Depression trials in Australia

In Australia 12 Also abroad 666

12 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Where
Carlton, Elizabeth Vale, Geelong, Melbourne, Northcote, Toowoomba, Westmead
Age
18 years to 75 years
People
1,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07412756 · EU 2025-522308-25-00
Phase 3Taking people
A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder
Where
Brisbane, Bruce, Carlton, Elizabeth Vale, Geelong, Melbourne, Toowoomba, Westmead
Age
18 years to 75 years
People
1,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07775300 · EU 2025-522310-24-00
Phase 3Taking people
A Study of a Deuterated Psilocin Analog (CYB003) in Humans With Major Depressive Disorder
Where
Camperdown, Maroochydore, Melbourne, Notting Hill
Age
18 years to 85 years
People
330 worldwide
Run by
Cybin IRL Limited
See details and how to joinNCT06793397 · EU 2024-519270-40-00
Phase 3Taking people
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Where
Carlton, Melbourne
Age
18 years and over
People
850 worldwide
Run by
Neurocrine Biosciences
See details and how to joinNCT06966401 · EU 2024-519423-24-00
Phase 3Taking people
A Study to Evaluate the Maintenance Effect of Osavampator as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Where
Carlton, Melbourne, Parkville
Age
18 years and over
People
550 worldwide
Run by
Neurocrine Biosciences
See details and how to joinNCT07196501 · EU 2025-520541-72-00
Phase 3Enrolling by invitation
Phase III Long-term Extension Trial to Assess Safety and Efficacy of CYB003 in MDD (EXTEND)
Where
Maroochydore, Melbourne, Notting Hill
Age
18 years to 85 years
People
468 worldwide
Run by
Cybin IRL Limited
See details and how to joinNCT06605105 · EU 2024-516805-22-00
Phase 4Taking people
Positioning of Esketamine Treatment in the Real-world Management of Depression
Where
St Leonards
Age
18 years to 65 years
People
162
Run by
Royal North Shore Hospital
See details and how to joinNCT06103760
Phase 4Taking people
Comparative Effectiveness Study of Two Forms of Ketamine for Treatment-resistant Depression
Where
Camperdown, Melbourne, Parkville, Randwick, Southport, St Leonards, Warners Bay
Age
18 years and over
People
162
Run by
The George Institute
See details and how to joinNCT06278779
No phaseTaking people
Maintenance rTMS for Depression (Maitr-De)
Where
Canberra
Age
18 years to 80 years
People
75 worldwide
Run by
University of California, San Diego
See details and how to joinNCT06938841
Phase 3Taking people
REVEAL Study - Diagnostic Testing for PTSD Using the Senseye Diagnostic Tool
Where
Carlton
Age
18 years and over
People
1,900 worldwide
Run by
Senseye, Inc.
See details and how to joinNCT07280065
Phase 1/2Not yet taking people in Australia
Ketamine-Enhanced Therapy for Individuals With Alcohol Use Disorder and Depression: A Pilot Study (KET-DUAL)
Where
Sydney
Age
18 years to 70 years
People
20
Run by
South West Sydney Local Health District
See details and how to joinNCT07247370
No phaseNot yet taking people in Australia
Assessment of Whether Telehealth Family Psychoeducation for Major Depressive Disorder is Doable
Where
Bakewell, Palmerston
Age
18 years and over
People
26
Run by
University of Southern Queensland
See details and how to joinNCT07014241