Depression trials in Germany

In Germany 37 Also abroad 664

37 trials · From ClinicalTrials.gov and EU CTIS (euclinicaltrials.eu), checked 10 November 2026. Ask the study team whether a trial fits you.

No phaseEnrolling by invitation
The Effect of Digital Markers in the Self-management of Depressive Symptoms
Where
Frankfurt
Age
18 years and over
People
660 worldwide
Run by
Mental Health Centre Copenhagen, Bispebjerg and Frederiksberg Hospital
See details and how to joinNCT06919133
No phaseTaking people
tVNS, Motivation, and Insulin Sensitivity
Where
Bonn
Age
18 years to 60 years
People
120
Run by
University of Bonn
See details and how to joinNCT07198100
Phase 1/2Taking people
Enoxolone in Major Depression - Biomarker-outcome Relationship
Where
Marburg
Age
18 years and over
People
80
Run by
Philipps University Marburg
See details and how to joinNCT05570110
No phaseTaking people
Precision Subclassification of Mental Health in Diabetes: Digital Twins for Precision Mental Health to Track Subgroups
Where
Bad Mergentheim, Würzburg
Age
18 years to 80 years
People
1,809
Run by
Forschungsinstitut der Diabetes Akademie Mergentheim
See details and how to joinNCT07212075
Phase 3Taking people
The Effect of a Six Week Intensified Pharmacological Treatment for Bipolar Depression Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.
Where
Bielefeld, Dortmund, Frankfurt am Main, Mainz, Muenster
Age
18 years and over
People
418 worldwide
Run by
Dr. Inge Winter
See details and how to joinNCT05973786 · EU 2023-506605-19-00
Phase 3Taking people
The Effect of a Six Week Intensified Pharmacological Treatment for Major Depressive Disorder Compared to Treatment as Usual in Subjects Who Had a First-time Treatment Failure on Their First-line Treatment.
Where
Bielefeld, Dortmund, Frankfurt am Main, Muenster
Age
18 years to 65 years
People
418 worldwide
Run by
Dr. Inge Winter
See details and how to joinNCT05973851 · EU 2023-506617-21-00
No phaseEnrolling by invitation
Virtual Reality-Augmented At-Home tDCS for Major Depression
Where
Munich
Age
18 years to 65 years
People
30
Run by
Technical University of Munich
See details and how to joinNCT07146269
No phaseEnrolling by invitation
Development and Evaluation of a Digital Aftercare Program for Adolescents (12-17 Years) With Depressive Symptoms After Hospital Discharge (Mind-WIN Pilot Study) (Mind-WIN Pilot)
Where
Hamburg, Lubin, Stadtroda
Age
12 years to 17 years
People
120
Run by
Universitätsklinikum Hamburg-Eppendorf
See details and how to joinNCT07007247
No phaseTaking people
The Effect of Mediterranean Diet and Mindfulness Eating on Depression Severity in People With Obesity and Major Depressive Disorder
Where
Stuttgart
Age
18 years and over
People
64
Run by
University Hospital Tuebingen
See details and how to joinNCT06621394
Phase 2Taking people
Pharmacologic Treatment Augmentation in Chronic Depression
Where
Berlin, Jena, Munich, Tuebingen
Age
18 years to 64 years
People
60
Run by
University Hospital Tuebingen
See details and how to joinNCT06410599 · EU 2024-512478-86-00
No phaseEnrolling by invitation
Non-invasive Vagus Nerve Stimulation as a Tool to Modulate Stomach-Brain Coupling in Depression
Where
Bonn
Age
18 years to 55 years
People
80
Run by
University of Bonn
See details and how to joinNCT06389175
No phaseNot yet taking people in Germany
Prediction and Validation of Unipolar Depression With Psychosocial-somatic Markers in a Naturalistic Cohort Recruited in an Outpatient Setting
Where
Munich
Age
18 years to 70 years
People
950
Run by
Julia Eder
See details and how to joinNCT05547711