Depression trials in Brazil

In Brazil 10 Also abroad 666

10 trials · From ClinicalTrials.gov, checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 3Taking people
A Study of Brenipatide in Adult Participants With Major Depressive Disorder
Where
Belo Horizonte, Curitiba, Marília, Maringá, Natal, Rio de Janeiro, São Bernardo do Campo, São Paulo, Valinhos
Age
18 years to 75 years
People
1,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07412756 · EU 2025-522308-25-00
Phase 3Taking people
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
Where
Brasília, Campinas, Criciúma, Natal, Passo Fundo, Porto Alegre, Rio de Janeiro, São Bernardo do Campo, São Paulo
Age
18 years to 74 years
People
752 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06559306 · EU 2023-509070-36-00
Phase 3Taking people
A Study to Evaluate the Efficacy and Safety of Esketamine for Reduction of Symptoms of Major Depressive Disorder
Where
Criciúma, Natal, Salvador, São Bernardo do Campo, São Paulo
Age
12 years to 17 years
People
258 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07227454 · EU 2024-518615-19-00
Phase 3Taking people
A Study of Seltorexant as Monotherapy in Adults and Elderly Participants With Major Depressive Disorder
Where
Salvador, São Bernardo do Campo, São Paulo
Age
18 years to 74 years
People
600 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT07573176
Phase 3Taking people
A Study of Brenipatide (LY3537031) in Adult Participants With Major Depressive Disorder
Where
Campinas, Curitiba, Joinville, Passo Fundo, Recife, São Bernardo do Campo, São José do Rio Preto, São Paulo, Vitória, Votuporanga
Age
18 years to 75 years
People
1,000 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07775300 · EU 2025-522310-24-00
Phase 2Taking people
Inhaled DMT for Major Depressive Disorder
Where
Fortaleza, Natal, Rio de Janeiro, Salvador, São Paulo
Age
18 years and over
People
140
Run by
Universidade Federal do Rio Grande do Norte
See details and how to joinNCT07562191
Phase 1/2Taking people
Cannabidiol Oil for Treatment-Resistant Major Depression
Where
Tubarão
Age
18 years to 69 years
People
120
Run by
Universidade do Sul de Santa Catarina
See details and how to joinNCT07696871
Phase 2Not yet taking people in Brazil
Triple-Blind Randomized Clinical Trial of Tocilizumab vs Placebo: Potential Use of an IL-6 Antagonist as an Adjuvant to Standard Treatment for Treatment-Resistant Major Depression in the Brazilian Public Health System (SUS)
Where
Porto Alegre
Age
18 years to 65 years
People
32
Run by
Hospital de Clinicas de Porto Alegre
See details and how to joinNCT07052058
Phase 1/2Taking people
Psilocybe Cubensis Mushrooms With or Without Fluoxetine for Refractory Depression
Where
Foz do Iguaçu
Age
25 years to 65 years
People
24
Run by
Federal University of Latin American Integration
See details and how to joinNCT06898606
No phaseTaking people
Psychoeducational Group for Depression
Where
São Paulo
Age
18 years to 59 years
People
338
Run by
Ricardo Alberto Moreno, M.D., Ph.D.
See details and how to joinNCT06467474