Depression: open trials in United States

• NCT05570812

  Neuroactive Steroid to Treat Depressed Mood: A Trial for People With HIV

  Trial Treatment · Phase 2 · Massachusetts General Hospital

  Massachusetts General Hospital, Boston

  Registry updated 2025-09-12

• NCT04296604

  Transcranial Direct Current Stimulation (tDCS) Neuromodulation of Executive Function Across Neuropsychiatric Populations

  Trial Treatment · Massachusetts General Hospital

  Massachusetts General Hospital, Boston

  Registry updated 2025-09-10

• NCT06580041

  Precision Care for Major Depressive Disorder

  Trial Treatment · Phase 4 · University of California, San Francisco

  Nancy Friend Pritzker Psychiatry Building, University of California, San Francisco, San Francisco

  Registry updated 2025-09-05

• NCT06792175

  Mental Health, Intellectual and Neurodevelopmental Disorder Detection With Artificial Intelligence Models

  Research · Psyrin Inc.

  The Brookline Center, Brookline · Allwell Behavioral Health Services, Zanesville

  Registry updated 2025-09-03

• NCT03859297

  Mechanisms of Rumination Change in Adolescent Depression

  Trial Treatment · Ohio State University

  Nationwide Children's Hospital, Columbus · The Ohio State University, Columbus · University of Utah, Salt Lake City

  Registry updated 2025-08-11

• NCT07095205

  PET Imaging Using the Tracer [18F]VAT to Assess the Antidepressant Effect of Nicotine.

  Trial Treatment · Phase 4 · Stony Brook University

  Stony Brook University: Dept of Psychiatry, Stony Brook

  Registry updated 2025-07-31

• NCT07052357

  Intern Health Study 2025

  Trial Treatment · University of Michigan

  University of Michigan, Ann Arbor

  Registry updated 2025-07-04

• NCT06728774

  Cognitive Rehabilitation for Veterans With MDD-related Cognitive Functioning Deficits

  Trial Treatment · Portland VA Medical Center

  Portland VA Medical Center, Portland

  Registry updated 2025-06-06

• NCT06748950

  Ketogenic Metabolic Therapy in Schizophrenia, Bipolar Disorder, Major Depressive Disorder: Deep Omic Profiling

  Trial Treatment · Stanford University

  Stanford University, Palo Alto

  Registry updated 2025-05-16

• NCT06823024

  Assess the Utility of a Speech-based Machine Learning Algorithm to Predict Treatment Response to Psychiatric Interventions

  Research · Psyrin Inc.

  Fermata Health, New York · Acacia Clinics, Sunnyvale

  Registry updated 2025-03-18

• NCT06223880

  A Study to Evaluate the Efficacy of AXS-05 Compared to Bupropion in Preventing the Relapse of Depressive Symptoms

  Trial Treatment · Phase 4 · Axsome Therapeutics, Inc.

  Atlanta · Bellflower · Boston · Brandon · Brooklyn · Cherry Hill · Chicago · Cincinnati · Dallas · Doral · Edmond · Everett · Friendswood · Hialeah · Hickory · Jacksonville · Lafayette · Las Vegas · Memphis · Miami · Mount Kisco · New Orleans · New York · Oceanside · Oklahoma City · Orlando · Overland Park · Portland · Redlands · Riverside · Saint Charles · San Antonio · San Diego · Staten Island · Toms River · Upland · Wichita Falls

  Registry updated 2025-01-23

• NCT06695767

  Neurobehavioral Therapy For Epilepsy And Major Depressive Disorder

  Trial Treatment · The University of Texas Health Science Center, Houston

  Michael E. DeBakey VA Medical Center, Houston · The University of Texas Health Science Center at Houston, Houston

  Registry updated 2025-01-09

• NCT06070766

  RIVER At Home Ketamine Protocols

  Research · RIVER Foundation

  RIVER Foundation, Bigfork · RIVER Telehealth, Helena

  Registry updated 2024-11-26

• NCT06005194

  InMotion - Telehealth Delivered Exercise Promotion to Treat Major Depression After TBI

  Trial Treatment · University of Washington

  University of Washington Medical Center, Seattle

  Registry updated 2024-09-19

• NCT06470035

  Electrical Vestibular Nerve Stimulation (VeNS) as a Treatment for Major Depressive Disorder (MDD)

  Trial Treatment · Neurovalens Ltd.

  VA San Diego Healthcare System, San Diego

  Registry updated 2024-08-09

• NCT06512324

  Operation of Brain Stimulation Equipment Under Remote Viewing Effectiveness Registry

  Research · Biomedical Discoveries and Neuroscientific Foundations LLC

  Kind Health Group, Encinitas · Salience Research Institute, Plano

  Registry updated 2024-07-22

• NCT06228391

  Ketamine Treatment for PTSD and MDD in TBI

  Trial Treatment · Phase 2 · Minneapolis Veterans Affairs Medical Center

  Minneapolis VA Medical Center, Minneapolis

  Registry updated 2024-01-29

• NCT05011864

  Integrated Tele-Behavioral Activation and Fall Prevention for Low-income Homebound Seniors With Depression

  Trial Treatment · University of Texas at Austin

  University of Texas at Austin, Austin

  Registry updated 2024-01-09

• NCT06101914

  Studying Patterns in Patient Engagement Among Treatment Resistant Depression Patients

  Research · Power Life Sciences Inc.

  Power Life Sciences, San Francisco

  Registry updated 2023-10-26

• NCT05366270

  Peripheral Neuroimmune Mechanisms of Hyperthermia

  Trial Treatment · Massachusetts General Hospital

  Massachusetts General Hospital Depression Clinical & Research Program, Boston

  Registry updated 2023-03-10

All Depression trials and the map

This page is not medical advice. Talk to your doctor before contacting a trial.

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