Depression trials in Bulgaria

In Bulgaria 13 Also abroad 666

13 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 11 November 2026. Ask the study team whether a trial fits you.

Phase 2Taking people
A Study to Evaluate the Efficacy and Safety of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 Study)
Where
Lovech, Plovdiv, Sofia
Age
18 years to 65 years
People
360 worldwide
Run by
Seaport Therapeutics
See details and how to joinNCT07065240 · EU 2025-521240-37-00
Phase 2Enrolling by invitation
An Open-Label Extension Study to Evaluate the Safety and Tolerability of SPT-300 (GlyphAllo) in Participants With Major Depressive Disorder, With or Without Anxious Distress (BUOY-1 OLE Study)
Where
Lovech, Plovdiv, Sofia
Age
18 years to 66 years
People
360 worldwide
Run by
Seaport Therapeutics
See details and how to joinNCT07161700 · EU 2025-522347-18-00
Phase 2Not yet taking people in Bulgaria
A Study of Brenipatide in Participants With Major Depressive Disorder
Where
Pleven, Plovdiv, Sofia, Varna, Vratsa
Age
18 years to 75 years
People
330 worldwide
Run by
Eli Lilly and Company
See details and how to joinNCT07928245 · EU 2026-527689-65-00
Phase 3Taking people
A research study to compare the antidepressant ability and safety of Samyr® tablets versus placebo tablets as an adjunct to additional antidepressant treatment in patients with major depressive disorder (MDD)
Where
Cherven Bryag, Plovdiv, Ruse, Sofia, Sofiya, Vratsa
Age
18 years and over
People
868 worldwide
Run by
Mylan Inc.
See details and how to join2024-513019-29-00 · EU 2024-513019-29-00
Phase 3Taking people
Study of Lumateperone as Adjunctive Therapy in the Treatment of Patients With Major Depressive Disorder
Where
Cherven Bryag, Kirdzhali, Pleven, Plovdiv, Sofia, Sofiya, Stara Zagora, Varna
Age
18 years to 65 years
People
470 worldwide
Run by
Intra-Cellular Therapies, Inc.
See details and how to joinNCT05850689 · EU 2023-503836-41-00
Phase 3Taking people
Phase 3 Study of Adjunctive Treatment With Seltorexant in Adult and Elderly Participants With Major Depressive Disorder and Insomnia Symptoms
Where
Burgas, Plovdiv, Sofia, Sofiya, Stara Zagora, Varna
Age
18 years to 74 years
People
752 worldwide
Run by
Janssen Research & Development, LLC
See details and how to joinNCT06559306 · EU 2023-509070-36-00
Phase 3Taking people
Long-Term Study to Assess the Safety and Tolerability of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Where
Kirdzhali, Plovdiv, Ruse, Sofia, Sofiya, Varna
Age
18 years and over
People
850 worldwide
Run by
Neurocrine Biosciences
See details and how to joinNCT06966401 · EU 2024-519423-24-00
Phase 3Taking people
A Study to Evaluate the Maintenance Effect of Osavampator as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Where
Sofia, Sofiya, Varna
Age
18 years and over
People
550 worldwide
Run by
Neurocrine Biosciences
See details and how to joinNCT07196501 · EU 2025-520541-72-00
Phase 2Taking people
A Study to Evaluate the Effectiveness of DT-101 in Patients With Depression
Where
Kazanlak, Plovdiv, Sofia, Vratsa
Age
18 years to 75 years
People
300 worldwide
Run by
Draig Therapeutics Ltd
See details and how to joinNCT07300969
Phase 3Taking people
Evaluation of Efficacy and Safety of Milsaperidone as Adjunctive Therapy in Patients With Major Depressive Disorder
Where
Kirdzhali, Pleven, Plovdiv, Sofia, Targovishte, Varna, Vratsa
Age
18 years to 65 years
People
500 worldwide
Run by
Vanda Pharmaceuticals
See details and how to joinNCT06830044 · EU 2024-520333-68-00
Phase 2Taking people
DT-101 in Adults with Major Depressive Disorder
Where
Cherven Bryag, Kazanlik, Plovdiv, Sofia, Sofiya, Vratsa
Age
18 years and over
People
175 worldwide
Run by
Draig Therapeutics Limited
See details and how to join2025-522784-15-00 · EU 2025-522784-15-00
Phase 3Taking people
NBI-1065845-MDD3025: Study to Assess the Efficacy and Safety of NBI-1065845 as an Adjunctive Treatment in Participants With Major Depressive Disorder (MDD)
Where
Kirdzhali, Plovdiv, Ruse, Sofiya, Varna
Age
18 years and over
People
200 worldwide
Run by
Neurocrine Biosciences
See details and how to joinNCT06911112 · EU 2024-519420-25-00
Phase 4Not yet taking people in Bulgaria
Evaluation of the efficacy of Trazodone in improving emotional blunting symptoms in Patients with Major Depressive Disorder
Where
Kazanlik, Plovdiv, Sofia
Age
18 years to 64 years
People
120 worldwide
Run by
Angelini Pharma Italia Aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A. Enunciabile Anche Angelini Pharma Italia S.p.A. Angelini Pharma S.p.A. A.C.R.A.F. S.p.A. Acraf S.p.A. Angelini S.p.A. aziende Chimiche Riunite Angelini Francesco A.C.R.A.F. S.p.A.
See details and how to join2025-523267-38-00 · EU 2025-523267-38-00