 years and over
People
150
Run by
Meyer Children's Hospital IRCCS
See details and how to joinNCT07363304
Phase 2Taking people
An open-label study to evaluate the safety and tolerability of inhaled Teicoplanin in the treatment of Staphylococcus aureus (including mrsa) infections in cystic fibrosis patients
Where
Milan, Verona
Age
Up to 64 years
People
12
Run by
Azienda Ospedaliera Universitaria Integrata Verona
See details and how to join2024-517820-21-00
No phaseTaking people
Identification of New Biological Markers for the Progression of Mycobacterium Abscessus-induced Lung Disease in Cystic Fibrosis
Where
Milan
Age
18 years and over
People
40
Run by
Ospedale San Raffaele
See details and how to joinNCT06413459